BILL ANALYSIS                                                                                                                                                                                                    



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          Date of Hearing:   July 7, 2009

                            ASSEMBLY COMMITTEE ON HEALTH
                                  Dave Jones, Chair
                     SB 161 (Wright) - As Amended:  May 21, 2009

           SENATE VOTE  :   36-0
           
          SUBJECT  :   Health care coverage: cancer treatment.

           SUMMARY  :   Requires a health care service plan (health plan)  
          contract or health insurance policy that provides coverage for  
          anticancer treatment to provide coverage for a prescribed,  
          orally administered anticancer medication on a basis no less  
          favorable than intravenously administered or injected anticancer  
          medications.  Specifically,  this bill  :

          1)Requires health plan contracts and health insurance policies  
            issued, amended, or renewed on or after January 1, 2010, that  
            provide coverage for anticancer treatment to provide coverage  
            for a prescribed, orally administered anticancer medication  
            used to kill or slow the growth of cancerous cells on a basis  
            "no less favorable" than intravenously administered or  
            injected anticancer medications covered under the contract.

          2)Requires health plan contracts and health insurance policies,  
            in order to comply with 1) above to review the percentage cost  
            share for oral anticancer medications and intravenous (IV) or  
            injected anticancer medications and to apply the lower of the  
            two as the cost-sharing provision for oral cancer medications.

          3)Prohibits health plans and health insurance policies from  
            increasing enrollee cost sharing for anticancer medications.

          4)Defines "cost share" to mean copayment, coinsurance, or  
            deductible provisions applicable to coverage for oral, IV or  
            injected anticancer medications.

          5)Exempts from this bill health plan contracts or health  
            insurance policies purchased by the Board of Administration of  
            the Public Employees' Retirement System (CalPERS) pursuant to  
            the Public Employees' Medical and Hospital Care Act.

           EXISTING LAW  :









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          1)Provides for the regulation of health plans by the Department  
            of Managed Health Care (DMHC) and regulation of disability  
            insurers who sell health insurance by the California  
            Department of Insurance (CDI).

          2)Requires health plan contracts and health insurance policies  
            to provide coverage for all generally medically accepted  
            cancer screening tests and requires those plans and policies  
            to also provide coverage for the treatment of breast cancer.

          3)Imposes various requirements on contracts and policies that  
            cover prescription drug benefits, such as a requirement to  
            cover "off-label" uses, as specified, and a requirement to  
            cover previously prescribed drugs, as specified.
          4)Authorizes DMHC to regulate the provision of medically  
            necessary prescription drug benefits by a health plan to the  
            extent that the plan provides coverage for those benefits.   
            Existing regulation requires health plans providing outpatient  
            prescription drugs to provide all medically necessary  
            prescription drugs, except as specified in that regulation.

           FISCAL EFFECT  :   DMHC and CDI's regulatory activity is supported  
          by fee revenues in special funds, the Managed Care Fund and the  
          Insurance Fund, respectively.  According to the Senate  
          Appropriations Committee analysis, depending on the complexity  
          of any necessary regulations, it could cost DMHC from the  
          Managed Care Fund $5,000-$10,000 for fiscal years (FYs) 2009-10  
          and 2010-11 and $50,000-$150,000 for FY 2011-12, to promulgate  
          regulations to implement this bill.

           COMMENTS  :    

           1)PURPOSE OF THIS BILL  .  According to the author, the emergence  
            of safe, clinically effective, orally administered anticancer  
            medication has significantly increased the treatment options  
            for cancer patients; however, many barriers currently impede  
            the adoption of orally administered treatment as the main form  
            of cancer therapy.  The author maintains that one of the most  
            significant barriers is greater patient out-of-pocket costs  
            for oral therapies covered under the pharmacy benefit than IV  
            therapies covered under the medical benefit.  The author  
            further maintains that, where intravenously administered  
            anticancer medications are typically covered under a plan's  
            medical benefit, most patients are only responsible for an  
            office co-payment for each episode of care and are not  








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            required to pay a separate fee for the IV drug.  The author  
            argues that, in contrast, orally administered anticancer  
            medications are typically covered under a plan's pharmacy  
            benefit, where many of these agents are placed on a 4th or  
            specialty tier of a prescription plan's formulary.  The author  
            points out that, according to the Kaiser Family Foundation,  
            the average coinsurance rate for 4th tier drugs is 28%, which,  
            for a $3,000 per month oral anticancer medication, could  
            expose a patient to $900 in out-of-pocket spending.  The  
            author believes that this disparity restricts patient access  
            to life-saving oral anticancer therapies.  

          The author additionally points out that, in 2007, the Oregon  
            State Senate passed similar legislation (S.B. 8 (Courtney),  
            Chapter 566, 2007 Laws), and that, upon enactment of S.B. 8 in  
            January 2008, the top state plans eliminated their high  
            coinsurance rates.  Most Oregon plans established separate  
            oral anticancer therapy coverage under their pharmacy benefit,  
            and patients with no pharmacy benefits gained access to oral  
            anticancer agents through their medical benefit.  The author  
            further notes that, the Indiana Legislature passed a similar  
            bill in April 2008, and this year several other states have  
            introduced similar oral anticancer therapy parity legislation  
            including: Texas, Washington, Hawaii, Indiana, and Oklahoma.    


           2)CALIFORNIA HEALTH BENEFITS REVIEW PROGRAM  .  AB 1996 (Thomson),  
            Chapter 795, Statutes of 2002, requests the University of  
            California to assess legislation proposing a mandated benefit  
            or service, and prepare a written analysis with relevant data  
            on the medical, economic, and public health impacts of  
            proposed health plan and health insurance benefit mandate  
            legislation.  The California Health Benefits Review Program  
            (CHBRP) was created in response to AB 1996 and extended for  
            four additional years in SB 1704 (Kuehl), Chapter 684,  
            Statutes of 2006.  In its analysis of AB 513, CHBRP reports:
           
             a)   Overview of Oral Anti-Cancer Medications  .  CHBRP reports  
               that, nearly one in two Californians born today will  
               develop cancer at some point in their lifetime.  There are  
               an estimated 140,000 cases of cancer diagnosed each year,  
               while approximately 1.2 million Californians alive today  
               have a history with the disease.  According to CHBRP,  
               breast cancer is the most prevalent cancer in California.   
               Sixty-five percent of the prescriptions and 33% of the  








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               total cost for oral anticancer medications are for drugs  
               used to treat breast cancer.  After breast cancer, the next  
               three most common cancers in California are colorectal,  
               prostate, and lung cancer.  Non-Hispanic blacks in  
               California have higher rates of diagnoses of these three  
               cancers compared to all other racial and ethnic groups.   
               These three cancers are all treated using oral anticancer  
               medications; therefore, to the extent that this bill  
               reduces out-of-pocket costs for oral anticancer  
               medications, non-Hispanic black cancer patients could face  
               a reduced financial burden.

             According to CHBRP, oral anticancer medications are used  
               alone or in combination with other oral, IV, or injected  
               anticancer medications, depending on the cancer they are  
               being used to treat.  For many oral anticancer medications,  
               there are no IV or injected substitutes (and vice versa);  
               there are, however, some important exceptions.  Generally,  
               the manner in which anticancer medications are administered  
               depends upon the specific medicine.

             CHBRP states, the most frequently prescribed oral anticancer  
               medications in California in 2006 were three hormone drugs  
               used to treat breast, ovarian, endometrial, and uterine  
               cancers.  The most expensive oral anticancer medications  
               prescribed to Californians are Revlimid (for multiple  
               myeloma and myelodysplastic syndromes), Sutent (for  
               gastrointestinal stromal tumors and for kidney, renal cell,  
               and thyroid cancers), and Nexavar (for hepatocellular,  
               kidney, renal cell, and thyroid cancers). 

             CHBRP maintains that oral anticancer medications are being  
               prescribed more frequently for cancer treatment.  Four of  
               the five most prevalent cancers in California, including  
               breast, colorectal, prostate, and lung cancers, can be  
               treated using oral anticancer medications.  To date the  
               federal Food and Drug Administration has approved 38 oral  
               anticancer medications used to treat 52 different types of  
               cancer.  According to the National Comprehensive Cancer  
               Network, experts estimate that 400 anticancer medications  
               are currently under development and an estimated 25% of  
               anticancer agents currently in development are oral  
               anticancer treatments.  

             When compared to IV and injectable anticancer medications,  








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               oral anticancer medications have both advantages and  
               disadvantages.  According to CHBRP, advantages include that  
               oral anticancer medications may allow administration of the  
               medication on a daily basis; may be more convenient for  
               patients; and, may reduce the risk of infection or other  
               infiltration complications.  Disadvantages include less  
               certainty in patient adherence to treatment regimens and a  
               reduction in interaction between patients and their health  
               care providers to manage complications of treatment. 

              b)   Anticancer Medication Coverage  .  CHBRP reports that  
               coverage for anticancer medications can differ in any of a  
               number of ways, depending on provisions of a person's  
               contract or policy with a health plan or insurer.  At a  
               very broad level, anticancer medications may be covered as  
               pharmacy plan benefits or as medical plan benefits, and  
               most plans and insurers depend on the dispensing site to  
               determine which will be the form of coverage.  IV  
               anticancer medication, which is usually provided in a  
               hospital or a physician's office, is generally covered as a  
               medical benefit.  Oral anticancer medications (usually  
               pills) dispensed by a pharmacy are usually covered as a  
               pharmacy benefit.  Some injected anticancer medications are  
               considered "self-injectable," and so are regularly  
               delivered through a pharmacy and covered as a pharmacy  
               benefit.  In part, these variations are due to the fact  
               that pharmacy benefits are relatively new for health plans  
               and policies, having been added in the 1970s and 1980s,  
               long after hospitalization and physician visits had become  
               covered medical benefits. 

             CHBRP indicates for both medical and pharmacy benefits,  
               payers have devised strategies to promote appropriate  
               utilization and control of costs.  A short list of these  
               strategies includes: creation of formularies; maximization  
               of manufacturer rebates; quantity restrictions; use of  
               prior authorization; development of clinical guidelines;  
               and, implementation of patient cost sharing, such as  
               deductibles, coinsurance, and copayments.  Cost sharing for  
               medications is frequently complicated by tiered pricing.  A  
               plan or insurer may assign drugs to tiers (generic drugs in  
               the lowest and very expensive drugs in the highest) and  
               apply varying copayments and coinsurance rates to different  
               tiers.  As with cost sharing in general, the impact of  
               tiers (if any) depends on the specifics of a person's  








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               contract or policy. 

             According to CHBRP, the variety of cost sharing provisions  
               currently used in California makes it difficult to  
               generalize about the ways in which a cancer patient may be  
               required to pay out-of-pocket for any anticancer  
               medication.  Fixed copayments are a common form of cost  
               sharing for medications delivered through a pharmacy.   
               However, some plans and polices specify coinsurance for one  
               or more medications.  The terms of coverage may or may not  
               include a deductible.  The coverage of medications  
               delivered as medical benefits is equally variable.
               
              c)   Utilization, Cost and Coverage Impacts  .  Based on the  
               results of CHBRP's survey of the six largest plans and  
               insurers, 100% of enrollees are estimated to have at least  
               some coverage for inpatient anticancer medications and  
               outpatient IV and injected anticancer medications, while  
               97.8% of enrollees are estimated to have at least some  
               coverage for outpatient oral anticancer medications.   
               Approximately 472,000 enrollees (2.2%) have no coverage for  
               outpatient oral anticancer medication.  This group includes  
               persons with coverage from small group or individual market  
               policies regulated by CDI. 

             CHBRP states that only 66% of individual market policies  
               regulated by CDI cover oral anticancer medications, in  
               comparison to 88% of small group policies under CDI.  
               (However, CDI indicates that oral anticancer medication for  
               breast cancer is covered under all CDI products, which  
               CHBRP discounted for this analysis, based on survey  
               results).  One hundred percent of large group policies  
               under CDI covered oral anticancer medications, as did all  
               other market segments.

             CHBRP estimates that 0.5% of people with coverage subject to  
               the mandate will use oral anticancer medications during the  
               year following implementation.  Of the people using  
               anticancer medications, CHBRP estimates that 69.5% use oral  
               only, 20.2% use injected or IV only, and 10.3% use a  
               combination of oral and injected/IV anticancer medications.  


             According to CHBRP, the greatest impact on premiums will be  
               in the small group and individual markets regulated by CDI.  








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                While it is possible that this bill will have the  
               unintended consequence of causing small group employers or  
               individuals to drop health care coverage altogether as a  
               result of an increase in premiums, CHBRP projects no  
               measurable impact on the number of persons who are  
               uninsured because the estimated premium increase is 0.025%  
               - which is less than the 1% threshold at which CHBRP would  
               estimate a change in the number of persons covered by  
               insurance.

             CHBRP states that this bill would affect the coverage of more  
               than 21.3 million persons enrolled in group or individual  
               insurance plans or policies in California with anticancer  
               therapy coverage.  CHBRP maintains that it is   expected to  
               increase the premiums paid by both employers and employees  
               (by almost $19.7 million), and would cause a decrease in  
               the out-of-pocket costs paid by members using oral  
               anticancer medications incurred through the cost sharing  
               provisions of a policy or contract (by almost $14.7  
               million).  Total net annual expenditures are estimated to  
               increase by $5 million annually, or 0.0059%, mainly due to  
               administrative costs.

             Of the expected premium increase of about $19,674,000, total  
               premiums for private employers are estimated to increase by  
               $7,287,000, or 0.0144%.  

             Medi-Cal Managed Care plans and the Healthy Families program  
               would not be expected to face any expenditure or premium  
               increases because they currently provide oral anticancer  
               medication benefits in accordance with the coverage  
               mandated by this bill.  
             As recently amended, this bill excludes the CalPERS from the  
               provisions of this bill, therefore reducing costs to the  
               state.

             CHBRP reports that approximately 1.6% of the enrollees who  
               use oral anticancer medications have out-of-pocket costs  
               for such medications over $1,000 per year.  Post-mandate  
               amounts shifted from patient to plan/insurer would range  
               from $0 to $7,800 per user per year.  The wide variation is  
               related to the price of particular oral anticancer  
               medications and the cost sharing provisions of any one  
               person's contract or policy. 









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             According to CHBRP, utilization of oral anticancer  
               medications is not expected to increase as a result of this  
               bill, as 97.8% of enrollees with coverage subject to the  
               mandate already have some coverage for oral anticancer  
               medications, public and private assistance programs exist,  
               price elasticity of demand for anticancer medications is  
               low (as patients will do whatever they can to comply with  
               prescribed treatments, given the life-threatening nature of  
               the illness), and oncologists prescribing behaviors are  
               unlikely to change materially.  Therefore, according to  
               CHBRP, the only potential public health impact as a result  
               of this bill is a reduction in out-of-pocket costs for oral  
               anticancer medications. 

             CHBRP states longer-term impacts on health care costs as a  
               result of the mandate are unknown but are likely to  
               increase over time.  It is estimated that a quarter of  
               chemotherapy treatments in the pipeline are planned as oral  
               medications.  According to a recent pharmaceutical report  
               on cancer medication development, almost 650 new  
               medications and new indications for existing cancer  
               medications are in clinical development.  Several other  
               factors may be influential, such as an increase in the  
               number of patients receiving long-term treatment with more  
               targeted oral anticancer medications, continued growth in  
               the use of combination treatment for various types of  
               cancers, and expanding indications or off-label use of  
               existing drugs for the treatment of various cancers.

              d)   Administrative Costs  .  According to CHBRP, health plans  
               and health insurers policies include a component for  
               administration and profit in their premiums.  In estimating  
               the impact of this mandate on premiums, CHBRP states that,  
               actuarial analysis assumes that plans and insurers will  
               apply their existing administration and profit loads to the  
               increase in health care costs produced by this bill.   
               Therefore, CHBRP indicates, although there may be  
               administrative costs associated with the mandate,  
               administrative costs as a portion of premiums would not  
               change.  In addition, this bill requires that plans and  
               insurers notify members and applicants of their oral  
               chemotherapy coverage changes.  Health plans and insurers  
               may also need to increase staff specializing in utilization  
               management.  
             








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          1)SUPPORT  .  Carrie's Touch and The American Caner Society,  
            sponsors of this bill, state that this is an important issue  
            to address as more and more cancer therapies move toward being  
            provided through oral anticancer medications.  Both  
            organizations maintain that many of the oral anticancer  
            treatments do not have IV counterparts, making the need to  
            ensure access to them critical.  Carrie's Touch, an  
            organization dedicated to addressing the fight against breast  
            cancer in the African American community, indicates that oral  
            anticancer treatments improve patients' quality of life,  
            provide a more convenient and less invasive method of therapy  
            and could potentially reduce resource utilization and health  
            care system costs, while improving patient satisfaction.  

          The California Medical Association and the Association of  
            Northern California Oncologists (ANCO) also support this bill.  
             ANCO states that it is the consensus opinion of the ANCO  
            Board of Directors based on their experience and expertise in  
            treating people with cancer, that prohibitive higher  
            out-of-pocket costs for people with cancer needing oral  
            anticancer medications can result in delayed cancer treatment  
            or in their receiving IV anticancer treatments that are less  
            convenient for the patient and more costly to the healthcare  
            system (with their concomitant administrative and support drug  
            costs) in total than the originally prescribed oral anticancer  
            medication.  

          2)OPPOSITION  .  Anthem Blue Cross (Anthem), the Association of  
            California Life and Health Insurance Companies, and Health Net  
            are opposed to this bill.  Health insurers state that this  
            bill sets a dangerous precedent by requiring a more favorable  
            coverage of a specific type of medication.  Anthem states that  
            this bill would require health plans to cover all oral  
            anticancer drugs and completely disregards the current process  
            to place drugs onto a formulary.  According to Anthem, as a  
            result, pharmaceutical companies would have no incentive to  
            negotiate in good faith knowing that plans would be mandated  
            by law to have these specific drugs on their formulary.   
            Health Net also states that this bill inappropriately limits a  
            health plan's and insurer's flexibility to design their drug  
                formularies to determine the relative efficacy of covered  
            drugs.  

          The California Department of Managed Health Care, The California  
            Association of Health Plans (CAHP) and the California Chamber  








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            of Commerce are also opposed to the bill and state that they  
            are concerned that this bill could negatively impact  
            California's already struggling health care market and as a  
            result, some subscribers, particularly in the price-sensitive  
            individual and small group markets, could be forced to drop  
            health coverage altogether.  CAHP also states that there have  
            been a number of benefit mandates that have worked there way  
            through the Legislature in recent years and new mandates  
            increase the cost of health care and hinder a plan's ability  
            to offer a wider range of affordable products.  According to  
            CAHP, this results in higher premiums for individuals and  
            employers.  

          3)POLICY ISSUES  .  

              a)   From a policy perspective, the recent amendments to  
               exclude CalPERS from this bill's provisions appear to be  
               inconsistent with this bill's intent to make oral cancer  
               medications available to all persons with health coverage.   
               The author may wish to address the rationale for exempting  
               CalPERS from this bill.  

              b)   It is unclear what the meaning and impact would be of  
               the provision in this bill that prohibits health plans and  
               health insurance policies from increasing enrollee cost  
               sharing for anti-cancer medications.  Does the author  
               intend to prohibit increases in a contract or policy's  
               existing cost sharing elements?  Increases above those in  
               effect at the time of the enactment of this bill?   
               Increases on a year-to-year basis?  The author may wish to  
               clarify what is meant by this provision.  
           
           REGISTERED SUPPORT / OPPOSITION  :

           Support 
           
          American Cancer Society (cosponsor)
          Carrie's Touch (cosponsor)
          Association of Northern California Oncologists
          B and S Electric
          BayBio
          California Breast Cancer Organizations
          California Medical Association
          California State Conference of the National Association for the  
          Advancement of Colored People








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          De Luz Enterprises
          McKay Photography (prior version)
          National Patient Advocate Foundation (prior version)
          Northern California Cancer Center (prior version)
          Public Health Institute (prior version)
          Sacramento Breast Cancer Resource Center
          St. Andrews African Methodist Episcopal Church
            Saint James African Methodist Episcopal Church (prior version)
          Susan G. Komen for the Cure, California Affiliate Collaborative
          Wright Chapel African Methodist Episcopal Church
          Numerous individuals
           
          Opposition 
           
          Anthem Blue Cross
          Association of California Life & Health Insurance Companies
          Blue Shield of California
          California Association of Health Plans
          California Chamber of Commerce
          Department of Managed Health Care
          Health Net

           Analysis Prepared by  :    Tanya Robinson-Taylor / HEALTH / (916)  
          319-2097