BILL ANALYSIS                                                                                                                                                                                                    �



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        ASSEMBLY THIRD READING
        AB 714 (Wieckowski)
        As Amended May 24, 2013
        2/3 vote 

         HEALTH              16-2        APPROPRIATIONS      14-0         
         
         ----------------------------------------------------------------- 
        |Ayes:|Pan, Logue, Ammiano,      |Ayes:|Gatto, Harkey, Bocanegra, |
        |     |Atkins, Bonilla, Bonta,   |     |Bradford, Ian Calderon,   |
        |     |Chesbro, Gomez, Roger     |     |Campos, Eggman, Gomez,    |
        |     |Hern�ndez, Bocanegra,     |     |Hall, Ammiano, Linder,    |
        |     |Mitchell, Nazarian,       |     |Pan, Quirk, Weber         |
        |     |Nestande,                 |     |                          |
        |     |V. Manuel P�rez, Wagner,  |     |                          |
        |     |Wieckowski                |     |                          |
        |     |                          |     |                          |
        |-----+--------------------------+-----+--------------------------|
        |Nays:|Mansoor, Wilk             |     |                          |
        |     |                          |     |                          |
         ----------------------------------------------------------------- 
         SUMMARY  :  Appropriates $1 million from the General Fund (GF) to the  
        spinal cord injury (SCI) research fund authorized by the Roman Reed  
        Spinal Cord Injury Research Act of 1999 (Roman Reed Act).

         EXISTING LAW  establishes the Roman Reed Act and authorizes the  
        University of California (UC) to establish a SCI research fund to  
        accept public and private funds for the purpose of injury research  
        programs and grants.

         FISCAL EFFECT  :  According to the Assembly Appropriations Committee,  
        $1 million General Fund (GF) appropriation. 

         COMMENTS  :  According to the author, California is home to  
        approximately 650,000 people living with paralysis, and this number  
        is increasing steadily.  The author states nationally, someone  
        suffers a traumatic SCI every 41 minutes, adding anywhere from  
        12,000 to 20,000 new SCI patients annually.  According to a report  
        prepared for AB 1657 (Wieckowski), a similar bill from 2012, a  
        recent study commissioned by the Christopher and Dana Reeve  
        Foundation and the Centers for Disease Control and Prevention  
        reveals that approximately 5.6 million Americans are afflicted by  
        some form of paralysis, and almost 1.3 million individuals are  
        living with a catastrophic SCI.  The report states this is five  








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        times higher than earlier estimates of the prevalence of SCI in the  
        United States.  The author maintains that the disability, loss of  
        earning power, and loss of personal freedom resulting from SCI is  
        devastating for the injured individual and creates a huge financial  
        burden for the state.  The author asserts that associated health  
        care costs and lost income potential associated with spinal injuries  
        cost the State of California upwards of $1 billion per year.  The  
        author claims that promising research-driven therapies currently  
        underway could greatly improve the quality of life and functionality  
        of individuals with spinal cord injuries and offset a significant  
        portion of these state costs.  The author indicates that the funds  
        have resulted in remarkable research projects and at least 175  
        peer-reviewed publications and that discoveries financed by the fund  
        are in the pipeline toward clinical translation. 

        The author indicates that state funding for the Roman Reed Fund has  
        been eliminated, jeopardizing the research that this program  
        undertakes in spinal cord injuries and paralysis.  The author states  
        that by investing new funds in this research, California can ensure  
        the continued success of this impressive program and remain a world  
        leader in neural sciences.  This bill, the author maintains, will  
        provide the critical funding needed to make this program viable.  In  
        conclusion, the author points out that in vetoing AB 1657 in 2012  
        the Governor indicated that this type of valuable research should be  
        supported through general fund activities, rather than penalty  
        assessments on vehicle offenses and this bill addresses that veto  
        message. 

        AB 750 (Dutra), Chapter 777, Statutes of 2000, established the Roman  
        Reed Act to support scientific research related to spinal cord  
        injuries for five-years and was renewed for an additional five years  
        through AB 1794 (Dutra), Chapter 414, Statutes of 2004.  Over its  
        10-year history, the fund provided approximately $1.5 million per  
        year for SCI research in the State of California.  The Roman Reed  
        Act funds were allocated to the University of California (UC), and  
        administered by the Reeve-Irvine Research Center at UC Irvine.   
        According to the author, between 2000 and 2009, over 300 scientists,  
        technical staff, and students have participated in 129 Roman Reed  
        Research projects and that the $15.1 million in state contributions  
        to the Roman Reed Fund leveraged $84 million in non-state funds,  
        such as from the National Institutes of Health.  

        The Roman Reed Program has three components:  1) research grants to  
        promote innovative, high-impact research projects focusing on SCI or  








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        nerve cell regeneration.  Principal Investigators must be from  
        institutions within the State of California; 2) the Roman Reed Core  
        Laboratory which provides a means for investigators who are new to  
        the field of SCI research to launch novel research projects and  
        obtain training in SCI research techniques.  The main purpose of the  
        Core Laboratory is to support experiments by scientists with novel  
        ideas, but who are not yet directly engaged in SCI research in their  
        own labs; and, 3) an annual meeting fostering collaboration and  
        communication throughout California, both for scientists and the lay  
        public.  According to Dr. Oswald Steward, the Roman Reed Project  
        Director, there have been no grants funded by the Roman Reed Spinal  
        Cord Injury Research Act since 2010 (in other words, no funding from  
        the Legislature).  UC provided funding to continue the grants  
        program in a modified form for one additional year and it continues  
        to be called the "Roman Reed Program" for continuity.  These funds  
        were distributed in 2012.  A panel of experts from the SCI field  
        assembled to provide outside peer review of Roman Reed Grant  
        applications.  Submitted grants were evaluated for scientific merit  
        and the top 10 were funded.  A total of $749,311 in grants was  
        awarded.  

        Baybio, the California Healthcare Institute, and others write in  
        support that California is a leader in neurological and SCI  
        research.  Baybio further states in support that if we are to  
        maintain our prominence in this field of research, additional  
        funding for SCI research to replace GF contributions must be found  
        or we risk losing the matching funds and other grants that we  
        successfully attracted in the recent past.  According to supporters,  
        many discoveries supported by the fund are in the pipeline toward  
        clinical translation including:  1) the world's first clinical trial  
        for stem cells for SCI; 2) a treatment initially developed for SCI  
        in clinical trials for inflammatory bowel disease; and, 3) new  
        surgical techniques developed to treat people with nerve injuries.  

        The California Catholic Conference writes in opposition that  
        although recent amendments have shifted the funding from traffic  
        fines to the GF, this bill continues the unfortunate policy of  
        spending money on speculative research.  This opposition points out  
        that at a time in which we have cut funding for our state's safety  
        net-upon which our poor and vulnerable Californians rely-it is  
        highly inappropriate to divert money to University researchers.  


         Analysis Prepared by  :    Marjorie Swartz / HEALTH / (916) 319-2097 








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