BILL ANALYSIS                                                                                                                                                                                                    �



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          CONCURRENCE IN SENATE AMENDMENTS
          AB 714 (Wieckowski)
          As Amended June 24, 2013
          2/3 vote 
           
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          |ASSEMBLY:  |68-3 |(May 29, 2013)  |SENATE: |39-0 |(September 9,  |
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           Original Committee Reference:   HEALTH  

           SUMMARY  :  Appropriates $1 million from the General Fund (GF) to  
          the spinal cord injury (SCI) research fund authorized by the  
          Roman Reed Spinal Cord Injury Research Act of 1999 (Roman Reed  
          Act).

           The Senate amendments  are technical and nonsubstantive. 

           EXISTING LAW  establishes the Roman Reed Act and authorizes the  
          University of California (UC) to establish a SCI research fund  
          to accept public and private funds for the purpose of injury  
          research programs and grants.

           FISCAL EFFECT  :  According to the Senate Appropriations  
          Committee, one-time $1 million General Fund appropriation.

           COMMENTS  :  According to the author, California is home to  
          approximately 650,000 people living with paralysis, and this  
          number is increasing steadily.  The author states nationally,  
          someone suffers a traumatic SCI every 41 minutes, adding  
          anywhere from 12,000 to 20,000 new SCI patients annually.   
          According to a report prepared for AB 1657 (Wieckowski), a  
          similar bill from 2012, a study commissioned by the Christopher  
          and Dana Reeve Foundation and the federal Centers for Disease  
          Control and Prevention reveals that approximately 5.6 million  
          Americans are afflicted by some form of paralysis, and almost  
          1.3 million individuals are living with a catastrophic SCI.  The  
          report states this is five times higher than earlier estimates  
          of the prevalence of SCI in the United States.  The author  
          maintains that the disability, loss of earning power, and loss  
          of personal freedom resulting from SCI is devastating for the  
          injured individual and creates a huge financial burden for the  
          state.  The author asserts that associated health care costs and  
          lost income potential associated with spinal injuries cost the  








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          state upwards of $1 billion per year.  The author claims that  
          promising research-driven therapies currently underway could  
          greatly improve the quality of life and functionality of  
          individuals with spinal cord injuries and offset a significant  
          portion of these state costs.  The author indicates that the  
          funds have resulted in remarkable research projects and at least  
          175 peer-reviewed publications and that discoveries financed by  
          the fund are in the pipeline toward clinical translation. 

          The author indicates that state funding for the Roman Reed Fund  
          has been eliminated, jeopardizing the research that this program  
          undertakes in spinal cord injuries and paralysis.  The author  
          states that by investing new funds in this research, California  
          can ensure the continued success of this impressive program and  
          remain a world leader in neural sciences.  This bill, the author  
          maintains, will provide the critical funding needed to make this  
          program viable.  The author points out that in vetoing AB 1657  
          in 2012 the Governor indicated that this type of valuable  
          research should be supported through General Fund activities,  
          rather than penalty assessments on vehicle offenses and this  
          bill addresses that veto message. 

          AB 750 (Dutra), Chapter 777, Statutes of 2000, established the  
          Roman Reed Act to support scientific research related to spinal  
          cord injuries for five-years and was renewed for an additional  
          five years through AB 1794 (Dutra), Chapter 414, Statutes of  
          2004.  Over its 10-year history, the Roman Reed Fund provided  
          approximately $1.5 million per year for SCI research in the  
          State of California.  The Roman Reed Act funds were allocated to  
          University of California (UC), and administered by the  
          Reeve-Irvine Research Center at UC Irvine.  According to the  
          author, between 2000 and 2009, over 300 scientists, technical  
          staff, and students have participated in 129 Roman Reed Research  
          projects and that the $15.1 million in state contributions to  
          the Roman Reed Fund leveraged $84 million in non-state funds,  
          such as from the National Institutes of Health.

          The Roman Reed Program has three components:  1) research grants  
          to promote innovative, high-impact research projects focusing on  
          SCI or nerve cell regeneration.  Principal Investigators must be  
          from institutions within the State of California; 2) the Roman  
          Reed Core Laboratory which provides a means for investigators  
          who are new to the field of SCI research to launch novel  
          research projects and obtain training in SCI research  
          techniques.  The main purpose of the Core Laboratory is to  








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          support experiments by scientists with novel ideas, but who are  
          not yet directly engaged in SCI research in their own labs; and,  
          3) an annual meeting fostering collaboration and communication  
          throughout California, both for scientists and the lay public.   
          According to Dr. Oswald Steward, the Roman Reed Project  
          Director, there have been no grants funded by the Roman Reed  
          Spinal Cord Injury Research Act since 2010 (in other words, no  
          funding from the Legislature).  UC provided funding to continue  
          the grants program in a modified form for one additional year  
          and it continues to be called the "Roman Reed Program" for  
          continuity.  These funds were distributed in 2012.  A panel of  
          experts from the SCI field assembled to provide outside peer  
          review of Roman Reed Grant applications.  Submitted grants were  
          evaluated for scientific merit and the top 10 were funded.  A  
          total of $749,311 in grants were awarded.  

          Baybio, the California Healthcare Institute, and others write in  
          support that California is a leader in neurological and SCI  
          research.  Baybio further states in support that if we are to  
          maintain our prominence in this field of research, additional  
          funding for SCI research to replace GF contributions must be  
          found or we risk losing the matching funds and other grants that  
          we successfully attracted in the recent past.  According to  
          supporters, many discoveries supported by the Roman Reed Fund  
          are in the pipeline toward clinical translation including:  1)  
          the world's first clinical trial for stem cells for SCI; 2) a  
          treatment initially developed for SCI in clinical trials for  
          inflammatory bowel disease; and, 3) new surgical techniques  
          developed to treat people with nerve injuries.  

          The California Catholic Conference writes in opposition that  
          although recent amendments have shifted the funding from traffic  
          fines to the GF, this bill continues the unfortunate policy of  
          spending money on speculative research.  This opposition points  
          out that at a time in which we have cut funding for our state's  
          safety net-upon which our poor and vulnerable Californians  
          rely-it is highly inappropriate to divert money to University  
          researchers. 


           Analysis Prepared by  :    Marjorie Swartz / HEALTH / (916)  
          319-2097 


                                                               FN: 0002228 








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