BILL ANALYSIS                                                                                                                                                                                                    �



                                                                  SB 205
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          Date of Hearing:  June 25, 2013

                            ASSEMBLY COMMITTEE ON HEALTH
                                 Richard Pan, Chair
                    SB 205 (Corbett) - As Amended:  April 24, 2013

           SENATE VOTE  :  23-9
           
          SUBJECT  :  Prescription drugs:  labeling.

           SUMMARY  :  Requires the following information that is currently  
          required to be included on the label of a prescription container  
          to be printed in 12-point sans serif typeface: 1) The  
          manufacturer's trade or generic name of the drug and the name of  
          the manufacturer, as specified; 2) Directions for the use of the  
          drug; 3) Name of the patient or patients; 4) Strength of the  
          drug or drugs dispensed; and, 5) The condition or purpose for  
          which the drug was prescribed if the condition or purpose is  
          indicated on the prescription.  Makes other technical and  
          clarifying changes. 

           EXISTING LAW  :  

          1)Provides for the practice of pharmacy and the licensing and  
            regulation of pharmacies and pharmacists by the Board of  
            Pharmacy (Board) within the Department of Consumer Affairs.

          2)Specifies certain requirements regarding the dispensing and  
            furnishing of dangerous drugs and devices and prohibits a  
            person from furnishing any dangerous drug or device except as  
            prescribed by a physician, dentist, podiatrist, optometrist,  
            or veterinarian.

          3)Requires that each prescription dispensed by a pharmacist must  
            be in a container meeting state and federal specifications and  
            correctly labeled, as specified, including:

             a)   Unless otherwise ordered by the prescriber, the  
               manufacturer's trade name of the drug or the generic name  
               and the name of the manufacturer, as specified;
             b)   The directions for the use of the drug;
             c)   The name of the patient or patients;
             d)   The name of the prescriber, as specified;
             e)   The date of issue;
             f)   The name and address of the pharmacy and prescription  








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               number or other means of identifying the prescription;
             g)   The strength of the drug or drugs dispensed;
             h)   The quantity of the drug or drugs dispensed;
             i)   The expiration date of the effectiveness of the drug  
               dispensed;
             j)   The condition or purpose for which the drug was  
               prescribed if the condition or purpose is indicated on the  
               prescription; and,
             aa)  The physical description of the dispensed medication,  
               including its color, shape, and any identification code  
               that appears on the tablets or capsules.



           EXISTING REGULATIONS  :

          1)Requires labels on drug containers dispensed to patients in  
            California to conform to the following format:

             a)   Each of the following must be clustered into one area of  
               the label that comprises at least 50% of the label and be  
               printed in at least 10-point sans serif typeface, or, if  
               requested by the consumer, at least a 12-point typeface,  
               and listed in the following order:

               i)     Name of the patient;
               ii)    Name of the drug and strength of the drug;
               iii)   Directions for the use of the drug; and, 
               iv)    The condition or purpose for which the drug was  
                 prescribed if the condition or purpose is indicated on  
                 the prescription.

             b)   Requires for added emphasis, the label to highlight in  
               bold typeface or color, or use blank space to set off the  
               items listed in 1)a) above.

             c)   Requires the remaining elements that are required to be  
               printed on a label, as well as any other items of  
               information appearing on the label or the container, to be  
               printed so as not to interfere with the legibility or  
               emphasis of the primary elements specified in 1)a) above.  

          2)Requires the Board, by October 1, 2011, and updated as  
            necessary, to publish on its Website translation of specified  
            directions for use into at least five languages other than  








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            English, to facilitate their use by California pharmacies.   
            Specifies phrases that are required to be used for  directions  
            for use  , including:

             a)   Take 1 [insert appropriate dosage form] at bedtime;
             b)   Take 1 [insert appropriate dosage form] in the morning;
             c)   Take 1 [insert appropriate dosage form] in the morning,  
               and Take 1 [insert appropriate dosage form] at bedtime;
             d)   Take 1 [insert appropriate dosage form] in the morning,  
               1 [insert appropriate dosage form] at noon, and l [insert  
               appropriate dosage form] in the evening; or,
             e)   If you have pain, take [insert appropriate dosage form]  
               at a time. Wait at least __ hours before taking again. Do  
               not take more than [appropriate dosage form] in one day.

          3)Requires the Board to collect and publish on its Website  
            examples of labels conforming to these requirements, to aid  
            pharmacies in label design and compliance.

          4)Requires a pharmacy to have policies and procedures in place  
            to help patients with limited or no English proficiency  
            understand the information on the label as specified in 1) a)  
            above in the patient's language.  Requires the pharmacy's  
            policies and procedures to be specified in writing and to  
            include, at a minimum, the selected means to identify the  
            patient's language and to provide interpretive services in the  
            patient's language.  Requires the pharmacy, at a minimum, to  
            provide interpretive services in the patient's language, if  
            interpretive services in such language are available, during  
            all hours that the pharmacy is open, either in person by  
            pharmacy staff or by use of a third-party interpretive service  
            available by telephone at or adjacent to the pharmacy counter.
           FISCAL EFFECT  :  According to the Senate Appropriations  
          Committee, "One-time costs of about $75,000 to update  
          regulations and provide information to pharmacies by the Board  
          (Pharmacy Board Contingent Fund)."

           COMMENTS  :

           1)PURPOSE OF THIS BILL  .  According to the author, "seniors are  
            having difficulty reading the small print on their  
            prescription labels and, for those who take multiple  
            medications, their inability to read the label puts them in  
            serious danger."  The author states that among adults 65 years  
            of age or older, 40% take five to nine medications and 18%  








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            take 10 or more medications and that taking these incorrectly  
            or mixed with other medications can cause adverse drug events  
            that can lead to injury and death.  The author also notes that  
            The New England Journal of Medicine estimates that between  
            2007 and 2009, there were more than 260,000 emergency room  
            visits for adverse drug events in U.S. adults 65 years of age  
            or older.  Of those, almost 100,000 required emergency  
            hospitalizations, and nearly two-thirds of those  
            hospitalizations were due to unintentional overdoses.   The  
            author points out that making prescription medical container  
            labels easier for patients to read is a simple way to help  
            avoid dosing or medication errors due to a patient's inability  
            to read the label.  

           2)BACKGROUND  .  

              a)   Medication Errors  .  SCR 49 (Speier), Resolution Chapter  
               123, Statutes of 2005, established the Medication Errors  
               Panel (Panel) which published a report in March 2007  
               entitled, "Prescription for Improving Patient Safety:  
               Addressing Medication Errors."  The report listed six  
               general goals to reduce medication errors.  Under each goal  
               were recommendations (12 in all) and methods to accomplish  
               each recommendation.  The Panel report states that "the  
               information that consumers need to know about their  
               medication is often complex and may include unfamiliar  
               language or concepts.  Expecting a consumer to retain all  
               the pertinent knowledge from a brief verbal encounter may  
               not be reasonable in many instances."  Although the Panel  
               did not come to consensus on the most important subset of  
               consumers that are at "high risk" for medication errors, it  
               did acknowledge that there are a variety of factors which  
               may increase an individual's risk for experiencing a  
               medication error.  These include: i) low health literacy;  
               ii) limited English proficiency; iii) cultural incongruence  
               with healthcare providers; iv) physical, cognitive, and/or  
               other impairments that make understanding and/or complying  
               with medication instructions difficult; v) age at either  
               end of the age spectrum (the variability of a medication's  
               response, metabolism, and dose increases in children and  
               seniors); vi) multiple medications; vii) multiple  
               prescribers; viii) non-prescription medication use  
               (including herbals, dietary supplements, alcohol, and  
               tobacco); and, ix) medication procurement from more than  
               one pharmacy including mail-order. The Panel did state that  








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               these factors must be taken into consideration in the  
               development of any consumer education efforts.  

             One bill that was pursued in response to the Panel report was  
               SB 472 (Corbett), Chapter 470, Statutes of 2007.  SB 472  
               established the California Patient Medication Safety Act,  
               which requires the Board to promulgate regulations on or  
               before January 1, 2011, that require a standardized,  
               patient-centered, prescription drug label on all  
               prescription medicine dispensed to patients.  Additionally,  
               the Board was required to report to the Legislature by  
               January 1, 2010, on its progress in implementing these  
               regulations.  This bill is a follow-up to SB 472.

              b)   Report to the Legislature on the Implementation of SB  
               472  .  Pursuant to SB 472, the Board submitted its report  
               entitled, "Prescription Drugs: Labeling Requirements" to  
               the Legislature in January 2010.  The report indicated the  
               steps the Board took prior to adopting the final  
               regulations to implement SB 472.  Specifically, the Board  
               established a "SB 472 Medication Label Subcommittee" in  
               January 2008 to conduct public forums and to work with  
               organizations and individuals to develop recommendations to  
               implement the provisions of the law to establish a  
               patient-centered prescription drug label.  In May 2008, the  
               Board developed an open-ended prescription label survey for  
               distribution at public outreach events.  A total of 606  
               consumers completed the surveys.  Specifically, when asked  
               what to change on the prescription label, 30.1% responded  
               that print should be larger or darker; 24.5% indicated  
               nothing needs to be changed on the label; and, 12%  
               responded that the purpose of the drug must be included.   
               The Board considered testimony and information provided  
               from the public, the pharmaceutical industry, pharmacy  
               professionals, and literacy subject matter experts on  
               medical literacy research, improved directions for use,  
               improved font types and sizes, the placement of information  
               that is patient-centered, the needs of patients with  
               limited English proficiency, the needs of senior citizens,  
               and technology requirements necessary to implement the  
               standards developed.  Board members were also provided with  
               research articles on designing patient-centered labels.  In  
               2009, the Board discussed the requirements of the  
               regulation at regularly scheduled meetings, and the final  
               regulations were adopted in 2010.  








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              c)   Board Regulations on Font Size  .  Regulations adopted by  
               the Board in  2010  which took effect on January 1, 2011,  
               entitled Patient-Centered Labels for Prescription Drug  
               Containers, require a standardized, patient-centered  
               prescription drug label on all prescriptions dispensed to  
               patients.  Among other requirements, the regulations  
               require that the:  i) name of the patient; ii) name of the  
               drug and strength of the drug, as specified, iii)  
               directions for the use of the drug; and, iv) the condition  
               or purpose for which the drug was prescribed if the  
               condition or purpose is indicated on the prescription be  
               clustered into one area of the label that comprises at  
               least 50% of the label.  These items must also be printed  
               in at least a 10-point sans serif typeface, or if  requested   
               by the consumer, at least a  12 point  type face.  For added  
               emphasis and to set off such items, they are required to be  
               highlighted in bold typeface or color or use blank space.   
               All other items that are additionally required to appear on  
               a label are required to be printed so as not to interfere  
               with the legibility or emphasis of these items and may  
               appear in any style, font, and size typeface.   
              
              d)   Consumer Surveys Regarding Prescription Container  
               Labels  .  At the Board's April 2013 meeting, the Board's  
               Communication and Public Education Committee reported on  
               the results of surveys it conducted regarding prescription  
               container labels.  An electronic version of the survey was  
               sent to several consumer groups including AARP, Consumers  
               Union, and the California Pan Ethnic Health Network  
               (CPEHN), who in turn distributed it to their ListServe  
               contacts.  The survey was also translated in Chinese and  
               Spanish by the Board and distributed by CPEHN to the  
               appropriate audiences.  The surveys were also distributed  
               and collected at local Senior Scam Stopper seminars  
               sponsored by the Contractors State License Board.  A total  
               of 1204 completed surveys were received by the Board.  A  
               sample of the survey is as follows:  When asked if  
               prescription labels are easy to read, 58% of those surveyed  
               in English responded yes; 40% responded yes in Chinese; 35%  
               responded yes in Spanish; while 42% responded no in  
               English; 10% in Chinese; and, 62% in Spanish.  When asked  
               what information on the label was most important, 49%  
               responded directions for use and clear dosing instructions;  
               when asked what changes would make the labels better, 26%  








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               responded larger font; and, when asked what information  
               could be improved 7% responded larger font.

             Additionally, the Board conducted 767 patient-centered  
               labeling inspections of chain stores, community pharmacies,  
               and clinics to measure compliance with regulations.  The  
               Board indicated that 70% of pharmacies are printing in  
               12-point font:

                ------------------------------------------------------------ 
               |Patient-Centered Label:          |  Chain  |Communit|Clinic |
               |                                 |  Store  |   y    |       |
               |---------------------------------+---------+--------+-------|
               |Compliant                        |   355   |  339   |   1   |
               |---------------------------------+---------+--------+-------|
               |Noncompliant                     |   13    |   67   |   7   |
               |---------------------------------+---------+--------+-------|
               |Corrections Issued               |   13    |   79   |7      |
                ------------------------------------------------------------ 

                ------------------------------------------------------------ 
               |The label is usually printed in: |  Chain  |Communit|Clinic |
               |                                 |  Store  |   y    |       |
               |---------------------------------+---------+--------+-------|
               |10 point font is the default     |   40    |   73   |   0   |
               |---------------------------------+---------+--------+-------|
               |12 point font is the default     |   280   |  161   |   1   |
               |---------------------------------+---------+--------+-------|
               |Both 10-point & 12-point font    |   47    |  138   |0      |
               |appear on the label              |         |        |       |
                ------------------------------------------------------------ 

              e)   Notice to Consumers  .  The Board also adopted regulations  
               to require every pharmacy to post in a conspicuous place a  
               notice informing consumers, among other information,  of  
               their right to ask for and receive from any pharmacy,  
               prescription drug labels in 12-point font and the  
               availability of interpreter services upon request at no  
               cost.  The pharmacy may post this notice in paper form or  
               on a video screen if the posted notice or video screen is  
               positioned so that a consumer can easily point to and touch  
               the statement identifying the language in which he or she  
               requests assistance.  Otherwise, the notice shall be made  
               available on a flyer or handout clearly visible from and  
               kept within easy reach of each counter in the pharmacy  








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               where dangerous drugs are dispensed or furnished.

           3)SUPPORT  .  The California Alliance for Retired Americans states  
            that seniors are having difficulty reading the small print on  
            their prescription labels, and for those who take multiple  
            medications, their inability to read the label puts them in  
            serious danger.  CPEHN states that research shows that 12  
            point font is a size that most consumers feel comfortable  
            with.  Paramedics Plus states that this bill would save lives  
            and would provide patients with accurate and readable  
            prescription labels.  

           4)OPPOSITION  .  The California Pharmacists Association and the  
            National Association of Chain Drug Stores indicate that while  
            they appreciate the intent of this bill, they believe the  
            changes are premature and would not provide any additional  
            benefits to consumers.  The existing Patient-Centered Labeling  
            Regulations are a product of months of discussion among the  
            Board, licensed pharmacists, patient advocacy groups, and  
            industry experts where every detail was scrutinized in  
            crafting each component of the regulation.  To their  
            knowledge, there is no data indicating that the existing  
            regulations are insufficient and could unintentionally  
            interfere with the accurate communication of instructions to  
            patients.  This opposition states that the Board will submit a  
            report to the Legislature this December on the labeling  
            requirements and before the Legislature overturns the  
            decisions of the Board, it is important to establish whether  
            there is a need for changes and the benefits to consumers.
           5)DOUBLE REFERRAL  .  This bill is double referred, should it pass  
            out of this Committee, it will be referred to the Assembly  
            Business, Professions & Consumer Protection Committee.

           6)RELATED LEGISLATION .  

             a)   AB 396 (Fox) requires that every prescription include a  
               legible, clear notice of the condition or purpose for which  
               the drug is prescribed, unless the patient or prescriber  
               requests that this information be omitted.  AB 396 also  
               requires that every prescription container be correctly  
               labeled to include that information, if so indicated on the  
               prescription, unless the patient or prescriber requests  
               that this information be omitted.  AB 396 is pending in the  
               Assembly Rules Committee.









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             b)   AB 1136 (Levine) requires a pharmacist, on and after  
               January 1, 2014, if a pharmacist exercising his or her  
               professional judgment determines that a drug may impair a  
               person's ability to operate a vehicle or vessel, to include  
               a written label on the drug container indicating that the  
               drug may impair a person's ability to operate a vehicle or  
               vessel.  Permits the label to be printed on an auxiliary  
               label that is affixed to the prescription container.  AB  
               1136 is pending in the Senate Appropriations Committee.
               
             c)   SB 204 (Corbett) requires a pharmacist to use  
               translations of the directions for use in non-English  
               languages published on the Board's Internet Website, as  
               applicable, when labeling a prescription container;  
               authorizes a pharmacist to translate the directions for use  
               into additional non-English languages if certified  
               translation services are utilized to complete the  
               additional translations.  SB 204 is pending in the Assembly  
               Health Committee.

             d)   SB 289 (Correa) makes it unlawful for a person to drive  
               a motor vehicle if his or her blood contains any detectable  
               amount of a drug classified in Schedules I, II, III, or IV  
               of the California Uniform Controlled Substance Act, unless  
               the drug was consumed in accordance with a valid  
               prescription issued to the person by a licensed health care  
               practitioner.  SB 289 is pending in the Senate Public  
               Safety Committee.

           7)PREVIOUS LEGISLATION  .  

             a)   SB 472 requires the Board to promulgate regulations that  
               require, on or before January 1, 2011, a standardized,  
               patient-centered, prescription drug label on all  
               prescription medication dispensed to patients in  
               California. 

             b)   AB 1276 (Karnette) of 2007 would have required  
               prescribers of medications to ask the patient whether to  
               indicate the intended purpose of the prescription on the  
               prescription's label.  AB 1276 died in Assembly Business  
               and Professions Committee.

             c)   SCR 49 established a panel to study the causes of  
               medication errors and recommend changes in the health care  








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               system that would reduce errors associated with the  
               delivery of prescription and over-the-counter medication to  
               consumers.

             d)   AB 657 (Karnette) of 2005 would have required  
               prescription labels to include the intended purpose of the  
               drug, if indicated on the prescription, and would have  
               required a physician, dentist, optometrist, podiatrist, and  
               other specified drug prescribers, to ask the patient, or  
               patient's representative whether to indicate the intended  
               purpose of the prescription on the label.  AB 657 died in  
               Senate Business, Professions and Economic Development  
               Committee. 

             e)   AB 288 (Mountjoy) of 2005 would have required the  
               prescription container to be labeled with the condition for  
               which the drug was prescribed, unless the patient,  
               physician, or a parent or legal guardian of a minor patient  
               requests that the information be omitted.  AB 288 died in  
               Assembly Health Committee. 

             f)   AB 2125 (Levine) of 2004 would have required a physician  
               and surgeon to indicate a patient's diagnosis on each  
               prescription, as specified, and would have required the  
               prescription label to include the condition for which the  
               drug was described, unless the patient directs the  
               pharmacist not to include this information on the label.   
               AB 2125 died in Assembly Health Committee. 

             g)   SB 292 (Speier), Chapter 544, Statutes of 2003, requires  
               prescription labels to include a physical description of  
               the drug, including the color, shape, and any  
               identification code that appears on the tablet or capsule.

             h)   AB 2099 (Epple), Chapter 397, Statutes of 1993, requires  
               that the condition for which the drug is being prescribed  
               must be included on the label if the patient requests that  
               information on the label.

           8)TECHNICAL AMENDMENT  .  The author has agreed to amend this bill  
            to delete the words "sans serif" and allow the use of any  
            12-point typeface.

           REGISTERED SUPPORT / OPPOSITION  :









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           Support 
           
          California Alliance for Retired Americans
          California Commission on Aging
          California Pan-Ethnic Health Network
          Paramedics Plus
          Pharmacists Planning Services, Inc.
          Vision y Compromiso
           
            Opposition 
           
          California Grocers Association
          California Pharmacists Association 
          National Association of Chain Drug Stores

           Analysis Prepared by  :    Rosielyn Pulmano / HEALTH / (916)  
          319-2097