BILL ANALYSIS                                                                                                                                                                                                    Ó



                                                                     AB 170


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          Date of Hearing:  May 13, 2015


                        ASSEMBLY COMMITTEE ON APPROPRIATIONS


                                 Jimmy Gomez, Chair


          AB  
          170 (Gatto) - As Amended April 30, 2015


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          Urgency:  No  State Mandated Local Program:  YesReimbursable:   
          Yes


          SUMMARY:


          This bill changes requirements related to the state's newborn  
          screening program to provide additional information about the  
          storage and use of newborn screening blood samples for research.  








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           Specifically, this bill:


          1)Requires the California Department of Public Health (CDPH) to  
            provide information about the newborn screening tests, and to  
            obtain a signed informational acknowledgment form for the  
            receipt of specified information by the parent or guardian of  
            a newborn child regarding the storage, retention, and use of  
            the newborn child's blood sample for medical research.  


          2)Modifies provisions related to the newborn screening program  
            fee, to allow the fee to be adjusted to meet the reasonable  
            costs of the program.


          3)Allows people to request their blood samples, or those of  
            their children, be destroyed or not used for research, and  
            requires CDPH to comply with those requests.


          4)Requires CDPH to prepare, provide, and distribute a single  
            page of specified informational materials, and a standard  
            informational acceptance form.


          5)Requires every birth attendant and every perinatal licensed  
            health facility to provide each pregnant woman a copy of the  
            informational materials and a copy of the standard  
            informational acceptance form, and requires the local  
            registrar of births to provide this information for births  
            outside licensed facilities.


          6)Requires a copy of the standard informational acceptance form  
            to be maintained with the medical records of the mother of the  
            newborn child.










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          FISCAL EFFECT:


          1)One-time costs of $120,000 to promulgate regulations (Genetic  
            Disease Testing Fund). 


          2)Annual costs of $550,000 (Genetic Disease Testing Fund) for  
            printing, storage, and distribution of forms, and staff to  
            provide technical support and enforce collection and submittal  
            of forms. If an increased number of requests to destroy  
            specimens is received, minor potential increased laboratory  
            staff costs would be incurred.


          


          COMMENTS:


          1)Purpose.  According to the author, newborn screening is one of  
            the great public health success stories in this country, but  
            what happens to the samples after the screening process is  
            completed raises serious and troubling questions of consent  
            and privacy. In the case of California and a handful of other  
            states, these samples are indefinitely stored in state  
            repositories and research is conducted using the samples.  The  
            author states that most parents are poorly informed, if at  
            all, about the storage and medical research of these samples.


          2)Genetic Disease Screening Program.  In 1966, California began  
            its newborn screening program with the testing of  
            phenylketonuria.  Since its creation, the program has been  
            expanded several times as new discoveries are made and tests  
            developed, and now screens for more than 70 disorders.   
            Diseases have been continually added through regulation and  
            legislation.








                                                                     AB 170


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            Current regulations permit a parent to decline the screening  
            test.  A parent must then sign a form that states that not  
            having the test done can result in serious illness or  
            permanent damage to their child.  It also states that the  
            parent must accept responsibility should this occur.


          3)California BioBank.  DPH maintains a large and diverse  
            biobank, the California Biobank Program, which houses over  
            17.5 million prenatal serum samples and newborn leftover blood  
            spots.  These samples were collected for testing by the  
            prenatal and newborn screening programs.  The program is an  
            internationally recognized public health asset because of its  
            large size and culturally, geographically and genetically  
            diverse population.  Current CDPH regulations allow parents to  
            request their child's specimen be destroyed or not used for  
            research; however, the option to opt out does not appear to be  
            particularly well-publicized 
          4)Support.  The American Federation of State, County and  
            Municipal Employees and the Council for Responsible Genetics  
            support this bill.  





          5)Opposition.  There was significant opposition to prior  
            versions of this bill that had more impact on the newborn  
            screening program.  The bill has been significantly amended to  
            address only increased information related to the storage of  
            blood spots and their use in research. According to the  
            author, all opposition except for the California Hospital  
            Association has submitted letters that they are neutral on the  
            current version.  
          
          6)Staff Comments.  This bill includes duplicative requirements  
            related to the production and distribution of information and  








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            forms.  Numerous provisions could be streamlined and  
            clarified. Additionally, staff notes there is a significant  
            administrative burden to obtain signed informational  
            acknowledgement forms related to approximately 500,000 births  
            annually.  It is unclear whether the collection of forms is  
            unclear whether these additional administrative costs will  
            result in a tangible benefit.  








          Analysis Prepared by:Lisa Murawski / APPR. / (916)  
          319-2081