BILL ANALYSIS                                                                                                                                                                                                    Ó






           ----------------------------------------------------------------- 
          |SENATE RULES COMMITTEE            |                       AB 2640|
          |Office of Senate Floor Analyses   |                              |
          |(916) 651-1520    Fax: (916)      |                              |
          |327-4478                          |                              |
           ----------------------------------------------------------------- 


                                   THIRD READING 


          Bill No:  AB 2640
          Author:   Gipson (D) 
          Amended:  8/15/16 in Senate
          Vote:     21 

           SENATE HEALTH COMMITTEE:  7-1, 6/29/16
           AYES:  Hernandez, Nguyen, Hall, Mitchell, Monning, Pan, Roth
           NOES:  Nielsen
           NO VOTE RECORDED:  Wolk

           SENATE APPROPRIATIONS COMMITTEE:  5-2, 8/11/16
           AYES:  Lara, Beall, Hill, McGuire, Mendoza
           NOES:  Bates, Nielsen

           ASSEMBLY FLOOR:  57-20, 6/1/16 - See last page for vote

           SUBJECT:   Public health:  HIV


          SOURCE:    AIDS Project Los Angeles 
                     Los Angeles LGBT Center

          DIGEST:   This bill requires a medical provider or a person  
          administering a HIV test, in the case that a patient that is  
          known to be at high risk for HIV infection tests negative for  
          HIV to provide written information about the methods that  
          prevent or reduce the risk of contracting HIV, including, but  
          not limited to, pre-exposure prophylaxes (PrEP) and  
          post-exposure prophylaxes (PEP), consistent with guidance of the  
          federal Centers for Disease Control and Prevention (CDC).

          ANALYSIS:    Existing law places certain requirements on the  
          information shared by medical providers with patients for HIV  








                                                                    AB 2640  
                                                                    Page  2


          testing, as specified. Requires the medical provider or other  
          person performing a HIV test, after the results of a test have  
          been received, to ensure that the patient receives timely  
          information and counseling, as appropriate, to explain the  
          results and the implications for the patient's health. If the  
          patient tests positive for HIV infection, the medical provider  
          or the person who administers the test is required to inform the  
          patient that there are numerous treatment options available and  
          identify follow-up testing and care that may be recommended,  
          including contact information for medical and psychological  
          services. If the patient tests negative for HIV infection and is  
          known to be at high risk for HIV infection, the medical provider  
          or the person who administers the test is required to advise the  
          patient of the need for periodic retesting, explain the  
          limitations of current testing technology and the current window  
          period for verification of results, and may offer prevention  
          counseling or a referral to prevention counseling. 
            
          This bill requires a medical provider or a person administering  
          a HIV test, in the case that a patient that is known to be at  
          high risk for HIV infection tests negative for HIV, to provide  
          written information about the effectiveness and safety of all  
          methods that prevent or reduce the risk of contracting HIV,  
          including, but not limited to, PrEP and PEP, consistent with  
          guidance of the CDC.
          
          Comments

          1)Author's statement.  According to the author, AB 2640 seeks to  
            reduce the spread of HIV and save the lives of individuals at  
            high risk of HIV exposure by providing them with information  
            about preventive medications during HIV post-test counseling.  
            In 2013, California was second among the 50 states in the  
            number of new HIV diagnoses, with approximately 5,000 new HIV  
            diagnoses. A 2015 survey of individuals at risk for HIV by the  
            California HIV/AIDS Research Program found that only 1 in 10  
            respondents had ever used PrEP. Although awareness of the  
            intervention was high among those who had never taken PrEP,  
            awareness was significantly lower among Black and Latino  
            respondents compared to white respondents. In addition, the  
            large majority of respondents indicated they had never talked  
            to their doctor or healthcare provider about PrEP. Considering  
            the high volume of new HIV infections being diagnosed in the  
            state of California and the low awareness of these  







                                                                    AB 2640  
                                                                    Page  3


            medications, it is critical that those being tested are aware  
            of PrEP and PEP medications.

          2)Background.  According to the CDC, more than 1.2 million  
            people in the U.S. are living with HIV infection, and 13% are  
            unaware of their infection.  Gay, bisexual, and men who have  
            sex with men (MSM), particularly young African American MSM,  
            are most seriously affected by HIV.  By race, African  
            Americans face the most severe burden of HIV. Over the past  
            decade, the number of people living with HIV has increased,  
            while the annual number of new HIV infections has remained  
            relatively stable.  Still, the pace of new infections  
            continues at far too high a level, particularly among certain  
            groups. An estimated 13,712 people with an AIDS diagnosis died  
            in 2012, and approximately 658,507 people in the U.S. with an  
            AIDS diagnosis have died overall.  The Department of Public  
            Health's (DPH) Office of AIDS (OA) estimates that  
            approximately 126,000 Californians are living with HIV, and of  
            these, 23,000 or 18% are unaware of their HIV status.  An  
            estimated 6,000 Californians are newly diagnosed with HIV each  
            year. People living with HIV/AIDS have an estimated life  
            expectancy of 32 years after infection and that number is  
            increasing.  According to the OA, with treatment costs  
            averaging around $23,000 per year, lifetime treatment is  
            currently estimated at around $740,000 or more per person.   
            With that estimate, the 6,000 new infections per year in  
            California will cost an estimated $4.5 billion to treat.  
            
          3)PrEP and PEP.  "Treatment as prevention" (TasP) refers to HIV  
            prevention methods that use antiretroviral treatment to  
            decrease the risk of HIV transmission.  According to the World  
            Health Organization, TasP needs to be considered as a key  
            element of combination HIV prevention and as a major part of  
            the solution to ending the HIV epidemic. Through TasP, people  
            living with HIV/AIDS use anti-retroviral (ARV) medications to  
            reduce their viral load (the amount of HIV in the body) to  
            undetectable levels.  With an undetectable viral load, the  
            amount of HIV in the body is so small it greatly reduces the  
            likelihood of passing the virus to another person.  Strict  
            adherence to TasP reduces the likelihood of transmission by up  
            to 96%.  PrEP is a new intervention that uses an established  
            ARV medication, Truvada to protect at-risk HIV-negative  
            individuals from HIV infection.  PrEP is different from PEP;  
            the medication is taken before possible exposure.  Daily PrEP  







                                                                    AB 2640  
                                                                    Page  4


            use can lower the risk of getting HIV from sex by more than  
            90% and from injection drug use by more than 70%.  Missing  
            doses reduces PrEP effectiveness.  Truvada is currently the  
            only FDA drug approved for HIV PrEP. PEP uses ARV medications  
            to prevent HIV from replicating and spreading through the body  
            after an exposure to the virus.  PEP is a short-term (28-day)  
            intervention and must be started within three days of an  
            exposure - sooner, if possible - to be effective.  PEP was  
            originally developed for occupational exposures, such as  
            needle-sticks in hospitals, but is also effective for sexual  
            exposures.  

          4)Research supporting PrEP use.  On May 14, 2014, the U.S.  
            Public Health Service released the first comprehensive  
            clinical practice guidelines for PrEP.  This followed the  
            earlier publication of brief interim guidelines that were  
            based on findings from several large national and  
            international clinical trials.  Those trials evaluated PrEP  
            among gay and bisexual men, heterosexual men and women, and  
            injection drug users.  All participants in the trials received  
            pills containing either PrEP or placebo, along with intensive  
            counseling on safe-sex behavior, regular testing for sexually  
            transmitted diseases, and a regular supply of condoms.  In all  
            of the studies, the risk of getting HIV infection was lower-up  
            to 92% lower-for participants who took the medicines  
            consistently than for those who did not take the medicines. 

          5)CDC guidelines.  The most recent federal guidelines for health  
            care providers recommend that PrEP be considered for people  
            who are HIV-negative and at substantial risk for HIV  
            infection.  For sexual transmission, this includes anyone who  
            is in an ongoing relationship with an HIV-positive partner.   
            It also includes anyone who is not in a mutually monogamous  
            relationship with a partner who recently tested HIV-negative,  
            and, is a gay or bisexual man who has had anal sex without a  
            condom or been diagnosed with asexually transmitted disease in  
            the past six months; or, a heterosexual man or woman who does  
            not regularly use condoms during sex with partners of unknown  
            HIV status who are at substantial risk of HIV infection (e.g.,  
            people who inject drugs or have bisexual male partners). For  
            people who inject drugs, this includes those who have injected  
            illicit drugs in past six months and who have shared injection  
            equipment or been in drug treatment for injection drug use in  
            the past six months.  Health care providers should also  







                                                                    AB 2640  
                                                                    Page  5


            discuss PrEP with heterosexual couples in which one partner is  
            HIV-positive and the other is HIV-negative as one of several  
            options to protect the partner who is HIV-negative during  
            conception and pregnancy.  The CDC is currently updating  
            recommendations about use of PEP for HIV prevention.
          
          6)DPH PrEP Navigator Services Program.  In the 2015-2016 Budget  
            Act, the California Legislature appropriated $2 million  
            annually (General Fund, $1.764 million in local assistance,  
            $236,000 for state support) to DPH to establish a PrEP  
            Navigator Services Program to "?ensure access for and serve  
            the most vulnerable Californians at high risk for HIV." The  
            primary client target for the PrEP Navigator Services Programs  
            are gay, bisexual, transgender, or other MSM, transgender  
            women who have sex with men, and partners of HIV-positive  
            people with a detectable viral load and/or inconsistent  
            antiretroviral use.  Special emphasis is to be placed on young  
            gay and bisexual men, young transgender women, and gay and  
            bisexual men and transgender women of color. The PrEP  
            Navigator Services Programs established through this funding  
            are meant to identify, conduct outreach, and provide  
            culturally competent services to target populations, provide  
            assistance to participants allowing them to access, enroll in,  
            and utilize insurance or patient assistance programs to pay  
            for PrEP, link to PrEP providers, and support adherence to  
            PrEP and PrEP-related follow-up participants.


          FISCAL EFFECT:   Appropriation:    No          Fiscal  
          Com.:YesLocal:   No


          According to the Senate Appropriations Committee: 

          1)Likely ongoing costs in the millions to low tens of millions  
            to provide PrEP and PEP to high-risk individuals enrolled in  
            Medi-Cal (General Fund and federal funds). Based on CDC  
            estimates for the number of individuals at high risk for HIV  
            infection, Senate Appropriations staff estimates that there  
            are about 150,000 individuals in the state that would meet CDC  
            guidelines for using PrEP or PEP. For each 1% of that  
            population that elects to begin taking PrEP, the proportional  
            cost to the Medi-Cal program to cover the cost of providing  
            PrEP would be about $4 million per year. (Costs for PEP would  







                                                                    AB 2640 
                                                                    Page  6


            be considerable lower, since it is only recommended for 28-day  
            use, as opposed to ongoing use for PrEP.)

          2)Unknown long-term savings to Medi-Cal and the Aids Drug  
            Assistance Program due to lower HIV infection rates (General  
            Fund and federal funds). To the extent that the bill does  
            result in lower HIV infection rates, there would be cost  
            savings to the Medi-Cal and Aids Drug Assistance Programs.  
            However, there are some factors that limit the potential cost  
            savings from the bill. First, it is not known how effective  
            greater knowledge and use of PrEP and PEP are at the  
            population level in reducing HIV infection. There are clinical  
            studies that show a very dramatic decline in HIV infections  
            amongst users of PrEP. Whether those findings would translate  
            to the larger population not part of a research study is  
            unknown. Second, the annual cost to provide PrEP is may not be  
            substantially less than the current cost to provide treatment  
            to HIV positive Medi-Cal beneficiaries. The cost that Medi-Cal  
            would pay for PreP is not public information. However, the New  
            York State Department of Public Health indicates that annual  
            costs range from $8,000 to $14,000 per year. Even assuming  
            that Medi-Cal receives significant discounts, the cost to  
            provide PreP is likely to be in the thousands per patient per  
            year. On the other hand, the current average annual cost of  
            care for an HIV positive Medi-Cal beneficiary is about $15,000  
            per year. 


          SUPPORT:   (Verified  8/12/16)


          AIDS Project Los Angeles (co-source)
          Los Angeles LGBT Center (co-source)
          Access Support Network
          Bienestar Human Services, Inc.
          Black AIDS Institute
          California Health+ Advocates
          California Life Sciences Association 
          City of West Hollywood
          Community Clinic Association of Los Angeles County
          Desert AIDS Project
          Equality California
          Free Speech Coalition
          Friends Community Center







                                                                    AB 2640  
                                                                    Page  7


          Gender Health Center
          JWCH Institute, Inc.
          Men's Health Foundation
          Our Family Coalition
          Positive Women's Network
          Project Inform
          San Diego LGBT Community Center
          San Francisco AIDS Foundation
          Tarzana Treatment Centers
          Transgender Law Center
          UCLA Center for Behavioral and Addiction Medicine


          OPPOSITION:  (Verified  8/15/16)


          AIDS Healthcare Foundation
          American College of Emergency Physicians, California Chapter


          ARGUMENTS IN SUPPORT: AIDS Project Los Angeles and the Los  
          Angeles LGBT Center are the co-sponsors of this bill and state  
          that awareness and use of PrEP and PEP among Californians at  
          risk for HIV remain extremely low.  The sponsors note that in  
          2015 the California HIV/AIDS Research Program conducted a survey  
          of young gay and bisexual men and found that only one in 10 had  
          ever taken PrEP, and although awareness of the intervention was  
          high overall, awareness was significantly lower among black and  
          Latino respondents compared to white respondents.  The sponsors  
          also note the majority of respondents lacked the information  
          needed to make a decision about using PrEP, did not know where  
          to access PrEP, and that few respondents had ever talked to  
          their doctor or healthcare provider about PrEP.  They conclude  
          it remains vital to ensure that all individuals at risk for HIV  
          receive accurate information about PrEP and PEP, particularly  
          highly-impacted communities of color. Numerous supporters state  
          that roughly 4,700 individuals are newly diagnosed with HIV in  
          California each year and PrEP/PEP are highly effective HIV  
          prevention interventions that could dramatically reduce new  
          infections. Supporters state that PrEP and PEP are key  
          components of the National HIV/AIDS Strategy, but awareness and  
          use of these interventions remain extremely low, and it is vital  
          to increase awareness and use of PrEP and PEP among communities  
          at risk for HIV. Equality California states that given the  







                                                                    AB 2640  
                                                                    Page  8


          effectiveness of PrEP and PEP, it is now critically important to  
          ensure that individuals receiving an HIV test are also provided  
          with accurate information about the benefits of these  
          interventions.  Bienestar Human Services writes that this bill  
          builds on AB 446, which established what information must be  
          provided to individuals during HIV post-test counseling,  
          including advising the individual of the need for periodic  
          retesting and explaining the limitations of current testing  
          technology. Bienstar states that given the effectiveness of PrEP  
          and PEP, it is now critically important to ensure that  
          individuals receiving an HIV test are also provided with  
          accurate information about the benefits these interventions.  
          California Health+ Advocates writes that California's clinics  
          are committed to keeping our patients healthy and this bill will  
          assist in this mission.                 
             
          ARGUMENTS IN OPPOSITION:  The AIDS Healthcare Foundation (AHF)  
          states that HIV screening is intended to mirror other screening  
          tests, which require simple consent only and which do not burden  
          the process with additional activities that may or may not be  
          necessary.  AHF also notes that guidelines for prevention and  
          risk reduction are fluid, based on the most recent advice from  
          the CDC and DPH, and that information to be shared must be  
          dictated by the needs and circumstances of the person being  
          tested.  Finally, AHF contends that recent changes to California  
          law that allowed for disclosure of a negative HIV test result on  
          a secure Web site already minimizes the interaction between the  
          tester and the test subject post-testing and makes the conveying  
          of any more than the most basic information in current law less  
          likely to be useful. 


          ASSEMBLY FLOOR:  57-20, 6/1/16
          AYES:  Alejo, Travis Allen, Atkins, Baker, Bloom, Bonilla,  
            Bonta, Brown, Burke, Calderon, Campos, Chau, Chiu, Chu,  
            Cooley, Cooper, Dababneh, Daly, Dodd, Eggman, Cristina Garcia,  
            Eduardo Garcia, Gatto, Gipson, Gomez, Gonzalez, Gordon, Gray,  
            Harper, Roger Hernández, Holden, Irwin, Jones-Sawyer, Levine,  
            Lopez, Low, Maienschein, Mayes, McCarty, Medina, Mullin,  
            Nazarian, O'Donnell, Quirk, Ridley-Thomas, Rodriguez, Salas,  
            Santiago, Mark Stone, Thurmond, Ting, Waldron, Weber, Wilk,  
            Williams, Wood, Rendon
          NOES:  Achadjian, Arambula, Bigelow, Brough, Chávez, Dahle, Beth  
            Gaines, Gallagher, Grove, Jones, Kim, Lackey, Linder, Mathis,  







                                                                    AB 2640  
                                                                    Page  9


            Melendez, Obernolte, Olsen, Patterson, Steinorth, Wagner
          NO VOTE RECORDED:  Chang, Frazier, Hadley

          Prepared by:Melanie Moreno / HEALTH / (916) 651-4111
          8/15/16 20:22:28


                                   ****  END  ****