BILL ANALYSIS                                                                                                                                                                                                    






                                 SENATE HEALTH
                               COMMITTEE ANALYSIS
                        Senator Elaine K. Alquist, Chair


          BILL NO:       AB 417                                       
          A
          AUTHOR:        Beall                                        
          B
          AMENDED:       May 19, 2009
          HEARING DATE:  July 8, 2009                                 
          4
          CONSULTANT:                                                 
          1
          Bain/                                                       
          7
                                        

                                     SUBJECT
                                         
                Medi-Cal Drug Treatment Program:  buprenorphine 

                                     SUMMARY  

          Requires buprenorphine services to be included within the  
          scope of Drug Medi-Cal services, subject to certain  
          requirements (buprenorphine is used to treat opioid  
          addiction).  Additionally, this bill requires a separate  
          narcotic replacement therapy dosing fee for buprenorphine  
          to be established.  This bill would not be implemented if  
          the Department of Health Care Services (DHCS) determines  
          the provisions of this bill require an unbundling of Drug  
          Medi-Cal reimbursement rates.

                             CHANGES TO EXISTING LAW  

          Existing law:
          Existing law establishes the Medi-Cal Program, which is  
          administered by DHCS and under which qualified low-income  
          persons receive health care benefits.  The schedule of  
          benefits available under Medi-Cal includes the purchase of  
          prescribed drugs, subject to the Medi-Cal List of Contract  
          Drugs and utilization controls.

          Existing law establishes the Medi-Cal Drug Treatment  
          Program (Drug Medi-Cal), under which each county enters  
                                                         Continued---



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          into contracts with the Department of Alcohol and Drug  
          Programs (DADP) for the provision of various drug treatment  
          services to Medi-Cal recipients, or DADP directly arranges  
          for the provision of these services if a county elects not  
          to do so.

          Existing law requires DADP to establish a narcotic  
          replacement therapy dosing fee for methadone and  
          levo-alphacetylmethadol (LAAM), requires narcotic treatment  
          programs (NTPs) to be reimbursed for the ingredient costs  
          of methadone or LAAM dispensed to Medi-Cal beneficiaries,  
          and requires reimbursement for narcotic replacement therapy  
          dosing and ancillary services provided by NTPs to be based  
          on a per capita uniform statewide daily reimbursement rate  
          for each individual patient, as established by DADP, in  
          consultation with DHCS.  Existing law requires the uniform  
          statewide daily reimbursement rate for narcotic replacement  
          therapy dosing and ancillary services to be based upon,  
          where available and appropriate, specified factors. 

          Existing requires DADP to establish a program for the  
          operation and regulation of an office-based NTP.  An  
          office-based NTP established must meet either of the  
          following conditions:

           Hold a primary NTP license; or
           Be affiliated and associated with a primary licensed NTP.  
            An office-based NTP meeting this requirement is not  
            required to have a license separate from the primary  
            licensed NTP with which it is affiliated and associated.

          Existing law provides the following services under Drug  
          Medi-Cal administered by DADP and to the extent consistent  
          with state and federal law: 

           NTP services (admission, physical evaluation and  
            diagnosis, drug screening, pregnancy tests, narcotic  
            replacement therapy dosing, intake assessment, treatment  
            planning, and counseling services);
           Day care rehabilitative services;
           Perinatal residential services for pregnant women and  
            women in the postpartum period;
           Naltrexone services; and,
           Outpatient drug-free services.





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          This bill:
          This bill requires buprenorphine services to be included  
          within the scope of Drug Medi-Cal Services, but only if  
          buprenorphine is:

           Administered by a licensed NTP and ordered or prescribed  
            by a physician who complies with federal requirements and  
            works under the license of the NTP; or,

           Prescribed by a physician who complies with federal  
            requirements, but does not work under the license of an  
            NTP.

          This bill requires the Department of Drug and Alcohol  
          Programs (DADP) to establish a separate narcotic  
          replacement therapy dosing fee for buprenorphine.  DADP  
          must, for purposes of establishing the dosing fee for  
          buprenorphine, LAAM, and methadone, include comprehensive  
          services that include physician and medication services.

          This bill adds buprenorphine to the list of controlled  
          substances authorized for use in replacement narcotic  
          therapy by licensed NTPs.

          This bill defines "buprenorphine" as buprenorphine or  
          buprenorphine combination products approved by the federal  
          Food and Drug Administration (FDA) for maintenance or  
          detoxification of opioid dependence. 

          This bill prohibits its provisions from being implemented  
          if the director of DHCS determines these provisions would  
          require an unbundling of Drug Medi-Cal reimbursement rates,  
          and states legislative intent that this bill not result in  
          the unbundling            of Drug Medi-Cal Services  
          reimbursement rates.
          
                                  FISCAL IMPACT  

          According to the Assembly Appropriations Committee:

           If 10 percent of current methadone patients convert to  
            buprenorphine and their time on the drug averages three  
            months (as evidence suggests) rather than the much longer  
            treatment using methadone, the savings to the Drug  
            Medi-Cal Program would be in excess of $20 million ($10  




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            million General Fund).

           Workload associated with adding buprenorphine to the  
            current bundled rate should be minor, likely less than  
            $100,000.

                            BACKGROUND AND DISCUSSION  

          According to the author, this bill requires DADP to allow  
          for the use of buprenorphine treatment in NTPs.  Under  
          current law, NTPs are only eligible to claim reimbursement  
          for two medication-assisted treatments:  methadone and  
          LAAM.  LAAM is no longer manufactured, leaving methadone as  
          the only treatment option.  Buprenorphine was approved for  
          use in the treatment of opioid addiction in 2002 through  
          federal law, but DADP has not authorized reimbursement for  
          buprenorphine therapy in the Drug Medi-Cal Program.  The  
          unavailability of buprenorphine as a therapy option has  
          created a two-tiered system of care that the author argues  
          prevents providers from utilizing the most advanced  
          medication available.  

          The author states substance abuse exacts a devastating toll  
          in California, ruining lives, destroying families, and  
          devouring tax dollars.  According to the author, more than  
          70 percent of the cost associated with prison, parole,  
          local criminal adjudication, and child welfare are related  
          to untreated alcohol and other drug abuse problems.  The  
          author continues that in 2005 alone, California spent $44  
          billion rectifying the fallout from drug and alcohol abuse.  
           Research shows that substance abuse treatment is  
          effective, but is most effective when tailored to meet the  
          needs of the individual, and this bill adds an additional  
          option for treating substance abuse.

          Background on buprenorphine.  
          Prescription pain relievers like morphine, oxycodone, and  
          codeine are opioids.  Buprenorphine is used to treat  
          addiction to opioids by preventing withdrawal symptoms so  
          that a person can stop taking the opioid drug to which he  
          or she is addicted.

          In October 2002, the FDA approved two buprenorphine  
          products (Subutex and Suboxone) for use in opioid addiction  
          treatment.  Subutex and Suboxone were the first narcotic  




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          drugs available for the treatment of opiate dependence that  
          can be prescribed in an office setting under the federal  
          Drug Addiction Treatment Act (DATA) of 2000.  Prior to  
          DATA, opiate dependence treatments like methadone could be  
          dispensed in a limited number of clinics that specialize in  
          addiction treatment.  Under DATA, medications for the  
          treatment of opiate dependence are subject to less  
          restrictive controls.  Buprenorphine can be prescribed in  
          an office-based setting by specially qualified physicians,  
          and patients can obtain a 30-day supply from a pharmacy.   
          Under federal regulations, physicians who prescribe  
          buprenorphine must have a Drug Enforcement Agency number,  
          must successfully complete appropriate training, and must  
          have a buprenorphine waiver from the Center for Substance  
          Abuse Treatment (CSAT).  According to the Substance Abuse  
          and Mental Health Services Administration Website, there  
          are 1,159 physicians and 182 treatment programs in  
          California authorized to treat opioid addiction with  
          buprenorphine.

          Subutex and Suboxone are available through "regular"  
          Medi-Cal (not Drug Medi-Cal) with a treatment authorization  
          request, but there is not a reimbursement rate amount  
          established through Drug Medi-Cal administered by DADP.  In  
          2008, there were 3,764 prescriptions dispensed in Medi-Cal  
          for the two medications, with a total amount paid of  
          $890,505.  The manufacturer of the drugs indicates the  
          federal patent protection for these two medications ends in  
          October 2009.

          2004 Legislative Analyst's Office Report on Drug Medi-Cal.   

          In its analysis of the Governor's proposed 2004-05 budget,  
          the Legislative Analyst's Office (LAO) recommended as part  
          of its proposal to contain the fast-growing state cost for  
          methadone services, that the Legislature consider  
          integrating buprenorphine into Drug Medi-Cal.  The LAO  
          indicated it was advised that, for many clients (although  
          by no means all), buprenorphine treatment offers some  
          advantages over methadone.  It can be distributed in tablet  
          form through the offices of qualified physicians instead of  
          just through narcotic treatment clinics, potentially making  
          these services more widely accessible to clients without  
          the stigma perceived from visiting a drug-treatment clinic.  
           Formulation of the drug in a combination with another  




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          medication called naloxone lowers the risk that the drug  
          itself can be abused, as has sometimes been the case for  
          methadone.  The LAO states published medical evaluations  
          show that it is less toxic and poses fewer medical risks to  
          clients, and that treatment can often be phased out in a  
          shorter period of time than methadone.  The LAO indicates  
          that, while the cost per dose for buprenorphine is higher  
          than for methadone, the overall cost per treatment episode  
          can be lower for buprenorphine, due primarily to the  
          shorter duration of treatment. 

          The LAO states that the Legislature has the option of  
          formally integrating the medication through statutory and  
          regulatory changes into both the regular Medi-Cal Program  
          and Drug Medi-Cal, and modifying state licensing and  
          certification procedures for treatment programs.  As part  
          of this change in approach, the LAO indicates that the  
          Legislature may wish to consider:

           Including counseling as a part of buprenorphine  
            treatment, due to evidence suggesting that counseling  
            reduces relapse rates of persons treated with the  
            medication;

           A "step therapy" approach by which buprenorphine would  
            ordinarily become the first method of treatment attempted  
            for narcotic addicts before other methods, such as  
            methadone, was attempted; and, 


           Phasing in a licensing requirement specifying that  
            narcotic treatment clinics establish a network of  
            qualified physicians sufficient to meet the needs of  
            their caseload of clients receiving buprenorphine  
            treatment.  The LAO indicates a delay of several years  
            before full implementation of such a rule would almost  
            certainly be necessary to ensure that a sufficient number  
            of physicians with the necessary qualifications were  
            available to clinics to manage the buprenorphine  
            caseload. 

          The LAO indicates the cost of a daily dose of buprenorphine  
          is relatively high compared that to methadone.  The LAO  
          states that the Medi-Cal Program is already able to obtain  
          rebates under federal and state law to lower the cost of  




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          the medication to the state, and the cost of the drug could  
          drop significantly when it could become available in  
          "generic" form. 

          Arguments in support
          Health care providers and drug treatment advocates argue  
          buprenorphine is a safe and affective alternative to  
          methadone for treating opioid dependence when used under  
          the supervision of a physician.  The County Alcohol and  
          Drug Program Administrators Association of California  
          (CADPAAC) writes in support that DADP has never authorized  
          a reimbursement code for buprenorphine therapy in  
          Drug-Medi-Cal, even though some private sector health plans  
          authorize coverage of this medication as an appropriate,  
          successful, and effective treatment.  CADPAAC argues the  
          unavailability of the therapy in Drug Medi-Cal leads to a  
          two-tiered system of care, and limits providers from using  
          the most effective therapies for treating opioid addiction.  
           

          Related bills
          AB 1055 (Chesbro) would allow physicians who meet the  
          criteria in federal DATA to engage in office-based  
          treatment of opioid dependence, provided the physician is  
          not affiliated or associated with a licensed NTP.  AB 1055  
          would also expand the definition of an "alcoholism or drug  
          abuse recovery or treatment facility" to include a premise,  
          place, or building that provides 24-hour services that do  
          not require a health facility license to adults who are  
          recovering from problems related to alcohol, drug, or  
          alcohol and drug misuse or abuse and who need alcohol,  
          drug, or alcohol and drug recovery treatment or  
          detoxification services, and which may include, at the sole  
          discretion of the facility, detoxification services  
          assisted by licensed physicians.  AB 1055 was held on the  
          Assembly Appropriations suspense file.

          Prior legislation 
          SB 1838 (Chesbro), Chapter 862, Statutes of 2004, among  
          other provisions, authorizes for use in replacement  
          narcotic therapy by licensed NTPs the following controlled  
          substances:  methadone, LAAM, buprenorphine products or  
          combination products approved by the FDA for maintenance or  
          detoxification of opioid dependence, and any other  
          federally approved controlled substances used for the  




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          purpose of narcotic replacement treatment.

                                     COMMENTS
           
          1.Prescribing buprenorphine outside NTP.  This bill  
            includes buprenorphine within Drug Medi-Cal services  
            under two circumstances:  (a) when buprenorphine services  
            are administered by a licensed NTP and they are ordered  
            or prescribed by a physician who complies with federal  
            requirements and works under the license of the NTP; and  
            (b) the buprenorphine services are prescribed by a  
            physician who complies with federal requirements, but  
            does not work under the license of an NTP (e.g., when the  
            drug is prescribed outside of an NTP).  

          DADP, which administers Drug Medi-Cal, indicates the second  
            provision providing coverage of buprenorphine for a  
            physician who does not work under the license of an NTP  
            would require it to oversee the prescribing and  
            dispensing practices of individual physicians who it does  
            not currently have billing relationship or regulatory  
            oversight.  

                                  PRIOR ACTIONS

           Assembly Floor:     78-0
          Assembly Appropriations:12-0
          Assembly Health:    18-0

                                    POSITIONS  
                                        
          Support:   California Association of Alcohol and Drug  
          Program Executives, Inc.
                     California Medical Association
                 California Opioid Maintenance Providers
                     County Alcohol and Drug Program Administrators  
          Association of California

          Support (prior version):
                     American Federation of State, County and  
          Municipal Employees, AFL-CIO
                     California Psychiatric Association
                            Drug Policy Alliance

          Oppose:    None received




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