BILL ANALYSIS                                                                                                                                                                                                    







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        |Hearing Date:June 28, 2010         |Bill No:AB                         |
        |                                   |549                                |
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                      SENATE COMMITTEE ON BUSINESS, PROFESSIONS 
                               AND ECONOMIC DEVELOPMENT
                         Senator Gloria Negrete McLeod, Chair

                         Bill No:        AB 549Author:Furutani
                        As Amended:June 17, 2010 Fiscal:   Yes

        
        SUBJECT:   Healing arts:  Licensure:  clinical laboratory personnel. 
        
        SUMMARY:  Includes clinical biochemical geneticist in the list of  
        clinical laboratory personnel that are eligible for licensure by the  
        Department of Public Health (DPH).  Requires DPH to issue a temporary  
        license to a histocompatibility laboratory director, and other  
        specified clinical laboratory personnel within 30 days of receiving a  
        completed application.  Requires DPH to adopt emergency regulations  
        creating a trainee license category, as specified.

        Existing law:
        
        1)Establishes in federal law, the Clinical Laboratory Improvement  
          Amendments of 1988 (CLIA), which regulates laboratories when  
          performing testing on human specimens and includes laboratory  
          standards for proficiency testing, facility administration,  
          personnel qualifications, and quality control.  Applies  
          standards to all settings, including commercial, hospital, or  
          physician office laboratories.

        2)Establishes within the Department of Public Health (DPH) the  
          Laboratory Field Services (LFS) which provides for licensing and  
          registration services for clinical laboratories, and laboratory  
          personnel, as specified.

        3)Defines a clinical laboratory as any establishment or  
          institution operated for the performance of clinical laboratory  
          tests or examinations, or the practical application of clinical  
          laboratory sciences.  

        4)Defines a clinical laboratory test or examination as the  





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          detection, identification, measurement, evaluation, correlation,  
          monitoring, and reporting of any particular analyte, entity, or  
          substance within a biological specimen for the purpose of  
          obtaining scientific data which may be used as an aid to  
          ascertain the presence, progress, and source of a disease or  
          physiological condition in a human being, or used as an aid in  
          the prevention, prognosis, monitoring, or treatment of a  
          physiological or pathological condition in a human being, or for  
          the performance of nondiagnostic tests for assessing the health  
          of an individual.

        5)Provides that a clinical chemist, microbiologist, toxicologist,  
          genetic molecular biologist, cytogeneticist or oral and  
          maxillofacial pathologist is any person licensed by DPH to  
          engage in, or supervise others engaged in, clinical laboratory  
          practice limited to his or her area of specialization or to  
          direct a clinical laboratory, or portion thereof, limited to his  
          or her area of specialization.  Specifies requirements for  
          licensure of these clinical laboratory personnel, including  
          requirements in training, education and experience.  States that  
          the application and renewal fees for these laboratory personnel  
          are $63 commencing on July 1, 1983.

        6)States that a histocompatibility laboratory director means a  
          physician and surgeon licensed to practice medicine or a  
          licensed bioanalyst, and qualified to serve as a laboratory  
          director, as specified; or a person who has earned a doctoral  
          degree in a biological science, who has completed, subsequent to  
          graduation, four years of experience in immunology, two of which  
          have been in histocompatibility testing.

        7)States that on and after January 1, 2007, to be eligible for  
          licensure as a histocompatibility laboratory director, an  
          applicant who is not a licensed physician and surgeon or  
          bioanalyst must provide evidence of satisfactory performance on  
          a written examination in histocompatibility, as specified.

        8)States that a person who is licensed as a histocompatibility  
          laboratory director and qualified under CLIA may perform  
          clinical laboratory tests or examinations classified as of high  
          complexity under CLIA, and any clinical laboratory test or  
          examination classified as waived or of moderate complexity under  
          CLIA.

        9)Establishes the Clinical Laboratory Improvement Fund into which  
          fees collected by DPH from clinical laboratories are deposited  





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          and used for the purpose of licensing, registration,  
          certification, inspection, or other activities relating to the  
          regulation of clinical laboratories.

        This bill:

        1) Includes clinical biochemical geneticist in the list of clinical  
           laboratory personnel that are eligible for licensure by the DPH to  
           engage in, supervise others, or direct a clinical laboratory  
           practice, as specified.

        2) Defines biochemical genetics as the techniques used to analyze  
           human proteins and certain metabolites from physiological samples  
           for the primary purpose of detecting inborn errors of metabolism,  
           heritable genotypes or gene products of genetic variations or  
           mutations for clinical purposes that include, but are not limited  
           to, the use of these test results to aid in the evaluation and  
           diagnosis of patients, predicting risk of disease, identifying  
           carriers, and establishing prenatal or clinical diagnoses or  
           prognoses in individuals, families, and populations.

        3) Requires DPH, within 30 days of receiving a completed application,  
           to issue a  temporary license  to any applicant seeking licensure as  
           a histocompatibility laboratory director, clinical chemist,  
           microbiologist, toxicologist, molecular biologist, cytogeneticist,  
           or biochemical geneticist, provided that the applicant meets the  
           following requirements:

             a)     The applicant has at least two years of experience as a  
               histocompatibility laboratory director in another state or in  
               Canada. 

             b)     The applicant has board certification from the American  
               Board of Histocompatibility and Immunogenetics.

        4) States that a temporary license issued pursuant to item # 3) above,  
           shall remain valid until DPH completes evaluating and processing  
           the applicant's completed application, the applicant has passed any  
           required examinations, and DPH has issued a permanent license.   
           Provides that if the applicant fails to pass the required  
           examinations, DPH may revoke the temporary license upon notice to  
           the applicant sent by first-class mail.

        5) Requires DPH, no later than April 1, 2011, to adopt emergency  
           regulations creating a  trainee license  in the following licensed  
           categories: clinical chemistry, clinical microbiology, clinical  





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           toxicology, clinical molecular biology, clinical biochemical  
           genetics, and clinical cytogenetics, and as a clinical  
           histocompatibility and immunology laboratory director.  States that  
           the adoption of these emergency regulations shall be considered by  
           the Office of Administrative Law to be necessary to avoid serious  
           harm to the public health, safety, or general welfare.

        6) States that the trainee license for the personnel specified in item  
           # 5) above, applies to: 
        a) applicants holding an earned doctoral degree in a biological  
           science or field related to genetics from an accredited university;  
           and, b) who provide evidence of satisfactory performance on a  
           written examination in the area of specialty that is administered  
           by the American Board of Medical Genetics, the Canadian Council of  
           Medical Genetics, or the appropriate accrediting body for the area  
           of specialty for which the applicant is seeking licensure.  

        7) Provides that a formal letter, or other written documentation  
           issued by an accredited training program indicating that the  
           applicant has completed the program, and from a clinical laboratory  
           confirming the applicant's employment experience, shall constitute  
           sufficient evidence for the following licensed categories: clinical  
           chemistry, clinical microbiology, clinical toxicology, clinical  
           molecular biology, clinical biochemical genetics, and clinical  
           cytogenetics.  
        Requires these applicants to provide evidence of satisfactory  
           performance on a written examination in the applicant's specialty  
           or subspecialty administered by an appropriate accrediting body  
           recognized by DPH.  States that to constitute sufficient evidence,  
           formal letters or other documentation must be provided directly by  
           the examining agency or appropriate accrediting body to DPH.

        8) Requires DPH to maintain an expeditious process for licensing  
           applicants for licensure in clinical laboratory practice.  States  
           that application forms and instructions for each category of  
           licensure shall be posted on DPH's Internet Website.

        9) Requires DPH, within 30 calendar days after receiving an  
           application for licensure in clinical laboratory practice,  
           including a resubmission of an application, to notify the applicant  
           in writing, or by electronic mail that the application is complete  
           and shall be processed by DPH or that the application is  
           incomplete.  States that if the application is incomplete, DPH  
           shall specify in the notification the transcripts, board  
           certification, verification of training, or other documents  
           required to complete the application for licensure that have not  





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           been received by the department.

        10)Requires DPH to process each completed application within 90  
           calendar days following receipt of the completed application.

        11)States that an applicant for licensure in clinical laboratory  
           practice shall be eligible for any required examinations upon  
           notification by DPH that the applicant's application has been  
           approved.  Provides that an applicant shall be eligible for the  
           required examinations for 180 calendar days following the date  
           eligibility begins.  Requires that eligibility be extended for an  
           additional 180 calendar days if a required examination has not been  
           offered or scheduled by DPH within the original 180-day period.

        12)Applies existing laboratory personnel application and renewal fees  
           ($63) to biochemical geneticists.

        13)Makes other technical, non-substantive changes.

        FISCAL EFFECT:  According to the Assembly Appropriations Committee:

        1)Absorbable one-time fee-supported special fund costs to amend  
          current law regulations to accommodate 30 professionals statewide  
          who may become licensed in this highly specialized field.

        2)Unknown, likely absorbable one-time fee-supported special fund costs  
          for DPH to establish confirmation of employment experience by  
          national accrediting bodies.

        COMMENTS:
        
        1. Purpose.  According to the  City of Hope  , the Sponsor of this  
           measure, California faces a shortage of qualified clinical  
           laboratory scientists that could interpret and communicate results  
           to other professionals or to patients in highly complex labs in  
           specialized fields like genetics and histocompatibility.  As a  
           result of this shortage, clinical labs have to outsource to  
           laboratories in neighboring states, which is adding additional cost  
           and delaying the results.  This is detrimental to cancer centers  
           like City of Hope that deal with life threatening diseases and  
           require fast processing and interpretations of laboratory results.   
           Additionally, the City of Hope has identified several barriers to  
           licensing of highly specialized clinical laboratory personnel,  
           including lengthy delays in the processing of applications by DPH,  
           and the lack of provision for the issuance of a temporary license  
           pending approval by DPH.  Lastly, the City of Hope points out that  





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           the state currently does not have any regulations or licensing  
           program for biochemical geneticists, and although this is a  
           relatively small field, it is a highly complex category that needs  
           regulation.  
            
        2. Background.  

             a)     Biochemical Genetics.  According to the American Board of  
               Medical Genetics (ABMG), an organization that certifies  
               individuals and accredits training programs in the field of  
               human genetics, a clinical biochemical geneticist is an  
               individual with a U.S. or Canadian earned, or the equivalent of  
               an earned doctoral degree (M.D., D.O., Ph.D.) who can correctly  
               perform and interpret biochemical analyses relevant to the  
               diagnosis and management of human genetic diseases, and who  
               acts as a consultant regarding laboratory diagnosis of a broad  
               range of biochemical genetic disorders.  ABMG points out that  
               these requirements imply that the individual possesses the  
               following: the ability to supervise and direct the operations  
               of a clinical biochemical genetics diagnostic laboratory,  
               including technical expertise and knowledge in quality control  
               and quality assessment procedures; broad knowledge of (1) basic  
               biochemistry and genetics, 
             (2) the application of biochemical techniques to the diagnosis  
               and management of genetic diseases, and (3) the etiology,  
               pathogenesis, clinical manifestations, and management of human  
               inherited biochemical disorders; an understanding of the  
               heterogeneity, variability, and natural history of biochemical  
               genetic disorders; diagnostic and interpretive skills in a wide  
               range of biochemical genetic problems; and the ability to  
               communicate biochemical laboratory results in the capacity of  
               consultant to medical genetics professionals and other  
               clinicians, and directly to patients in concert with other  
               professional staff.

             b)     Clinical Laboratories.  According to DPH, there are  
               approximately 19,000 clinical laboratories in California, 3,000  
               of which are licensed laboratories performing moderate and/or  
               high complexity testing.  The remaining 12,000 are registered  
               labs performing waived tests and/or provider-performed  
               microscopy.  California's clinical laboratories are subject to  
               both federal and state oversight.  LFS within DPH provides  
               licensing, registration, and certification services to various  
               facilities including clinical laboratories, and the personnel  
               who perform professional pre-analytical, analytical, and  
               post-analytical testing services for these facilities.   





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               Additionally, there are certain requirements, including  
               education, training and examination for specified clinical  
               laboratory personnel, including a clinical laboratory  
               scientist, clinical histocompatibility scientist or clinical  
               laboratory directors.

             Federal CLIA requirements establish standards for laboratories to  
               ensure the accuracy, reliability, and timeliness of patient  
               test results, and specify numerous quality standards, including  
               those for facility administration, personnel qualifications,  
               quality control, and proficiency testing, a process used by  
               laboratories to verify the accuracy and reliability of their  
               test results.  CLIA standards apply to laboratory testing in  
               all states, and in all settings, including commercial,  
               hospital, or physician office laboratories.  CLIA standards are  
               based on the complexity of the testing (waived, moderate, or  
               high complexity).  To become certified under CLIA, a clinical  
               laboratory must pay applicable fees, meet all applicable  
               standards, and be surveyed biennially.  In California, DPH is  
               contracted by CMS to conduct the biennial CLIA survey on behalf  
               of the federal government.  CLIA fees are based on the type of  
               certification sought by a laboratory, and the annual volume and  
               types of testing performed.  

             c)     State Auditor's Report.  In 2008, the Bureau of State  
               Audits (BSA) published a report concluding that LFS had not  
               provided the clinical laboratory oversight mandated by state  
               law and regulations.  Major findings of the BSA revealed that  
               LFS was not inspecting laboratories every two years, as  
               required, inconsistently monitored laboratory proficiency  
               testing, closed many complaints without taking action,  
               sporadically imposed sanctions against laboratories for  
               violations, and, in three instances since fiscal year 2003-04,  
               incorrectly adjusted licensing fees resulting in more than  
               $1,000,000 in lost revenue.  In light of these findings, the  
               Auditor proposed a number of recommendations to leverage  
               existing resources to improve oversight of clinical  
               laboratories, including a recommendation for DPH to approve  
               accrediting organizations to conduct clinical laboratory  
               inspections.  The Auditor stated in the report that DPH had not  
               approved any accreditation organizations to perform such  
               activities, and reported that LFS had expressed concern over  
               the quality of the inspections conducted by accrediting  
               organizations.  The Auditor pointed out that LFS would need to  
               approve accrediting organizations and monitor their compliance,  
               so LFS would have the tools to address these concerns.  





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             In response to the audit report, DPH generally concurred with the  
               Auditor's findings, and attributed much of its inability to  
               meet its mandated responsibilities to a lack of staffing  
               resources.  DPH stated that LFS would take steps to determine  
               how to maximize the use of existing resources, as well as  
               assess how many additional resources would be needed.  DPH  
               stated that licensing revenues would likely be increased to  
               cover costs associated with state oversight mandates.  DPH also  
               stated that it would explore the use of accrediting  
               organization inspectors to conduct inspections for compliance  
               with state law, and that it would work with the appropriate  
               parties to ensure that clinical laboratory licensing fees are  
               properly adjusted in accordance with the Budget Act.  

             To address the funding shortage, which DPH argued resulted in its  
               inability to conduct inspections, investigate complaints,  
               promptly process licensure applications, and take enforcement  
               action when needed, DPH sponsored  SB 744  (Strickland), Chapter  
               201, Statutes of 2009, to among other things, modify the  
               clinical laboratory licensing fee structure, and facilitate the  
               use of private accrediting organizations to inspect clinical  
               laboratories.  At that time, DPH argued that by adjusting and  
               imposing new fees for facility and personnel licensure and  
               certification, charging for re-inspections of laboratories,  
               fining for delinquent laboratory license renewals, and charging  
               fees for licensure of multiple laboratory locations, would  
               provide additional resources for the laboratory oversight  
               program and address many of the problems raised by the BSA  
               audit.

        3. Prior Legislation.   SB 744  (Strickland, Chapter 201, Statutes of  
           2009) revises licensing and certification requirements for clinical  
           laboratories by recognizing accreditation of clinical laboratories  
           by private, nonprofit organizations, as specified, revises license  
           fees according to the number of tests performed, and makes other  
           administrative changes.

        4. Arguments in Support.   Cedars Sinai Health System  indicates that  
           this legislation is designed to overcome some of the roadblocks and  
           oversights in existing regulation and allow many qualified  
           individuals to obtain appropriate clinical laboratory licenses in  
           California. 

        5. Author's Technical Amendments.  The Author would like to amend this  
           bill, as follows:  On page 12, line 8, delete "accrediting" and  





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           "CLIA" and insert after recognized by "the federal HHS"

        (2) The applicant has board certification from an appropriate  
             accrediting  body recognized by   CLIA  the federal HHS  in the area of  
           specialty or subspecialty for which he or she is seeking licensure.

         6. Policy Issue  .  In light of the findings and recommendations of the  
           BSA audit, and the recent passage of  SB 744  which was aimed at  
           improving DPH's responsibilities regarding inspecting laboratories,  
           monitoring testing results, and reviewing and investigating  
           complaints, will creating new laboratory licensure categories and  
           establishing strict timelines for the processing and approval of  
           laboratory personnel slow down DPH's efforts to improve oversight  
           of clinical laboratories?   

        
        SUPPORT AND OPPOSITION:
        
        Support:  

        City of Hope (sponsor)
        California Healthcare Institute
        Cedars Sinai Health System

         Opposition:  

        None on file as of June 21, 2010



        Consultant:Rosielyn Pulmano