BILL ANALYSIS                                                                                                                                                                                                    



                                                                  AB 2145
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          Date of Hearing:  April 13, 2010

                           ASSEMBLY COMMITTEE ON JUDICIARY
                                  Mike Feuer, Chair
                AB 2145 (Ammiano) - As Introduced:  February 18, 2010
           
          SUBJECT  :  DRUG OVERDOSE TREATMENT: LIABILITY

           KEY ISSUES  :  

          1)SHOULD THE EXISTING PILOT PROGRAM FOR OPIOID ANTAGONIST  
            TREATMENT OF DRUG OVERDOSE, WHICH AUTHORIZES LICENSED HEALTH  
            CARE PROVIDERS, WORKING IN CONJUNCTION WITH AN OVERDOSE  
            PREVENTION AND TREATMENT TRAINING PROGRAM, TO PRESCRIBE AND  
            SUBSEQUENTLY DISPENSE OR DISTRIBUTE AN OPIOID ANTAGONIST  
            WITHOUT CIVIL OR CRIMINAL LIABILITY, BE EXPANDED STATEWIDE AND  
            NO LONGER BE SUBJECT TO A SUNSET DATE?

          2)SHOULD LIMITED IMMUNITY FROM CIVIL AND CRIMINAL PENALTIES BE  
            EXTENDED TO LAY PERSONS WHO ADMINISTER AN OPIOID ANTAGONIST IN  
            AN EMERGENCY TO PREVENT THE POSSIBLE DRUG OVERDOSE OF ANOTHER  
            PERSON, AS LONG AS THE LAY PERSON HAS RECEIVED SPECIFIED  
            TRAINING THROUGH A TRAINING PROGRAM APPROVED BY THE LOCAL  
            HEALTH JURISDICTION?

           FISCAL EFFECT  :  As currently in print this bill is keyed fiscal.

                                      SYNOPSIS
          
          SB 767 (Ridley-Thomas) of 2007 established an overdose  
          prevention pilot project that granted limited immunity from  
          civil and criminal penalties to licensed health care providers  
          who, by the same act, were authorized to prescribe and  
          distribute opioid antagonists for emergency treatment of drug  
          overdose.  Seven counties were authorized by SB 767 to develop a  
          so-called "naloxone prescription program" (NPP) and register it  
          with the state, but to this date only San Francisco and Los  
          Angeles Counties have done so.  In order to increase prevention  
          of overdose deaths in the state, this bill seeks to broadly  
          expand parameters of the current pilot project.  First, the bill  
          would expand limited immunity from civil and criminal liability  
          to lay persons who administer an opioid antagonist in an  
          emergency, if that lay person has received appropriate training  
          through a program operated or registered by the local health  
          jurisdiction.  In practice, these persons are most likely to be  








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          friends or acquaintances of the person using opioid drugs,  
          present when an overdose begins and thus in the best position to  
          intervene and administer the opioid antagonist at a point when  
          it will have its greatest lifesaving effect.  This bill would  
          also expand these provisions statewide, while simultaneously  
          deleting the 2011 sunset date, thereby extending these  
          provisions indefinitely.  Supporters generally contend that  
          naloxone prescription programs save lives, and that available  
          data demonstrate that these programs are actively being used to  
          produce safe and effective health outcomes.  Supporters also  
          contend that because naloxone cannot be self-administered by the  
          person experiencing the overdose, it is recommendable to extend  
          protection from liability to third parties who are trained to  
          administer naloxone, or else they will simply avoid employing  
          naloxone in an emergency even when it is available.  This bill  
          is co-sponsored by Harm Reduction California and the Los Angeles  
          Overdose Prevention Task Force, and has no known opposition.

           SUMMARY  :  Seeks to expand parameters of the current pilot  
          program authorizing opioid antagonist (Naloxone) treatment of  
          drug overdose with limited immunity from liability.   
          Specifically,  this bill  :   

          1)Provides that a person who is not otherwise licensed to  
            administer an opioid antidote may administer an opioid  
            antidote in an emergency without fee, if the person believes  
            in good faith that the other person is experiencing a drug  
            overdose, and has received specified training through a  
            training program operated or registered by the local health  
            jurisdiction.  Further provides that the person shall not, as  
            a result of his or her acts or omissions, be liable for any  
            violation of any professional licensing statute, or subject to  
            any criminal prosecution related to the unauthorized practice  
            of medicine or possession of an opioid antidote.

          2)Deletes the provision that currently restricts application of  
            the Naloxone treatment pilot program to only seven authorized  
            counties, thereby expanding application of these provisions  
            statewide.

          3)Deletes the sunset date provision that would repeal authority  
            for the Naloxone treatment pilot program on January 1, 2011,  
            thereby extending these provisions indefinitely.

          4)Deletes the requirement that each local health jurisdiction  








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            that operates or registers an opioid overdose prevention and  
            treatment training program must report specified data by  
            January 1, 2010 to the Senate and Assembly Judiciary  
            Committees.

          5)Requires the Director of Alcohol and Drug Programs to publish  
            an annual report on drug overdose trends statewide that: (a)  
            reviews state death rates to ascertain changes in the causes  
            or rates of fatal and nonfatal drug overdoses for the  
            preceding period of not less than five years; and (b) provides  
            information on interventions that would be effective in  
            reducing the rate of fatal or nonfatal drug overdose.

           EXISTING LAW  :  

          1)Provides that a licensed health care provider who is permitted  
            by law to prescribe an opioid antagonist may, if acting with  
            reasonable care, prescribe and subsequently dispense or  
            distribute an opioid antagonist in conjunction with an opioid  
            overdose prevention and treatment training program, without  
            being subject to civil liability or criminal prosecution. This  
            immunity shall apply to the licensed health care provider even  
            when the opioid antagonist is administered by and to someone  
            other than the person to whom it is prescribed.  (Civil Code  
            Section 1714.22(b).)

          2)Provides that application of these provisions is limited only  
            to the Counties of Alameda, Fresno, Humboldt, Los Angeles,  
            Mendocino, San Francisco, and Santa Cruz.  (Civil Code Section  
            1714.22(d).)

          3)Provides that the pilot authority for Naloxone treatment with  
            limited immunity from liability shall remain in effect only  
            until January 1, 2011, and as of that date is repealed, unless  
            a later enacted statute, that is enacted on or before January  
            1, 2011, deletes or extends that date.  (Civil Code Section  
            1714.22(e).)

          4)Requires each local health jurisdiction that operates or  
            registers an opioid overdose prevention and treatment training  
            program, by January 1, 2010, to collect, and report specified  
            data to the Senate and Assembly Committees on Judiciary on  
            such programs within the jurisdiction.  (Civil Code Section  
            1714.22(c).)









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          5)Defines "opioid antagonist" to mean naloxone hydrochloride  
            that is approved by the federal Food and Drug Administration  
            for the treatment of a drug overdose.  (Civil Code Section  
            1714.22(a)(1).)

          6)Defines "opioid overdose prevention and treatment training  
            program" or "program" to mean any program operated by a local  
            health jurisdiction or that is registered by a local health  
            jurisdiction to train individuals to prevent, recognize, and  
            respond to an opiate overdose, and that provides, at a  
            minimum, training in all of the following:  (a) The causes of  
            an opiate overdose; (b) Mouth to mouth resuscitation; (c) How  
            to contact appropriate emergency medical services; and (d) How  
            to administer an opioid antagonist.  (Civil Code Section  
            1714.22(a)(2).)

          7)Provides a qualified immunity from civil claims for persons  
            rendering cardiopulmonary resuscitation (CPR), in good faith,  
            after completing a basic CPR course, as specified.  (Civil  
            Code Section 1714.2.)

          8)Provides a qualified immunity from civil claims for persons  
            rendering emergency care or treatment by the use of an  
            automatic external defibrillator in good faith.  (Civil Code  
            Section 1714.21.)

          9)Pursuant to federal law, the Controlled Substances Act,  
            regulates the manufacture, importation, possession and  
            distribution of certain controlled substances.  Those  
            substances are classified within five schedules, which are  
            based upon the potential for abuse, addiction, and medical use  
            within the United States.  (21 U.S.C. 801 et seq.)

          10)Pursuant to the California Uniform Controlled Substances Act,  
            strictly regulates the distribution of controlled substances  
            within California (Health & Safety Code  11000 et seq.) and  
            prohibits the prescription, administration, or dispensing of a  
            controlled substance to an addict, except under certain  
            circumstances.  (Health & Safety Code Section 11156; Bus. &  
            Prof. Code Section 2241.)

           COMMENTS  :  This bill, co-sponsored by Harm Reduction California  
          and the Los Angeles Overdose Prevention Task Force, seeks to  
          expand parameters of the current pilot project that grants  
          limited immunity from civil and criminal penalties to licensed  








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          health care providers in seven counties who are authorized to  
          prescribe and distribute opioid antagonists for emergency  
          treatment of drug overdose.  First, the bill would expand  
          limited immunity from civil and criminal liability to lay  
          persons who administer an opioid antagonist in an emergency, if  
          that lay person has received appropriate training through a  
          program operated or registered by the local health jurisdiction.  
           In practice, these persons are most likely to be friends or  
          acquaintances of the person using opioid drugs, present when an  
          overdose begins and thus in the best position to intervene and  
          administer the opioid antagonist at a point when it will have  
          its greatest lifesaving effect.  This bill would also expand the  
          pilot provisions statewide, while simultaneously deleting the  
          2011 sunset date, thereby extending these provisions  
          indefinitely.
           
          Background on properties of naloxone, a common opioid  
          antagonist  :  Opioid antagonists are a group of drugs routinely  
          used in hospitals and in pre-hospital settings (i.e. by  
          paramedics in the field) on patients who are suspected to be  
          overdosing on opioids such as heroin, methadone, or oxycodone.   
          The most common type of opioid antagonist is known as naloxone  
          (or its brand name "Narcan"), and hereafter this analysis will  
          use the term "naloxone" interchangeably with the term "opioid  
          antagonist."

          Opioid overdoses are characterized by central nervous system and  
          respiratory depression, leading to coma and death.  Naloxone,  
          like other opioid antagonists, has the ability to counteract  
          depression of the central nervous and respiratory system caused  
          by an opioid overdose.  Naloxone is administered by injection  
          into vein or muscle, with intravenous injection providing for  
          the fastest action.  Once injected, naloxone takes effect after  
          around two minutes, with effects lasting around 45 minutes,  
          potentially saving the person's life.  A New York Times article  
          published August 21, 2005 ("The Shot That Saves ") noted:

            If given early enough, naloxone can prevent damage to the  
            brain caused by lack of oxygen and leave the victim  
            unharmed. According to research   . . .  at least 75  
            percent of overdose deaths involve multiple drugs, usually  
            mixtures of heroin and other depressants like alcohol.  
            Removing the opioid from the mix with naloxone is often  
            enough to revive victims.  









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            Naloxone itself is virtually harmless. Its most common  
            side effects are withdrawal symptoms like nausea,  
            shakiness and agitation in those who are physically  
            dependent on opioids. While uncomfortable, these symptoms  
            are not dangerous. Rarely, seizures can occur, but this  
            risk is far lower than the risk to those who are not  
            treated. The drug has no effect on those who haven't taken  
            opioids. 

           Implementation of Overdose Prevention Programs in California.    
          According to the Harm Reduction Coalition, overdose prevention  
          programs that dispense naloxone (often referred to as "naloxone  
          prescription programs", or NPPs) have been operating legally in  
          California for ten years, with different levels of support from  
          city and county public health departments and community-based  
          organizations.  There currently are 18 naloxone prescription  
          programs operating in twelve counties in CA.  Of these twelve  
          counties, only seven (San Francisco, Los Angeles, Alameda,  
          Fresno, Humboldt, Mendocino, and Santa Cruz) are authorized to  
          participate in the specific pilot project created by SB 767  
          (2007), which this bill seeks to expand.  Only San Francisco and  
          Los Angeles, however, have actually registered their overdose  
          prevention programs with the state and have reported data to the  
          Legislature pursuant to SB 767. 

          According to supporters, these programs do more than just  
          dispense naloxone.  Supporters state that NPPs "provide lay  
          community members (including drug users, their friends, and  
          family members) with the training and tools necessary to  
          intervene effectively when they witness a drug overdose.  These  
          programs also provide overdose prevention, recognition, and  
          response training, including training in calling 911, rescue  
          breathing and utilization of take-home prescriptions of  
          naloxone."  

           Supporters contend NPPs are safe and effective, justifying  
          removal of the sunset date for the SB 767 pilot program.    
          Proponents of this bill contend, very simply, that naloxone  
          prescription programs save lives, and that available data from  
          San Francisco and Los Angeles pilot programs demonstrate that  
          these programs are actively being used to produce safe and  
          effective health outcomes.  These supporters cite numerous  
          research findings, including the following:

                 In San Francisco, between January 2008 and December  








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               2009, 749 individuals were trained and prescribed  
               naloxone.  Of these, 156 (21%) returned for refills  
               because they reported using naloxone to revive an  
               overdose victim.  These project participants reported a  
               total of 153 successful overdose reversals-meaning that  
               in only three cases (or only 2% of the time) a person  
               experiencing drug overdose received naloxone but was not  
               revived.
                 In Los Angeles, during an equivalent period, 273  
               individuals were trained and prescribed naloxone.  These  
               273 individuals reported responding to a total of 82  
               overdoses, of which at least 71 (93%) of the overdose  
               victims were known to have survived.
                 Additional San Francisco data, reflecting  
               implementation of their naloxone program predating SB  
               767, indicate a decline in heroin-related overdose deaths  
               from over 120 per year in 2000, to under 60 per year in  
               2005.  In addition, since 2003, over 2,000 prescriptions  
               of naloxone were distributed in total, resulting in a  
               reported 455 lives saved by laypersons trained through  
               the San Francisco program  (A.P. Hart, City & County of  
               San Francisco, Annual Report (2006).)
           
           Supporters of this bill also relate that, outside of California,  
          there are over 100 naloxone prescription programs operating in  
          17 U.S. states, and they have been shown to be highly effective.  
           (A complete report summarizing these findings is available on  
          the Internet at:
           http://papers.ssrn.com/sol3/papers.cfm?abstract_id=1437163  ).

          In general, the supporters of this bill enthusiastically  
          describe the potential lifesaving effects of making opioid  
          antagonists available to various individuals who may be in the  
          presence of an opioid overdose.  Those accounts are based upon  
          existing distribution programs, which have reported few if any  
          complications and undoubtedly saved numerous lives.  The  
          Committee has not been made aware of any suits or prosecutions  
          as a result of the current distribution of opioid antagonists.

           Supporters contend that high rates of preventable drug overdose  
          in many counties justify statewide expansion of the pilot  
          program.   Proponents of this bill contend that accidental drug  
          overdose is a prevalent problem across the state, and that  
          expansion of the pilot program would help to address unmet needs  
          in many counties that currently do not enjoy the protections  








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          provided by the SB 767 pilot project.  According to the most  
          recent report by California Alcohol and Drug Programs, the  
          counties with the highest number of overdose deaths in 2006 were  
          Kern, Orange, Riverside, Sacramento, San Bernardino, San Diego,  
          Santa Clara, Alameda, Fresno, San Francisco, and Los Angeles.   
          The author notes that only the latter four counties are  
          authorized as sites for pilot programs in SB 767, and asserts  
          that there are a number of counties that already have NPPs that  
          merit protection, as well as many high-need counties yet to  
          implement programs that would stand to benefit from statewide  
          expansion proposed by this bill.

           Reasons for liability protection for third parties who  
          administer naloxone.   Supporters contend that because naloxone  
          cannot be self-administered by the person experiencing the  
          overdose, it is recommendable to extend protection from  
          liability to third parties who are trained to administer  
          naloxone, or else they will simply avoid employing naloxone in  
          an emergency even when it is available.  The author explains:

               Opioid overdose is characterized by unconsciousness  
               caused by failure of the respiratory system.  
               Therefore, if the person prescribed naloxone is the  
               one who is at-risk, he will not be able to use it on  
               himself when actually needed.  A companion trained in  
               naloxone administration must be present to administer  
               the life-saving drug. Friends, family members, workers  
               in homeless shelters, residential hotels, and drug  
               treatment programs are often first responders in an  
               overdose crisis, but may be fearful to carry a  
               naloxone prescription because of the lack of 3rd party  
               protection. A trained, informed Good Samaritan  
               deserves to keep naloxone in the first aid kit or  
               medicine cabinet without needless concern.
           
          Supporters report that county health workers who operate or who  
          desire to operate a NPP report having difficulty finding health  
          care providers who are comfortable writing prescriptions for a  
          medication that will, by necessity, be administered by a third  
          party, without reasonable liability protection.  Furthermore,  
          supporters assert that even so-called "frontline workers" who  
          have taken overdose prevention trainings, and who often are in  
          close contact with drug users at sites like homeless shelters  
          and drug treatment facilities, nevertheless are reluctant to  
          keep the naloxone close at hand for emergency response, without  








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          any legal protection for a third party who administrates  
          naloxone.

           REGISTERED SUPPORT / OPPOSITION  :   

           Support 
           
          Harm Reduction Coalition (sponsor)
          California Public Defenders Association
          City and County of San Francisco
          Coalition on Homelessness, San Francisco
          County Alcohol and Drug Program Administrators Association of  
          California (CADPAAC)
          Desert AIDS Project
          Drug Policy Alliance
          San Francisco AIDS Foundation

           Opposition 
           
          None on file
           
          Analysis Prepared by  :   Anthony Lew / JUD. / (916) 319-2334