BILL ANALYSIS                                                                                                                                                                                                    



                                                                  SB 249
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          Date of Hearing:   June 30, 2009

                            ASSEMBLY COMMITTEE ON HEALTH
                                  Dave Jones, Chair
                      SB 249 (Cox) - As Amended:  April 27, 2009

           SENATE VOTE  :   36-0
           
          SUBJECT  :   Vaccinations: meningitis.

           SUMMARY  :   Requires the Department of Public Health (DPH) to  
          include, no later than April 1, 2010, as part of information  
          about meningococcal disease DPH is already required to develop,  
          information pertaining to children between 11 and 18 years of  
          age.  

           EXISTING LAW  :

          1)Requires DPH to develop information about meningococcal  
            disease, including symptoms, risk, treatment, and vaccination,  
            and to make that information available to each public and  
            private degree-granting postsecondary institution and upon  
            request.

          2)Requires DPH to send each school district an information  
            notice advising of the availability of the meningococcal  
            information and provide it upon request.

          3)Authorizes DPH to use the information developed in 1) above to  
            design and implement a public awareness campaign about  
            meningococcal disease to reach members of the population  
            identified as being at high risk for contracting the disease.

           FISCAL EFFECT  :   According to the Senate Appropriations  
          Committee, pursuant to Senate Rule 28.8, negligible state costs.

           COMMENTS  .

           1)PURPOSE OF THIS BILL  .  According to the author, in August  
            2007, the United States (U.S.) Centers for Disease Control and  
            Prevention (CDC) and Advisory Committee on Immunization  
            Practices (ACIP) issued a recommendation to vaccinate children  
            ages 11 to18 years at the earliest opportunity to prevent  
            invasive meningococcal disease.  The author states this  
            recommendation is supported by the American Academy of  








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            Pediatrics, the American Academy of Family Physicians, and  
            others.  The author contends this bill would help ensure that  
            parents, health care providers and others are educated about  
            the disease, the recent ACIP recommendations, and the  
            availability of a vaccine to prevent meningococcal disease in  
            11 to 18 year olds. 

           2)MENINGOCOCCAL DISEASE  .  According to CDC, meningococcal  
            disease is caused by Neisseria meningitidis, or the  
            meningococcus, and is a potentially severe bacterial infection  
            that can cause meningitis, bloodstream infection, and  
            localized infections.  Although meningococcal disease is not  
            common in the U.S., the disease is of concern because it can  
            progress rapidly and lead to death within hours of onset.   
            Meningococcal disease takes several forms, including  
            meningitis, which is characterized by fever, headache, and  
            stiff neck, and in some cases, nausea, vomiting, and changes  
            in mental status.  Another form of meningococcal disease,  
            meningococcal bacteremia, is a bloodstream infection  
            characterized by sudden fever and, in severe cases, small red  
            or purple spots or red or purple discolorations on the skin.   
            Meningococcal bacteremia can lead to joint infection,  
            pneumonia, organ system failure, shock, and death.  According  
            to DPH, approximately 10% of persons with meningococcal  
            disease die from the infection, and 11%-19% of those who  
            survive suffer long-term complications, such as limb loss,  
            neurologic disability, or hearing loss.

          Meningococcal disease is spread by respiratory droplets or  
            secretions (from coughing, sneezing, and kissing) of people  
            with the disease or healthy carriers of the meningococcus who  
            have no symptoms.  Infants are at greatest risk of  
            meningococcal disease, although DPH reports that the incidence  
            among adolescents and young adults has been increasing.
          Close household contacts to infected persons are at greatly  
            increased risk of infection.  Smoking and second-hand smoke,  
            upper respiratory viral infections, and crowded living  
            conditions also appear to increase risk of infection. 

           3)MENINGOCOCCAL VACCINES  .  According to CDC, two meningococcal  
            vaccines are available in the U.S.  These vaccines cannot  
            prevent all types of meningococcal disease but can prevent two  
            of the three types most common in the U.S. and a type that  
            causes epidemics in Africa.  The federal Food and Drug  
            Administration approved meningococcal polysaccharide vaccine  








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            (MPSV4) in 1981.  In January 2005, the meningococcal conjugate  
            vaccine (MCV4) was licensed for use among persons 11 to 55  
            years of age.  According to CDC, MCV4 is the preferred vaccine  
            for people two to 55 years of age, but MPSV4 can be used if  
            MCV4 is not available.  MPSV4 is the only meningococcal  
            vaccine approved for persons older than 55 years. 

          Shortly after the approval of MCV4 in 2005, ACIP recommended  
            routine vaccination with one dose of MCV4 for 11 to 12 year  
            olds, persons entering high school if not previously  
            vaccinated, college freshmen in dormitories, and others at  
            increased risk.  In June 2007, based on MCV4 use and supply  
            projections as well as data on the epidemiology of  
            meningococcal disease, safety, and cost-effectiveness, ACIP  
            extended its recommendation to include routine vaccination of  
            all persons 11 to  18  years of age at the earliest opportunity.  
             Thus, the current ACIP and CDC recommendation is for all  
            children to receive MCV4 at their routine preadolescent  
            medical visit (11 to 12 years of age) or at the earliest  
            opportunity for 11 to 18 year olds, and, for those who have  
            never gotten MCV4, at high school entry.  CDC and ACIP further  
            recommend routine vaccination for people at increased risk,  
            including college freshmen living in dormitories,  
            microbiologists who are routinely exposed to meningococcal  
            bacteria, U.S. military recruits, people with specified  
            medical conditions, anyone who is traveling to countries with  
            a meningococcal disease outbreak, and those who might have  
            been exposed to meningitis during an outbreak.

           4)MENINGOCOCCAL DISEASE AND PREVENTION IN CALIFORNIA  .  According  
            to DPH, between 1995 and 2000, the number of cases of  
            meningococcal disease ranged from 306 to 436 annually.  In  
            2000-01, outbreaks of meningococcal disease in young adults in  
            five California public schools focused attention on this  
            disease.  In response to the outbreaks, SB 212 (Oller),  
            Chapter 374, Statutes of 2001, requires DPH to develop a  
            meningococcal disease strategic prevention plan.  DPH convened  
            a working group and published the Meningococcal Disease  
            Prevention Plan in September 2002.  The working group adopted  
            recommendations for vaccine use and information, education,  
            and training, including recommendations to follow ACIP  
            guidelines and that DPH make information on meningococcal  
            disease and prevention available to college-bound and other  
            high school seniors.  Accordingly, DPH developed materials  
            about meningococcal disease and vaccine for students,  








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            including the "Vaccinate Before you Graduate" campaign aimed  
            at high school students.  DPH also developed a brochure aimed  
            at freshmen in dorms, and sent letters to colleges to inform  
            them of the availability of the brochure for download and  
            inclusion in registration materials.  DPH also posts all  
            meningococcal disease materials on its Web site and  
            distributes the materials to local health departments.  After  
            the introduction of MCV4, DPH made the vaccine available to  
            all eligible children in publicly funded health programs  
            through the Vaccines for Children Program, and states the  
            vaccine was quickly adopted.  

           5)RELATED AND PREVIOUS LEGISLATION  .  

             a)   SB 212 (Florez), pending in the Assembly, authorizes  
               each school district with a high school to provide for the  
               annual cleaning and sterilizing of wrestling equipment, and  
               requires the Superintendent of Public Instruction to  
               develop information and guidelines regarding the prevention  
               of communicable diseases, including meningococcal disease,  
               at school sites.

             b)   AB 1452 (Cox), Chapter 372, Statutes of 2001, requires  
               DPH to develop information regarding meningococcal disease  
               and make the information available to requesting school  
               districts and degree-granting postsecondary educational  
               institutions.

             c)   SB 212 (Oller), Chapter 374, Statutes of 2001, requires  
               DPH to develop a Meningococcal Disease Strategic Prevention  
               Plan.

           6)SUPPORT  .  Sanofi-Pasteur, the sponsor of this bill, writes in  
            support that meningococcal disease fatality rates are up to  
            five times higher among 15 to 24 year olds and that this bill  
            simply adds children who are at least 11 years old to current  
            law, pursuant to the 2007 recommendation of ACIP and CDC.  The  
            California School Nurses Organization states in support of  
            this bill that it is vital that parents receive information  
            regarding this disease and the vaccine so they can decide  
            whether to vaccinate their children.  The California State PTA  
            also contends this bill educates parents and will enable  
            parents to make informed decisions regarding their children's  
            health.  The National Meningitis Association argues in support  
            of this bill that no parent should lose a child to a  








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            potentially vaccine-preventable disease.  

           REGISTERED SUPPORT / OPPOSITION  :

           Support  
          Sanofi-Pasteur (sponsor)
          California School Nurses Organization
          California State PTA
          National Meningitis Association

           Opposition
           
          None on file. 

           Analysis Prepared by  :    Allegra Kim / HEALTH / (916) 319-2097