BILL ANALYSIS                                                                                                                                                                                                    



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          SENATE THIRD READING
          SB 249 (Cox)
          As Amended  April 27, 2009
          Majority vote 

           SENATE VOTE  :36-0  
           
           HEALTH              16-0        APPROPRIATIONS      15-0        
           
           ----------------------------------------------------------------- 
          |Ayes:|Jones, Fletcher, Adams,   |Ayes:|De Leon, Nielsen,         |
          |     |Block, Carter,            |     |Ammiano,                  |
          |     |    Conway, De Leon,      |     |Charles Calderon, Coto,   |
          |     |Emmerson, Gaines, Hall,   |     |Davis, Duvall, Fuentes,   |
          |     |Hayashi, Hernandez,       |     |Hall, Harkey, Miller,     |
          |     |Bonnie Lowenthal, Nava,   |     |John A. Perez, Skinner,   |
          |     |V. Manuel Perez, Audra    |     |Audra Strickland,         |
          |     |Strickland                |     |Torlakson                 |
          |-----+--------------------------+-----+--------------------------|
          |     |                          |     |                          |
           ----------------------------------------------------------------- 
           SUMMARY  :  Requires the Department of Public Health (DPH) to  
          include, no later than April 1, 2010, as part of information  
          about meningococcal disease DPH is already required to develop,  
          information pertaining to children between 11 and 18 years of  
          age.  

           EXISTING LAW  requires DPH to develop information about  
          meningococcal disease, including symptoms, risk, treatment, and  
          vaccination, and to make that information available to each  
          public and private degree-granting postsecondary institution and  
          upon request.

           FISCAL EFFECT  :  According to the Assembly Appropriations  
          Committee analysis, no direct fiscal impact assuming the  
          information DPH currently has posted on their web site meets the  
          requirement of this bill.  If additional information needs to be  
          developed, a one-time federal funds cost of $20,000-$30,000 will  
          be incurred.

           COMMENTS  :  According to the author, in August 2007, the United  
          States (U.S.) Centers for Disease Control and Prevention (CDC)  
          and Advisory Committee on Immunization Practices (ACIP) issued a  
          recommendation to vaccinate children ages 11 to18 years at the  








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          earliest opportunity to prevent invasive meningococcal disease.   
          The author states this recommendation is supported by the  
          American Academy of Pediatrics, the American Academy of Family  
          Physicians, and others.  The author contends this bill would  
          help ensure that parents, health care providers and others are  
          educated about the disease, the recent ACIP recommendations, and  
          the availability of a vaccine to prevent meningococcal disease  
          in 11 to 18 year olds. 

          According to CDC, meningococcal disease is caused by Neisseria  
          meningitidis, or the meningococcus, and is a potentially severe  
          bacterial infection that can cause meningitis, bloodstream  
          infection, and localized infections.  Although meningococcal  
          disease is not common in the U.S., the disease is of concern  
          because it can progress rapidly and lead to death within hours  
          of onset.  Meningococcal disease takes several forms, including  
          meningitis, which is characterized by fever, headache, and stiff  
          neck, and in some cases, nausea, vomiting, and changes in mental  
          status.  Another form of meningococcal disease, meningococcal  
          bacteremia, is a bloodstream infection characterized by sudden  
          fever and, in severe cases, small red or purple spots or red or  
          purple discolorations on the skin.  Meningococcal bacteremia can  
          lead to joint infection, pneumonia, organ system failure, shock,  
          and death.  According to DPH, approximately 10% of persons with  
          meningococcal disease die from the infection, and 11%-19% of  
          those who survive suffer long-term complications, such as limb  
          loss, neurologic disability, or hearing loss.

          Meningococcal disease is spread by respiratory droplets or  
          secretions (from coughing, sneezing, and kissing) of people with  
          the disease or healthy carriers of the meningococcus who have no  
          symptoms.  Infants are at greatest risk of meningococcal  
          disease, although DPH reports that the incidence among  
          adolescents and young adults has been increasing.  Close  
          household contacts are at greatly increased risk of infection.   
          Smoking and second-hand smoke, upper respiratory viral  
          infections, and crowded living conditions also appear to  
          increase risk of infection. 

          According to CDC, two meningococcal vaccines are available in  
          the U.S.  These vaccines prevent two of the three meningococcal  
          disease types most common in the U.S. and a type that causes  
          epidemics in Africa.  The federal Food and Drug Administration  
          approved meningococcal polysaccharide vaccine (MPSV4) in 1981.   








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          In January 2005, the meningococcal conjugate vaccine (MCV4) was  
          licensed for use among persons 11 to 55 years of age.  According  
          to CDC, MCV4 is the preferred vaccine for people two to 55 years  
          of age, but MPSV4 can be used if MCV4 is not available.  MPSV4  
          is the only meningococcal vaccine approved for persons older  
          than 55 years. 

          Shortly after the approval of MCV4 in 2005, ACIP recommended  
          routine vaccination with one dose of MCV4 for 11 to 12 year  
          olds, persons entering high school if not previously vaccinated,  
          college freshmen in dormitories, and others at increased risk.   
          In June 2007, ACIP extended its recommendation to include  
          routine vaccination of all persons 11 to 18 years of age at the  
          earliest opportunity.  Thus, the current ACIP and CDC  
          recommendation is for all children to receive MCV4 at their  
          routine preadolescent medical visit (11 to 12 years of age) or  
          at the earliest opportunity for 11 to 18 year olds, and, for  
          those who have never gotten MCV4, at high school entry.  CDC and  
          ACIP further recommend routine vaccination for people at  
          increased risk, including college freshmen living in dormitories  
          and others. 

          In 2000-01, outbreaks of meningococcal disease in young adults  
          in five California public schools focused attention on this  
          disease.  In response to the outbreaks, SB 212 (Oller), Chapter  
          374, Statutes of 2001, requires DPH to develop a meningococcal  
          disease strategic prevention plan.  DPH convened a working group  
          and published the Meningococcal Disease Prevention Plan in  
          September 2002.  The working group adopted recommendations for  
          vaccine use and information, education, and training, including  
          recommendations to follow ACIP guidelines and that DPH make  
          information on meningococcal disease and prevention available to  
          college-bound and other high school seniors.  Accordingly, DPH  
          developed materials about meningococcal disease and vaccine for  
          students, including the "Vaccinate Before you Graduate" campaign  
          aimed at high school students.  DPH also developed a brochure  
          aimed at freshmen in dorms, and sent letters to colleges to  
          inform them of the availability of the brochure for download and  
          inclusion in registration materials.  DPH also posts all  
          meningococcal disease materials on its Web site and distributes  
          the materials to local health departments.  


           Analysis Prepared by  :    Allegra Kim / HEALTH / (916) 319-2097 








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