BILL ANALYSIS                                                                                                                                                                                                    



                                                                  SB 1064
                                                                  Page  1

          Date of Hearing:   August 4, 2010

                        ASSEMBLY COMMITTEE ON APPROPRIATIONS
                                Felipe Fuentes, Chair

                   SB 1064 (Alquist) - As Amended:  June 17, 2010 

          Policy Committee:                             Health Vote:19-0

          Urgency:     No                   State Mandated Local Program:  
          No     Reimbursable:              

           SUMMARY  

          This bill increases oversight and transparency requirements for  
          the California Institute for Regenerative Medicine (CIRM), which  
          was established by Proposition 71 in 2004 to provide support for  
          stem cell research in California. Specifically, this bill: 

          1)Requires CIRM to commission a performance audit every three  
            years and requires CIRM to pay for the triennial audits.

          2)Requires all revenues received through intellectual property  
            agreements to be deposited in the state General Fund.

          3)Requires CIRM's intellectual property standards to include a  
            requirement that each grantee or exclusive licensee submit a  
            plan to provide uninsured Californians access to any drug that  
            is entirely or partly the result of CIRM-funded research.

          4)Contains several staffing, management, and grants  
            administration provisions. This bill eliminates a 50-person  
            staffing cap currently imposed on CIRM. 

           FISCAL EFFECT  

          1)Audit costs of $200,000 to $400,000 every three years. This  
            bill requires CIRM to pay these costs from the California Stem  
            Cell and Research Cures Fund, the bond funding that supports  
            CIRM. 

          2)Unknown bond-fund supported increases in salaries and overhead  
            to the extent CIRM increases staffing above current levels.  
            Increased staffing costs may range from $500,000 to several  
            million dollars depending on how close CIRM is currently to  








                                                                  SB 1064
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            expenditure caps. 

          3)Unknown future GF revenues to the extent the requirement for  
            GF deposits related to intellectual property agreements  
            established by this bill increases state revenues. Because  
            medications, therapies, and technologies take years to  
            successfully develop, a GF benefit may not be seen for 10  
            years or more. 

           COMMENTS  

           1)Rationale  . This bill makes several changes to the  
            administration and functioning of CIRM. Several of the  
            provisions are based on a 2009 Little Hoover report. The  
            report included recommendations to deliberately guide  
            California's investment in stem cell science and improve  
            CIRM's operational efficiencies. 

           2)Proposition 71  was approved by voters in November 2004 to  
            authorize the state to sell $3 billion in general obligation  
            bonds to provide funding for stem cell research in California.  
            The issue was put before the voters to address federal  
            restrictions on the use of human embryonic stem cells. CIRM,  
            which is governed by the Independent Citizen's Oversight  
            Committee (ICOC), is required to award grants and loans and to  
            adopt governance, scientific, medical and regulatory standards  
            in public meetings.  Proposition 71 requires the ICOC to  
            establish standards for IP agreements that balance public  
            benefit with the assurance that medical research and private  
            investment is not hindered by IP agreements.   

           Analysis Prepared by  :    Mary Ader / APPR. / (916) 319-2081