BILL ANALYSIS                                                                                                                                                                                                    �



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          Date of Hearing:   May 3, 2011

                            ASSEMBLY COMMITTEE ON HEALTH
                              William W. Monning, Chair
                 AB 1000 (Perea) - As Introduced:  February 18, 2011
           
          SUBJECT  :  Health care coverage: cancer treatment.

           SUMMARY  :  Requires a health care service plan (health plan) 
          contract or health insurance policy that provides coverage for 
          cancer chemotherapy treatment to establish limits on enrollee 
          out of pocket costs for prescribed, orally administered, 
          nongeneric cancer medication.   Specifically,  this bill  :   

          1)Requires a health plan contract or health insurance policy 
            issued, amended, or renewed on or after January 1, 2011, that 
            provides coverage for cancer chemotherapy treatment, to 
            provide coverage for prescribed, orally administered, 
            nongeneric cancer medication, used to kill or slow the growth 
            of cancerous cells.

          2)Requires the health plan contract or health insurance policy 
            referenced in 1) above, to review the percentage cost share 
            for oral nongeneric cancer medication and intravenous (IV) or 
            injected nongeneric cancer medications and apply the lower of 
            the two as the cost-sharing provision for oral nongeneric 
            cancer medications.

          3)Prohibits a health plan contract or health insurance policy 
            from providing an increase in enrollee cost sharing for 
            nongeneric cancer medications to any greater extent than the 
            contract or policy provides for an increase in enrollee cost 
            sharing for other nongeneric covered medications.

          4)Defines "cost share" as copayment, coinsurance, or deductible 
            provisions applicable to coverage for oral, IV, or injected 
            nongeneric cancer medications.

          5)Prohibits the provisions of this bill from being construed to 
            require a health plan contract or health insurance policy to 
            provide coverage for any additional medication not otherwise 
            required by law.

          6)Clarifies that provisions of this bill do not prohibit a 
            health plan contract or health insurance policy from removing 








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            a prescription drug from its formulary of covered prescription 
            drugs.

          7)Prohibits the provisions of this bill from applying to a 
            health plan contract or health insurance policy that does not 
            provide coverage for prescription drugs.

          8)Prohibits the provision of this bill from applying to a health 
            care benefit plan or contract entered into with the Board of 
            Administration of the Public Employees' Retirement System 
            (CalPERS) pursuant to the Public Employees' Medical and 
            Hospital Care Act.

          9)Requires the provisions of this bill to remain in effect only 
            until January 1, 2016, and as of that date are repealed, 
            unless a later enacted statute deletes or extends that date.


           EXISTING FEDERAL LAW  :

          1)Enacts, in federal law, the Patient Protection and Affordable 
            Care Act (PPACA) to, among other things, make statutory 
            changes affecting the regulation of, and payment for, certain 
            types of private health insurance.  Includes the definition of 
            essential health benefits (EHBs) that all qualified health 
            plans must cover, at a minimum, with some exceptions.

          2)Provides that the EHB package in 1) above will be determined 
            by the federal Department of Health and Human Services (HHS) 
            Secretary and must include, at a minimum, ambulatory patient 
            services; emergency services; hospitalizations; mental health 
            and substance abuse disorder services, including behavioral 
            health; prescription drugs; and, rehabilitative and 
            habilitative services and devices, among other things.

           EXISTING STATE LAW  :

          1)Establishes the Knox-Keene Health Care Service Plan Act of 
            1975 to regulate and license health plans and specialized 
            health plans by the Department of Managed Health Care (DMHC) 
            and provides for the regulation of health insurers by the 
            California Department of Insurance (CDI).

          2)Requires health plan contracts and health insurance policies 
            to provide coverage for all generally medically accepted 








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            cancer screening tests and requires those plans and policies 
            to also provide coverage for the treatment of breast cancer.

          3)Imposes various requirements on health plan contracts and 
            health insurance policies that cover prescription drug 
            benefits, such as a requirement to cover "off-label" uses, as 
            specified, and a requirement to cover previously prescribed 
            drugs, as specified.

          4)Authorizes DMHC to regulate the provision of medically 
            necessary prescription drug benefits by a health plan to the 
            extent that the plan provides coverage for those benefits.  
            Existing regulation requires health plans providing outpatient 
            prescription drugs to provide all medically necessary 
            prescription drugs, except as specified in that regulation.

           FISCAL EFFECT  :   This bill has not yet been analyzed by a fiscal 
          committee.

           COMMENTS  :    

           1)PURPOSE OF THIS BILL  . According to the author, the emergence 
            of safe, clinically effective, orally administered anticancer 
            medication has significantly increased the treatment options 
            for cancer patients; however, many barriers currently impede 
            the adoption of orally administered treatment as the main form 
            of cancer therapy.  The author maintains that one of the most 
            significant barriers is reflected in the disparity between 
            medical and pharmacy benefit designs resulting in greater 
            patient out-of-pocket costs for oral therapies covered under 
            the pharmacy benefit than IV therapies covered under the 
            medical benefit.  The author further maintains that, where IV 
            administered anticancer medications are typically covered 
            under a plan's medical benefit, most patients are only 
            responsible for an office co-payment for each episode of care 
            and are not required to pay a separate fee for the IV drug.  
            The author argues that, in contrast, orally administered 
            anticancer medications are typically covered under a plan's 
            pharmacy benefit, where many of these agents are placed on a 
            4th or specialty tier of a prescription plan's formulary.  The 
            author points out that, according to the Kaiser Family 
            Foundation, the average coinsurance rate for 4th tier drugs is 
            28%, which, for a $3,000 per month oral anticancer medication, 
            could expose a patient to $900 in out-of-pocket spending.  
            Citing a study done by Prime Therapeutics, which concluded 








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            that 1-in-6 patients did not receive oral anticancer treatment 
            solely due to cost, the author maintains that out-of-pocket 
            costs for oral anticancer medications becomes a de facto 
            denial of access.

          The author additionally points out that, in 2007, the Oregon 
            State Senate passed similar legislation �S.B. 8 (Courtney), 
            Chapter 566, 2007 Laws], and that, upon enactment of S.B. 8 in 
            January 2008, the top state plans eliminated their high 
            coinsurance rates.  Most Oregon plans eliminated their high 
            coinsurance rates and established separate oral anticancer 
            therapy coverage under their pharmacy benefit, and patients 
            with no pharmacy benefits gained access to oral anticancer 
            agents through their medical benefit.  The author further 
            notes that, Colorado, Hawaii, Indiana, Iowa, Kansas, 
            Minnesota, Vermont, Washington D.C., and Connecticut have all 
            passed similar legislation.

           2)MEDICAL AND PHARMACY BENEFITS  .  According to the California 
            Health Benefits Review Program's (CHBRP's) analysis of SB 961 
            (Wright) of 2009, identical to this bill, coverage for 
            anticancer medications can differ in any of a number of ways, 
            depending on provisions of a person's health plan contract or 
            health insurance policy with a carrier.  At a very broad 
            level, anticancer medications may be covered as pharmacy plan 
            benefits or as medical plan benefits, and most plans and 
            insurers depend on the dispensing site to determine which will 
            be the form of coverage.  IV anticancer medication, which is 
            usually provided in a hospital or a physician's office, is 
            generally covered as a medical benefit.  Oral anticancer 
            medications (usually pills) dispensed by a pharmacy are 
            usually covered as a pharmacy benefit.  Some injected 
            anticancer medications are considered "self-injectable," and 
            so are regularly delivered through a pharmacy and covered as a 
            pharmacy benefit.  In part, these variations are due to the 
            fact that pharmacy benefits are relatively new for carrier 
            contracts and policies, having been added in the 1970s and 
            1980s, long after hospitalization and physician visits had 
            become covered medical benefits. 

          CHBRP indicates for both medical and pharmacy benefits, payers 
            have devised strategies to promote appropriate utilization and 
            control of costs.  A short list of these strategies includes: 
            creation of formularies; maximization of manufacturer rebates; 
            quantity restrictions; use of prior authorization; development 








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            of clinical guidelines; and, implementation of patient cost 
            sharing, such as deductibles, coinsurance, and copayments.  
            Cost sharing for medications is frequently complicated by 
            tiered pricing.  A health plan and health insurer may assign 
            drugs to tiers (generic drugs in the lowest and very expensive 
            drugs in the highest) and apply varying copayments and 
            coinsurance rates to different tiers.  As with cost sharing in 
            general, the impact of tiers (if any) depends on the specifics 
            of a person's health plan contract or health insurance policy. 


          According to CHBRP, the variety of cost sharing provisions 
            currently used in California makes it difficult to generalize 
            about the ways in which a cancer patient may be required to 
            pay out-of-pocket for any anticancer medication.  Fixed 
            copayments are a common form of cost sharing for medications 
            delivered through a pharmacy.  However, some carrier contracts 
            and polices specify coinsurance for one or more medications.  
            The terms of coverage may or may not include a deductible.  
            The coverage of medications delivered as medical benefits is 
            equally variable.
           3)CHBRP  .  CHBRP was created in response to AB 1996 (Thomson), 
            Chapter 795, Statutes of 2002, which requests the University 
            of California to assess legislation proposing a mandated 
            benefit or service, and prepare a written analysis with 
            relevant data on the public health, medical, and economic 
            impact of proposed health plan and health insurance benefit 
            mandate legislation.  CHBRP's analysis of this legislation 
            focuses on oral anticancer medications, specifically, oral 
            medications used to kill or slow the growth of cancerous 
            cells.  This analysis assumes that this bill does not affect 
            cost sharing for other medications that a cancer patient might 
            use during the course of chemotherapy.  Among CHBRP's findings 
            are the following:

              a)   Overview of Oral Anti-Cancer Medications  .  According to 
               CHBRP, anticancer medications may be administered through 
               an IV, by injection, or orally.  CHBRP maintains that 
               although oral anticancer medications have been available 
               for many years, the number of oral anticancer medications 
               approved by the U.S. Food and Drug Administration (FDA) has 
               grown dramatically over the past decade and that growth is 
               likely to continue.  To date, according to CHBRP, the FDA 
               has approved 42 oral anticancer medications that are used 
               to treat 57 different types of cancer.  CHBRP cites the 








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               National Comprehensive Cancer Network report that estimates 
               400 anticancer medications are currently under development, 
               and approximately 25% of them are planned to be 
               administered orally.  CHBRP notes that for many anticancer 
               medications there are no IV or injected substitutes.  

             Provisions of this bill only apply to cost sharing for 
               nongeneric oral anticancer medications.  CHBRP reports that 
               most oral anticancer medications are available as 
               brand-name only (i.e., nongeneric) medications.  Generic 
               equivalents are available for only 10 of the 42 oral 
               anticancer medications currently approved by the FDA.  
               CHBRP notes that many of the oral anticancer medications 
               are relatively new medications for which the pharmaceutical 
               company that developed the medication has exclusive 
               marketing rights and/or for which the patent has not 
               expired.  Although generic equivalents are available for 
               less than one-quarter of oral anticancer medications, they 
               account for a large percentage of prescriptions filled for 
               these medications 

             CHBRP maintains that oral anticancer medications are used to 
               treat frequently diagnosed cancers, such as breast, lung, 
               prostate, and colorectal cancers.  CHBRP notes that they 
               are also used for rare cancers, such as cancer of the 
               adrenal gland, cancer of the dermis layer of the skin and 
               eye cancer.  Some oral anticancer medications are used 
               alone, whereas others are used in combination with IV 
               medication.  Still others are used alone or in combination 
               with other anticancer medications depending on the cancer 
               they are being used to treat or the severity or stage of 
               the cancer.  

             When compared to IV and injectable anticancer medications, 
               oral anticancer medications have both advantages and 
               disadvantages.  According to CHBRP, advantages include that 
               oral anticancer medications may allow administration of the 
               medication on a daily basis; may be more convenient for 
               patients; and, may reduce the risk of infection or other 
               infiltration complications.  Disadvantages include less 
               certainty in patient adherence to treatment regimens and a 
               reduction in interaction between patients and their health 
               care providers to manage complications of treatment. 

              b)   Benefit Coverage, Utilization, and Cost Impacts  .  








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               According to CHBRP, this bill would affect the coverage of 
               approximately 20.1 million enrollees in DMHC-regulated 
               health plans and CDI-regulated health insurance policies in 
               California with outpatient prescription drug coverage.  
               This excludes the estimated 968,000 enrollees who do not 
               have outpatient prescription drug coverage and about 
               831,000 enrollees in plans purchased by CalPERS, which are 
               exempt from the provisions of this bill.  CHBRP notes that 
               97.4% of the 20.1 million enrollees are estimated to have 
               coverage for nongeneric oral anticancer medications and 
               approximately 2.6% of these enrollees have no coverage for 
               outpatient oral nongeneric anticancer medications, because 
               they have generic-only coverage.  

             CHBRP estimates that 0.3% of enrollees with coverage subject 
               to this bill will use nongeneric oral anticancer 
               medications in a year.  CHBRP does not estimate a 
               measurable increase in the number of oral anticancer 
               medications users nor a measurable increase in the number 
               of prescriptions.

             According to CHBRP, this bill would shift some nongeneric 
               oral anticancer medication costs from users to health plans 
               and insurers through reduced cost sharing.  CHBRP, states 
               that, in total, users would see a reduction in 
               out-of-pocket costs of an estimated $2,650,000 due to 
               lesser cost-sharing requirements.  On average the amount of 
               the shift is estimated to be $100.28 per user per year.  
               This bill is expected to increase premiums by about 
               $3,137,000 (0.0036%).

              c)   Public Health Impacts  .  CHBRP does not project a 
               measurable increase in utilization of oral anticancer 
               medications as a result of this bill.  Therefore, according 
               to CHBRP, the only potential public health impact of this 
               bill is the reduction in out-of-pocket costs for oral 
               anticancer medications.  CHBRP maintains that this could 
               reduce the financial burden and related health consequences 
               face by cancer patients.  

             CHBRP reports that, nearly one in two Californians born today 
               will develop cancer at some point in their lifetime.  There 
               are an estimated 144,000 cases of cancer diagnosed each 
               year, while approximately 1.2 million Californians alive 
               today have a history with the disease.  According to CHBRP, 








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               breast cancer is the most prevalent cancer in California, 
               almost exclusively affecting women.  CHBRP asserts that 70% 
               of the prescriptions and 31% of the total cost for 
               nongeneric oral anticancer medications are for drugs used 
               to treat breast cancer.  Therefore, to the extent that this 
               bill reduces out-of-pocket costs for patients, there is the 
               potential to reduce the financial burden faced by women 
               undergoing treatment for breast cancer.

             After breast cancer, according to CHBRP, the next three most 
               common cancers in California are colorectal, prostate, and 
               lung cancer.  Non-Hispanic blacks in California have higher 
               rates of diagnoses of these three cancers compared to all 
               other racial and ethnic groups.  These three cancers are 
               all treated using oral nongeneric anticancer medications; 
               therefore, to the extent that this bill reduces 
               out-of-pocket costs for oral anticancer medications, CHBRP 
               maintains, non-Hispanic black cancer patients could face a 
               reduced financial burden.


           4)EHBs  .  The PPACA requires qualified health plans to cover 
            specified categories of EHBs, including behavioral health 
            treatment and rehabilitative services, by 2014.  The HHS 
            Secretary is tasked with defining these benefit categories 
            through regulation so that they mirror those benefits offered 
            by a "typical" employer plan.  Qualified plans are required to 
            cover EHBs by 2014.  Federal guidance with respect to EHBs is 
            expected later this year and in 2012.

          In a January 2011 issue brief by CHBRP focusing on the federal 
            requirement to cover EHBs, CHBRP notes that there is 
            considerable legal ambiguity over how state mandates requiring 
            the coverage of the treatment for a specific condition or 
            disease will interact with federal law.  CHBRP states that 
            these mandates often extend across multiple benefit 
            categories.  CHBRP cites, as an example, California's mandate 
            to cover breast cancer treatment, which implicitly requires 
            coverage for screening and testing, medically necessary 
            physician services, ambulatory services, prescription drugs, 
            hospitalization, and surgery.  CHBRP writes that it is unclear 
            how California benefit mandates that overlap across several 
            EHB categories would be evaluated in relation to the EHB 
            package.









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           5)SUPPORT  .  According to Carrie's TOUCH, Inc. (Carrie's TOUCH), 
            the sponsors of this bill, the emergence of clinically safe 
            and effective, orally administered anticancer medication has 
            significantly increased the treatment options for cancer 
            patients.  Carrie's TOUCH maintains that there is a disparity 
            that exists between the medical and pharmacy benefit design 
            creating greater out-of-pocket responsibilities for oral 
            anticancer treatment covered under the pharmacy benefit than 
            the out of pocket costs for IV treatment covered under the 
            medical benefit.  Carrie's TOUCH argues that the cost barriers 
            currently impede access to orally administered cancer 
            treatment.  The American Cancer Society (ACS) states that 
            patients using oral chemotherapy generally experience milder 
            side effects and avoid the need for transportation back and 
            forth to chemotherapy appointments, which, depending on a 
            patient's circumstances can be onerous for the patient and the 
            caretakers.  ACS further states that many oral chemotherapy 
            treatments do not have IV counterparts, making the need to 
            ensure access to them critical.  AstraZeneca argues in support 
            that access to effective medicines, including oral and IV 
            therapies, should be determined by medical appropriateness - 
            as determined by a physician in consultation with a patient.  
            AstraZeneca asserts that ensuring oral chemotherapy agents are 
            covered in a similar manner as intravenous therapies helps to 
            ensure that a physician has all of the necessary tools 
            available to help patients and their family caregivers.  

          6)OPPOSITION  .  The California Association of Health Plans, the 
            California Chamber of Commerce, and America's Health Insurance 
            Plans all write in opposition that, while well intentioned, 
            this bill would further exacerbate the problem of rising 
            health care costs.  The opposition maintains that this bill 
            may only minimally increase health insurance premiums, but 
            this increase cannot be viewed in isolation.  The opposition 
            argues that this year alone the Legislature will be 
            considering at least a dozen new mandates along with the many 
            currently imposed benefit mandates.  These mandates, according 
            to the opposition, have reduced flexibility in benefit design, 
            increased health care costs, and premium rates leading to 
            reduced employers' and individuals choice of benefit packages, 
            ultimately contributing to the need for health care reform 
            today.  The opposition asserts that benefit mandates make 
            insurance less affordable, resulting in an increased number of 
            uninsured.  
           








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           7)PREVIOUS LEGISLATION  .

             a)   SB 961 (Wright) of 2010, contained identical language as 
               this bill and was vetoed by Governor Arnold Schwarzenegger 
               stating his concern about adding costs to increasingly 
               expensive health insurance premiums.  Governor 
               Schwarzenegger also stated that in light of federal health 
               reform this bill was unnecessary.

             b)   SB 161 (Wright) of 2009, was substantially similar to 
               this bill, and would have required a carrier contract or 
               policy that provides coverage for anticancer treatment to 
               provide coverage for a prescribed, orally administered 
               anticancer medication on a basis "no less favorable" than 
               IV or injected anticancer medications.  SB 161 was vetoed 
               by Governor Arnold Schwarzenegger stating that SB 161 
               limits a carrier's ability to control both the 
               appropriateness of the care and the cost by requiring them 
               to immediately cover every medication as soon as it 
               receives federal approval, regardless of the provisions of 
               the carrier's formulary, placing carriers at a severe 
               disadvantage when negotiating prices with drug 
               manufacturers.  The Governor further stated his belief that 
               oral anticancer medications were more cost-effective and 
               efficacious in some instances and encouraged the author, 
               for reconsideration this year, to collaborate with his 
               Administration, carriers, and the pharmaceutical 
               manufacturers to explore whether there were ways to provide 
               greater access without increasing costs.  
           
           8)POLICY COMMENT  .  This bill is one of several health mandates 
            introduced for legislative consideration this year.  The 
            author may wish to address the extent to which the need for 
            this bill and others similar to it is premature, given that 
            federal regulations to define the parameters of the EHB 
            package have yet to be promulgated.

          REGISTERED SUPPORT / OPPOSITION  :   

           Support  
          Carrie's Touch, Inc. (sponsor)
          American Cancer Society, California Division
          Association of Northern California Oncologists
          AstraZeneca








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          BayBio
          BIOCOM
          California Affiliates of Susan G. Komen for the Cure
          California Children's Hospital Association
          California Healthcare Institute
          California Medical Association
          City of West Hollywood
          International Myeloma Foundation
          Leukemia & Lymphoma Society

           Opposition  
          America's Health Insurance Plans
          Association of California Life & Health Insurance Companies
          California Association of Health Plans
          California Chamber of Commerce  
          Analysis Prepared by  :    Tanya Robinson-Taylor / HEALTH / (916) 
          319-2097