BILL ANALYSIS                                                                                                                                                                                                    �






                             SENATE JUDICIARY COMMITTEE
                             Senator Noreen Evans, Chair
                              2011-2012 Regular Session


          AB 2356 (Skinner)
          As Amended May 30, 2012
          Hearing Date: July 3, 2012
          Fiscal: No
          Urgency: No
          NR   
                    

                                        SUBJECT
                                           
                                   Tissue Donation

                                      DESCRIPTION 

          Existing law prohibits the transfer of any tissues, including 
          sperm, into the body of another person by means of 
          transplantation, unless the donor of the tissues has been 
          screened and found nonreactive for evidence of infection with 
          human immunodeficiency virus (HIV), agents of viral hepatitis 
          (HBV and HCV), syphilis, and human T-lymphotrophic virus (HTLV), 
          except as provided.  Sperm from anonymous donors is also subject 
          to repeat testing and quarantine requirements.  

          This bill would except sperm donated by a sexually intimate 
          partner of the recipient from second or repeat testing, if the 
          recipient is informed of the testing requirements and signs a 
          written waiver, as specified. 

          This bill would immunize a physician or surgeon for liability 
          based solely upon the use of sperm from a sexually intimate 
          partner of a recipient who has given informed consent to waive 
          repeat testing, as specified.  This bill would also prohibit 
          disciplinary action against a physician and surgeon solely 
          because the physician and surgeon used sperm under these 
          conditions. 

          This bill would also provide that its provisions do not create a 
          duty for a physician or surgeon to use sperm from a sexually 
          intimate partner if the physician determines that the 
          insemination or services do not meet specified guidelines for 
          providing insemination or advanced reproductive technology 
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          services. 

                                      BACKGROUND  

          Infertility is defined by the Centers for Disease Control and 
          Prevention as not being able to get pregnant after one year of 
          trying, or, six months, if a woman is 35 years or older. Women 
          who can get pregnant but are unable to stay pregnant may also be 
          infertile. Many women are now waiting late in life to have 
          children.  Because about one-third of couples in which the woman 
          is older than 35 years have fertility problems, infertility is a 
          growing concern.  Infertility may be treated with medicine, 
          surgery, artificial insemination, assisted reproductive 
          technology, or a combination of these treatments. Unlike other 
          areas of medicine, which are regulated predominately at the 
          state level, assisted reproductive technologies are also 
          regulated at the federal level.  In addition, the state 
          regulates physicians and tissue banks that deal with sperm, and 
          professional associations have extensive professional guidelines 
          for the use of sperm.  
          The Society for Assisted Reproductive Technology (SART) and the 
          American Society for Reproductive Medicine (ASRM), jointly 
          offered guidelines for sperm donation in 2008 that are widely 
          followed.  Among the recommended laboratory tests were those for 
          HIV, HBV, HCV, syphilis, and HTLV. The guidelines made specific 
          recommendations for anonymous donation, donation from a known 
          source, and sexually intimate couples. The guidelines provide 
          that anonymous donors are tested and re-tested, which is also 
          required under regulations issued by the Food and Drug 
          Administration.  Thus, if an initial donation produces negative 
          results, the semen samples should be collected, cryopreserved, 
          and quarantined for a minimum of 180 days, after which the semen 
          should be retested, and again found negative, before the samples 
          may be released.  Directed, or known donors should undergo the 
          same screening and testing as anonymous donors, and directed 
          donor specimens are treated in the same manner as anonymous 
          donor specimens.  Sexually intimate couples seeking fertility 
          treatment, however, are only advised to undergo testing to 
          minimize the risk of viral transmission to partners and 
          resulting children.  Under these guidelines, sperm donated from 
          a sexually intimate partner is not required to be quarantined or 
          undergo repeat testing. 

          This bill would, for the purposes of the bill, define "sexually 
          intimate partner of the recipient" to include a known or 
          designated donor to whose sperm the recipient has previously 
                                                                      



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          been exposed in a nonmedical setting in an attempt to conceive, 
          and permit that recipient to waive a second or repeat testing of 
          that donor.  This bill would exempt a physician who has obtained 
          informed consent from the recipient, from liability or 
          discipline based solely upon the use of sperm from a sexually 
          intimate partner of the recipient. 

                                CHANGES TO EXISTING LAW
           
           Existing federal law  establishes procedures to prevent the 
          introduction, transmission, and spread of communicable diseases 
          by human cells, tissues, and cellular and tissue-based products 
          (HCT/Ps). Federal law defines HCT/Ps as "articles containing or 
          consisting of human cells or tissues that are intended for 
          implantation, transplantation, infusion, or transfer into a 
          human recipient, including semen or other reproductive tissue." 
          (21 C.F.R. Sec. 1270.1 et seq.)
             
           Existing federal law  authorizes the Food and Drug Administration 
          (FDA) to regulate establishments that engage in the manufacture 
          of HCT/Ps. (21 C.F.R. Sec. 1271.1.)
           
          Existing federal law  requires all donors of cells and tissues 
          used in HCT/Ps to be screened and tested for relevant 
          communicable disease agents and diseases, and prohibits the 
          implantation, transplantation, infusion, or transfer of HCT/Ps 
          until the donor has been determined to be eligible, with 
          specified exemptions. (21 C.F.R. Sec. 1271.45.)

           Existing federal law  requires, before the completion of a 
          donor-eligibility determination that:
           a donor's medical records be screened for specified risk 
            factors and evidence of relevant communicable diseases;
           the semen from anonymous donors be quarantined in a physically 
            separate area clearly identified for such use for at least six 
            months after the date of donation; and 
           semen from anonymous donors be retested by collecting a new 
            specimen from the donor and testing it for evidence of 
            infection due to HIV, HBV and HCV, syphilis, and HTLV. (21 
            C.F.R. Sec. 1271.75.)

           Existing federal law  exempts reproductive cells or tissue 
          donated by a sexually intimate partner of the recipient for 
          reproductive use from specified donor eligibility requirements. 
          (21 C.F.R. Sec. 1271.90.)
          
                                                                      



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           Existing law prohibits the transfer of any tissues into the body 
          of another person by means of transplantation, unless the donor 
          of the tissues has been screened and found nonreactive by 
          laboratory tests for evidence of infection with HIV, HBV, HCV, 
          syphilis, and HTLV, subject to specified exemptions. (Health & 
          Saf. Code Sec. 1644.5 (a).)

           Existing law  permits a recipient of sperm, from a sperm donor 
          known to the recipient, to waive a second or other repeat 
          testing of that donor if the recipient is informed of specified 
          requirements for testing donors and signs a written waiver. 
          (Health & Saf. Code Sec. 1644.5 (c).)

           This bill  would define, for the purposes of this bill, a 
          "sexually intimate partner of the recipient" to include a known 
          or designated donor to whose sperm the recipient has previously 
          been exposed in a nonmedical setting in an attempt to conceive.
           
          This bill  would authorize the recipient of sperm donated by a 
          sexually intimate partner for reproductive use to waive a second 
          or repeat testing of that donor for HIV, HBV, HCV, syphilis, and 
          HTLV, if the recipient is informed of existing donor testing 
          requirements and signs a written waiver.

           This bill  would exempt a physician, when the physician provides 
          insemination or advanced reproductive technology services and 
          has obtained the informed consent of the recipient, who 
          acknowledges and accepts the risks of using sperm that has not 
          undergone quarantine and repeat testing, as specified, from:
           liability for damages for any cause of action based solely on 
            the use of sperm donated by a SIP of the recipient; and
           disciplinary action against his or her professional license 
            and peer review by a professional organization peer review 
            body, as defined.

           This bill  would exempt a clinical laboratory or tissue bank, as 
          specified, from disciplinary action against its license because 
          of the use of sperm donated by a sexually intimate partner of 
          the recipient when any physician affiliated with the clinical 
          laboratory or tissue bank has obtained the informed consent of 
          the recipient, who acknowledges and accepts the risks of using 
          sperm that has not undergone quarantine and repeat testing, as 
          specified.
                
          This bill  would prohibit any provisions in the bill from 
          creating a duty for a physician to use sperm donated by a 
                                                                      



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          recipient's sexually intimate partner in providing insemination 
          or advanced reproductive technology services if the physician 
          reasonably concludes that the insemination or services do not 
          meet the American Society for Reproductive Medicine guidelines 
          for gamete and embryo donation.  This bill would further 
          prohibit anything in this bill from being construed to affect 
          any liability that may be imposed pursuant to federal rule or 
          regulation when a physician, clinical laboratory, or tissue bank 
          provides insemination or advanced reproductive technology 
          services.

                                        COMMENT
           
           1.Stated need for the bill
           
          According to the author: 

             Single women and same sex couples using a known donor do not 
             get the same insemination treatment as women with a male 
             partner when trying to conceive.  A woman who receives 
             fertility services with a male is able to use fresh sperm for 
             insemination, greatly increasing the likelihood of the woman 
             conceiving.  A woman who receives fertility services with a 
             known male donor can only receive frozen sperm, reducing her 
             chances of conceiving. . . . Not only is frozen sperm less 
             effective, but the six month waiting period can reduce the 
             chance of becoming pregnant for women over 40.  Insemination 
             with frozen sperm is also significantly more expensive than 
             insemination with fresh sperm. 

           2.Physician and surgeon immunity

           This bill would exclude a physician or surgeon from liability or 
          disciplinary action based solely upon the use of sperm from a 
          sexually intimate partner where the recipient waived repeat 
          testing, if the physician or surgeon has obtained informed 
          consent. This bill would also provide that its provisions do not 
          create a duty for a physician or surgeon to use sperm from a 
          sexually intimate partner if the physician determines that the 
          insemination or services do not meet specified guidelines for 
          providing insemination or advanced reproductive technology 
          services.  

          Staff notes that civil immunity provisions are rarely preferable 
          because they, by their nature, prevent an injured party from 
          seeking a particular type of recovery.  However, the immunity 
                                                                      



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          provisions under this bill are arguably appropriate because they 
          are narrowly tailored and mirror similar provisions of 
          applicable law. 
           
           California law authorizes a recipient using sperm from a "known 
          donor" to waive repeat testing.  Federal regulations similarly 
          allow a waiver if the recipient is a "sexually intimate partner" 
          of the donor.  Yet neither state nor federal law defines these 
          terms.  At least in part, the ability to waive repeat testing 
          seems to be based on a social expectation that couples are 
          monogamous. Thus, repeat testing which may reveal diseases or 
          infections that the donor contracted since the initial testing 
          need not be required.  On this point, the co-sponsors argue that 
          in practice, there is a "disparity between different-sex couples 
          and same-sex or single women using known donors when they may 
          need to seek fertility services in a medical setting after 
          failed attempts to conceive at home.  Whereas different-sex 
          couples are permitted to use fresh sperm to inseminate when 
          using fertility services, all other women must typically have 
          their donor's sperm frozen and quarantined for up to six months 
          to allow for repeated donor screening for sexually transmitted 
          diseases.  Yet, women who have attempted to inseminate at home 
          with a designated donor are exposed to exactly the same risk of 
          disease transmission as women who have sex with male partners to 
          conceive."

          While no specific "immunity" language exists under current law 
          with respect to a recipient's ability to waive repeat testing, 
          there is an informed consent requirement.  Because informed 
          consent essentially requires that the recipient assume at least 
          some of the risks involved in the procedure consented to, 
          physicians are arguably already protected to some degree by that 
          consent.  For example, there is no guarantee that the male 
          partner in a same-sex couple will remain monogamous.  Therefore, 
          if his partner, the recipient, waives repeat testing through 
          informed consent, she will not be able to sue the physician for 
          malpractice if she contracted a disease from the sperm, or if 
          the resulting child is born inflicted by an infection or disease 
          that the donor-father contracted after the first round of 
          testing. 

          Yet, if the assisted reproduction process was affected in a way 
          unrelated to the fact that the sperm had not been re-tested, a 
          recipient could still have a cause of action.  This is true 
          under existing law and the provisions of this bill.  For 
          example, if the physician failed to conduct the initial tests on 
                                                                      



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          the donor sperm, or inadvertently switched sperm, the 
          recipient's ability to seek damages would not be limited by the 
          fact that she waived repeat testing. 

          Further, this bill does not create a duty for a physician to use 
          sperm that has not been retested if the physician concludes that 
          doing so would render his or her reproductive technology 
          services in violation of federal guidelines.  As noted by the 
          California Medical Association in support: 

             When this bill was first introduced, many of our members had 
             concerns about the potential impacts this bill may have on 
             physicians who chose to either follow these new provisions or 
             continue to follow federal guidelines.  To address our 
             concerns, the author amended the bill by adding specific 
             provisions to protect physicians from liability for their 
             actions, including requiring that the recipient received 
             informed consent and an assumption of the risk. 
           
           The narrow immunity that this bill provides mirrors the 
          protections offered to physicians when same-sex couples waive 
          repeat testing, and in no way limits a physician's liability for 
          negligence or malpractice in the general administration of 
          assisted reproductive technologies.  Further, this bill imposes 
          no duty upon the physician to act if he or she concludes that 
          doing so would be in violation of federal guidelines.   
                                                                 
           3.Informed consent

           Existing California law authorizes a recipient of sperm from a 
          known donor to waive a second or other repeat testing if the 
          recipient is informed of the requirements for testing and signs 
          a written waiver.  Existing federal law authorizes a recipient 
          to waive repeat testing only if the donor is a sexually intimate 
          partner of the recipient.  This bill would define a sexually 
          intimate partner, for the purposes of this bill only, as a known 
          or designated donor to whose sperm the recipient has already 
          been exposed in a nonmedical setting.  By including a definition 
          of sexually intimate partner in California law, this bill would 
          authorize waiver of repeat testing, arguably in compliance with 
          federal law as well. 

          Current law places the obligation on a physician to obtain 
          "informed consent" from a patient prior to a treatment or 
          procedure.  First used in Salgo v. Leland Stanford Jr. 
          University Board of Trustees (1957) 154 Cal.App.2d 560 and 
                                                                      



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          followed by Cobbs v. Grant (1972) 8 Cal.3d 229, the principle of 
          "informed consent" has been fine-tuned, but not varied, by more 
          recent cases.  The American Medical Association writes that 
          informed consent is "more than simply getting a patient to sign 
          a written consent form. It is a process of communication between 
          a patient and physician that results in the patient's 
          authorization or agreement to undergo a specific medical 
          intervention.  In the communications process ? the patient 
          should have an opportunity to ask questions to elicit a better 
          understanding of the treatment or procedure, so that he or she 
          can make an informed decision to proceed or to refuse a 
          particular course of medical intervention." (American Medical 
          Association,  �as of June 29, 2012].)

          Thus, the obligation to ensure that the recipient is given 
          material information about the nature, associated and inherent 
          risks, and other important and material facts about waiving 
          repeat testing of donor sperm is the responsibility of the 
          physician providing the insemination or advanced reproductive 
          technology services.  This bill would require the physician to 
          inform the recipient of the donor testing requirements.  The 
          recipient must then acknowledge and accept the risks of using 
          sperm that has not undergone quarantine and repeat testing 
          before she may waive the repeat testing requirements.  Because 
          this information is material to a recipient's decision whether 
          to accept or reject the reproductive treatment under question, 
          it is entirely consistent with statutory, regulatory, and 
          decisional law on informed consent.
           
          4.Technical amendments 

           Due to procedural timing constraints, the following author's 
          amendments were agreed to in the Senate Health Committee with a 
          commitment that they would be taken in this Committee.
           
            Author's amendments
              
             Change references from "advanced reproductive technology" and 
            "advanced reproductive technologies" to "assisted reproductive 
            technology" and "assisted reproductive technologies".

            On Page 3, Lines 20-21, strike out "includes any woman who has 
            been exposed to the donor's sperm outside of a medical 
            setting" and insert "includes a known or designated donor to 
                                                                      



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            whose sperm the recipient has previously been exposed in a 
            nonmedical setting in an attempt to conceive".


           Support  :  ACLU of California; ACLU, Paul Robeson Chapter; 
          American Federation of State, County and Municipal Employees, 
          AFL-CIO; API Equality-Northern California; Asian & Pacific 
          Islander Wellness Center; At Home Fertility ; California Medical 
          Association; Colage; GroundSpark; Kaiser Permanente; L.A. Gay & 
          Lesbian Center; Laparoscopic Institute for Gynecologic Oncology; 
          Our Family Coalition; Rainbow Flag Health Services; Somos 
          Familia; Tres Lunas Midwifery ; Betty T. Yee, First District 
          Member, BOE; Two individuals

           Opposition  :  California Right to Life Committee, Inc.

                                        HISTORY
           
          Source  :  Equality California; National Center for Lesbian Rights

           Related Pending Legislation  :  None Known

           Prior Legislation  :

          AB 1487 (Hill, Chapter 444, Statutes of 2010) required testing 
          for evidence of infection with HTLV, as specified, until January 
          1, 2014, at which point regulations must be adopted by the State 
          Department of Public Health.  
          AB 1397 (Hill, 2009) was substantially similar to AB 1487 but 
          was vetoed by the Governor who found that some of the provisions 
          inappropriately restricted the administrative and regulatory 
          authority of the Department of Public Health.  

          SB 1184 (Kuehl, Chapter 347, Statutes of 2008), required a 
          physician providing assisted reproductive technologies to verify 
          and document in the recipient's medical record, that the donor 
          of sperm who tests reactive for HIV or HTLV-1 is under the care 
          of a physician managing the HIV or HTLV-1 to minimize the risk 
          of transmission during the course of insemination or ART 
          services.

          SB 443 (Migden, Chapter 207, Statutes of 2007) authorized the 
          use of sperm whose donor has tested reactive for HIV or HTLV-1 
          for the purposes of insemination or ART only after the donor's 
          sperm has been effectively processed to minimize the 
          infectiousness of the sperm, as specified, and with informed and 
                                                                      



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          mutual consent. 

          AB 441 (Richter and Mazzoni, Chapter 511, Statutes of 1997), 
          created an exception to the prohibition on the transfer of 
          tissues into another person unless the tissue donor has been 
          screened and found nonreactive for evidence of infection, as 
          specified, if the sperm donor is the spouse, partner, or 
          designated donor of the recipient, and if certain other 
          conditions are met.

          AB 525 (Speier, Chapter 659, Statutes of 1993), authorized the 
          recipient of sperm, from a donor known to the recipient, to 
          waive a second or repeat screening of that donor if the 
          recipient is informed of the requirements for testing donors 
          under California law and signs a written waiver.

           Prior Vote  :

          Senate Committee on Health (Ayes 6, Noes 2)
          Assembly Floor (Ayes 50, Noes 24) 
          Assembly Committee on Health (Ayes 13, Noes 5)

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