BILL ANALYSIS                                                                                                                                                                                                    �



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          ASSEMBLY THIRD READING
          AJR 50 (Bloom)
          As Amended August 20, 2014
          Majority vote 

           JUDICIARY           8-2                                         
           
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          |Ayes:|Wieckowski, Alejo, Chau,  |     |                          |
          |     |Dickinson, Garcia,        |     |                          |
          |     |Maienschein, Muratsuchi,  |     |                          |
          |     |Stone                     |     |                          |
          |     |                          |     |                          |
          |-----+--------------------------+-----+--------------------------|
          |Nays:|Wagner, Gorell            |     |                          |
          |     |                          |     |                          |
           ----------------------------------------------------------------- 
           SUMMARY  :  Requests the President and the Department of Health  
          and Human Services to adopt science-based policies that repeal  
          current Food and Drug Administration (FDA) policies that  
          prohibit men who have had sex with men (MSM) from donating  
          blood.  Specifically,  this resolution  :   

          1)Declares that California law prohibits discrimination against  
            individuals on the basis of actual or perceived sex, sexual  
            orientation, gender identity, and gender-related appearance  
            and behavior.

          2)Finds that current FDA policy effectively prohibits any man  
            who has had sex with another man even one time since 1977 from  
            donating blood for the rest of his life, and that the FDA  
            essentially classifies all sexually active gay and bisexual  
            men in the highest-risk blood donor category, the same  
            category as Intravenous drug users and people who have spent  
            more than five years since 1980 in a country that has mad cow  
            disease.

          3)Declares that the American Red Cross (ARC), the American  
            Association for Blood Banks (AABB), and America's Blood  
            Centers (ABC), at a 2006 workshop convened by the FDA, issued  
            a joint statement that they believe the current blood donation  
            policy of lifetime deferral for men who have had sex with men  
            is medically and scientifically unwarranted, and calling for  
            deferral criteria to be made comparable with criteria for  








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            other groups at increased risk for sexual transmission of  
            infections that can be transmitted through blood transfusion.

          4)Asserts that it does not appear rational to broadly  
            differentiate sexual transmission via responsible male-to-male  
            sexual activity from transmission via responsible heterosexual  
            activity on scientific grounds, and that to many, this  
            differentiation is unfair, creates stigma without any  
            justifiable public health imperative, and fosters negative  
            attitudes towards blood collection facilities and the  
            eligibility criteria they use to screen donors.

          5)Finds that many men who have sex with men are healthy, present  
            no risk of introducing HIV or other infectious agents into the  
            nation's blood supply, and wish to be blood donors without  
            compromising the safety or reliability of the blood supply.

          6)States that FDA guidelines followed by blood banks throughout  
            the country inadvertently create unjustified stigma directed  
            towards men who have had sex with other men, and that these  
            guidelines conflict with state nondiscrimination policies.

          7)Calls upon the President to encourage, and the Secretary of  
            the United States Department of Health and Human Services to  
            adopt, policies that repeal current donor suitability and  
            deferral policies of the FDA prohibiting blood donation by men  
            who have had sex with men, and instead direct the FDA to  
            develop science-based policies.

           FISCAL EFFECT  :  None

           COMMENTS  :  This resolution, sponsored by Equality California,  
          respectfully requests the President and the Department of Health  
          and Human Services to adopt policies that repeal current Food  
          and Drug Administration policies that prohibit MSM from donating  
          blood.  The author believes that the current FDA policy is  
          unnecessary given improvements in donor screening techniques,  
          and operates in an unfair and discriminatory manner against  
          homosexual men as a group because of their status, without  
          regard to whether screening of individual donors indicates any  
          risk of transmitting disease via blood transfusion.  According  
          to the author, the FDA policy is "an outdated and discriminatory  
          policy that should be replaced scientific evidence-based  
          practices for collecting and testing donated blood."








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          According to the FDA, MSM at any time since 1977 are deferred as  
          blood donors because, as a group, MSM are at increased risk for  
          HIV, hepatitis B, and other infections that can be transmitted  
          by blood transfusion.  The year 1977 was chosen because it  
          marked the beginning of the AIDS epidemic in the United States.   
          Although the FDA policy uses the term "deferral," the policy in  
          effect acts to prohibit, in all cases, men who have had sex with  
          men since 1977 from donating blood.

          The FDA has had a donor deferral policy for MSM since 1983, when  
          the risk of AIDS from transfusion was first recognized.  On  
          April 23, 1992, the FDA issued a memorandum (also known as a  
          "guidance document") to all blood donation establishments titled  
          Revised Recommendations for the Prevention of Human  
          Immunodeficiency Virus Transmission by Blood and Blood Products.  
           As is common in administrative law, the agency issued this  
          memorandum to those in the regulated community to provide  
          guidance and more detailed instruction on how to comply with  
          federal law and regulations.  The specific rules in such a  
          memorandum can and often do have the effect of agency policy.   
          In this case, the current FDA policy deferring blood donation by  
          MSM traces back to that 1992 memorandum and has remained in  
          effect since that time.

          According to the FDA Web site, the primary responsibility of the  
          agency is to enhance blood safety and protect blood recipients,  
          and its MSM deferral policy is intended to protect all people  
          who receive blood transfusions from an increased risk of  
          exposure to blood potentially infected with certain  
          disease-causing agents, including HIV, the virus that causes  
          AIDS.  The FDA cites a variety of epidemiological and scientific  
          data to justify its current MSM deferral policy, including that:  
           1) Men who have had sex with men since 1977 have an HIV  
          prevalence 60 times higher than the general population and 800  
          times higher than first time blood donors; 2) MSM account for  
          the single largest group of blood donors who are found  
          HIV-positive by blood donor testing; and 3) Even the latest  
          blood testing technology cannot detect very low levels of HIV  
          present in the blood during the short "window period" right  
          after infection but before HIV tests can detect the virus.  The  
          FDA has stated it would change its MSM deferral policy "only if  
          supported by scientific data showing that a change in policy  
          would not present a significant and preventable risk to blood  








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          recipients."  

          On March 8, 2006, the FDA conducted a workshop entitled  
          Behavior-Based Donor Deferrals in the Nucleic Acid Test (NAT)  
          Era.  The workshop addressed scientific challenges,  
          opportunities, and risk-based donor deferral policies relevant  
          to the protection of the blood supply from transfusion  
          transmissible diseases, seeking input on this topic.   
          Participants were given the opportunity to provide scientific  
          data that could support revising FDA's MSM deferral policy.  At  
          that workshop, three major blood collection agencies, the ARC,  
          the AABB, and ABC, testified before the FDA's Blood Products  
          Advisory Committee.  These organizations recommended that the  
          deferral period for MSM be changed to 12 months since last  
          sexual contact, which would make this consistent with the  
          deferral periods for other potentially high risk sexual  
          exposures.  Except during the window period right after  
          infection, the agencies stated that there is no valid scientific  
          reason to differentiate between individuals infected a few  
          months or many years previously.  Furthermore, the agencies  
          cited new evidence showing that the vast majority of donors with  
          prevalent HIV infection will test positive by both serologic  
          testing and the NAT method, thus assuring redundancy in  
          laboratory screening that all donated blood undergoes.  As a  
          result, according to the agencies, the small risk to recipients  
          posed by false negative screening in the laboratory is very  
          minimal.

          According to the blood collection agencies, the proper  
          scientific basis for FDA's policy specifying deferral periods  
          for certain at-risk sexual behaviors should be the length of  
          window periods for laboratory testing, not the initial mode or  
          time of HIV infection (unless the infection is so recent as to  
          have occurred within the critical window period.)  The agencies  
          argue that the proper focus of the screening questions should be  
          on recent risk history of possible infection, particularly as  
          that interacts with the window period for lab testing methods,  
          and they point out that this is already true for many other  
          screening questions not related to MSMs.  The author notes that  
          the American Medical Association (AMA) House of Delegates and  
          the HIV Medicine Association (part of the Infectious Diseases  
          Society of America) have joined the three major blood collection  
          agencies in adopting the position that scientific knowledge of  
          HIV transmission and blood testing methods now justifies  








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          revising the FDA deferral policy with respect to MSM. 

          Following the 2006 workshop, however, the FDA disagreed with the  
          scientific positions of the blood collection agencies and  
          declined to change its deferral policy for MSMs, stating on its  
          Web site: "Scientific evidence has not yet been provided to FDA  
          that shows that blood donated by MSM or a subgroup of these  
          potential donors, is as safe as blood from currently accepted  
          donors.  FDA remains willing to consider new approaches to donor  
          screening and testing, provided those approaches assure that  
          blood recipients are not placed at an increased risk of HIV or  
          other transfusion transmitted diseases."

          Under current FDA policy, potential blood donors judged to be at  
          risk for exposure via heterosexual routes are deferred for only  
          one year, while men who have had sex with another man even once  
          since 1977 are permanently deferred.  The author believes the  
          FDA is not justified in broadly differentiating sexual  
          transmission via male-to-male sexual activity from that via  
          heterosexual activity.  As the measure states: "Even with a  
          clean bill of health, a gay man is considered more of a threat  
          to the blood supply than a straight man who was treated for  
          chlamydia, syphilis, gonorrhea, venereal warts, and genital  
          herpes within the past year.  In 40 states, a man can even give  
          blood immediately following a tattoo or 12 months after having  
          sex with a prostitute."  Furthermore, the author contends that  
          not only do current FDA guidelines conflict with state  
          nondiscrimination policies, but they also may "inadvertently  
          create unjustified stigma directed towards gay, bisexual,  
          transgender, and heterosexual males on the basis that they have  
          had sex with another male since 1977."  According to comments  
          made by Dr. Ronald Bayer of Columbia University at the FDA  
          workshop in 2006, this threat of stigmatization is something  
          that has concerned gay advocates ever since the FDA first  
          implemented its lifetime deferral policy for MSM in 1983.  

          In summary, supporters of the resolution believe that the FDA  
          deferral policy is outdated and should be changed to reflect  
          accepted science about the safety of blood donated by MSM as  
          compared to other donor sources.  There is compelling evidence  
          to suggest that this is the case.  The resolution also  
          acknowledges social and political reasons that support changing  
          the FDA policy.  Proponents favor implementing a policy that  
          takes into account the individual risk factors associated with  








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          the sexual activity of a potential donor, regardless of his  
          sexual orientation, and believe such a policy would reflect the  
          spirit, if not the letter, of state anti-discrimination law,  
          while reflecting sound scientific principles.  In addition, that  
          policy would presumably alleviate the fear of stigmatization,  
          long held by members of the gay community, associated with the  
          lifetime blood donation ban imposed on men who have sex with  
          other men.


           Analysis Prepared by  :   Anthony Lew / JUD. / (916) 319-2334 


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