BILL ANALYSIS                                                                                                                                                                                                    �







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        |Hearing Date:January 13, 2014      |Bill No:AB                         |
        |                                   |467                                |
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                      SENATE COMMITTEE ON BUSINESS, PROFESSIONS 
                               AND ECONOMIC DEVELOPMENT
                              Senator Ted W. Lieu, Chair
                                           

                          Bill No:        AB 467Author:Stone
                   As Amended:January 7, 2014         Fiscal:  Yes 

        
        SUBJECT:  Prescription drugs: collection and distribution program. 
        
        SUMMARY:  An urgency measure which establishes a licensure category  
        for a surplus medication collection and distribution intermediary  
        established for the purpose of facilitating the donation of  
        medications to, or transfer of medications between, participating  
        entities under a county's unused medication repository and  
        distribution program.   

        Existing law, the Business and Professions Code (BPC):
        
       1)Establishes the practice of pharmacy and provides for the licensing  
          and regulation of pharmacies and pharmacists by the Board of  
          Pharmacy (Board) within the Department of Consumer Affairs (DCA). 

        2) Defines "dangerous drug" or "dangerous device" as any drug or  
           device unsafe for self-use in humans or animals, and includes the  
           following:

           a)   Any drug that bears the legend: "Caution: federal law  
             prohibits dispensing without prescription," "Rx only," or words  
             of similar import.

           b)   Any device that bears the statement: "Caution: federal law  
             restricts this device to sale by or on the order of a ____," "Rx  
             only," or words of similar import, the blank to be filled in with  
             the designation of the practitioner licensed to use or order use  
             of the device.

           c)   Any other drug or device that by federal or state law can be  





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             lawfully dispensed only on prescription or furnished.  (Business  
             and Professions Code (BPC) � 4022)

        1) Defines "wholesaler" as a person who acts as a wholesale merchant,  
           broker, jobber, customs broker, reverse distributor, agent, or a  
           nonresident wholesaler, who sells for resale, or negotiates for  
           distribution, or takes possession of, any drug or device. Provides  
           that unless otherwise authorized by law, a wholesaler may not  
           store, warehouse, or authorize the storage or warehousing of drugs  
           with any person or at any location not licensed by the Board.  (BPC  
           � 4043)

       2)Specifies certain requirements regarding the dispensing and  
          furnishing of dangerous drugs and devices, and prohibits a person  
          from furnishing any dangerous drug or device except upon the  
          prescription of a physician, dentist, podiatrist, optometrist,  
          veterinarian or naturopathic doctor, as specified.  (BPC � 4059) 

        3) Provides that no person shall act as a wholesaler of any dangerous  
           drug or dangerous device unless he or she has obtained a license  
           from the Board.  Requires a separate license for each place of  
           business owned or operated by a wholesaler.  (BPC � 4160)

        4) Prohibits a person or entity from:  (BPC � 4169)

           a)   Purchasing, trading, selling or transferring dangerous drugs  
             or dangerous devices at wholesale with a person or entity that is  
             not licensed with the Board as a wholesaler or pharmacy.
             
           b)   Purchasing, trading, selling, or transfer dangerous drugs that  
             the person knew or reasonably should have known were adulterated.

           c)   Purchasing, trading, selling, or transfer dangerous drugs that  
             the person knew or reasonably should have known were misbranded.

           d)   Purchasing, trading, selling, or transfer dangerous drugs or  
             dangerous devices after the beyond use date on the label.  

        1) Requires records of the acquisition or disposition of dangerous  
           drugs or dangerous devices to be maintained for at least three  
           years.  (Id)

        2) Authorizes a primary care clinic to purchase drugs at wholesale for  
           the administration and dispensing under the direction of a  
           physician and surgeon to patients registered at the clinic. (BPC �  
           4180).





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        Existing law, the Health and Safety Code (HSC):

        1)Establishes a voluntary drug repository and distribution program  
          (Program) for the purpose of distributing surplus medications to  
          persons in need of financial assistance to ensure access to  
          necessary pharmaceutical therapies.  (Health and Safety Code (HSC) �  
          150200-150207)

        2)Makes the following definitions:

           a)   "Eligible entity" means a licensed pharmacy that is county  
             owned or that contracts with the county pursuant to this division  
             and is not on probation with the Board, a licensed pharmacy that  
             is owned and operated by a primary care clinic that is licensed  
             by the State Department of Public Health (DPH) and is not on  
             probation with the Board, a primary care clinic that is licensed  
             by DPH and licensed to administer and dispense drugs and is not  
             on probation with Board.

           b)   "Medication" or "medications" means a dangerous drug, as  
             defined in BPC � 4022 above.

           c)   "Participating entity" means an eligible entity that has  
             received written or electronic documentation from the county  
             health department and that operates a Program.  
           (HSC � 150202)


        1)Authorizes a county to establish a Program, by an action of the  
          county board of supervisors or by an action of the public health  
          officer of the county, as directed by the county board of  
          supervisors.  Requires the county to notify the Board within 30 days  
          from the date it establishes a Program.  (HSC � 150204)

        2)Provides that a participating entity shall disclose to the county  
          health department on a quarterly basis the name and location of the  
          source of all donated medication it receives.  Provides that a  
          participating primary care clinic shall disclose to the county  
          health department the name of the licensed physician who shall be  
          accountable to the Board for the clinic's Program operations.  (Id)

        3) Provides for the following related to medication donated to the  
          Program:  (Id)

           a)   The medication shall not be a controlled substance.





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           b)   The medication shall not have been adulterated, misbranded, or  
             stored under conditions contrary to standards set by the United  
             States Pharmacopoeia (USP) or the product manufacturer.

           c)   The medication shall not have been in the possession of a  
             patient or any individual member of the public, and in the case  
             of medications donated by a health or care facility, shall have  
             been under the control of a staff member of the health or care  
             facility who is licensed in California as a health care  
             professional or has completed, at a minimum, certain training  
             requirements.

           d)   Only medication that is donated in unopened, tamper-evident  
             packaging or modified unit dose containers that meet USP  
             standards is eligible for donation to the Program, provided lot  
             numbers and expiration dates are affixed. Medication donated in  
             opened containers shall not be dispensed by the Program and once  
             identified, shall be quarantined immediately and handled and  
             disposed of in accordance with the Medical Waste Management Act.

           e)   A pharmacist or physician at a participating entity shall use  
             his or her professional judgment in determining whether donated  
             medication meets certain standards before accepting or dispensing  
             any medication under the Program.

           f)   A pharmacist or physician shall adhere to standard pharmacy  
             practices, as required by state and federal law, when dispensing  
             all medications.

           g)   Medication that is donated to the Program shall either be  
             dispensed to an eligible patient, destroyed, returned to a  
             reverse distributor or licensed waste hauler or transferred to  
             another participating entity within the county to be dispensed to  
             eligible patients.  Medication that is donated shall not be  
             transferred by any participating entity more than once, and after  
             it has been transferred, shall be dispensed to an eligible  
             patient, destroyed, or returned to a reverse distributor or  
             licensed waste hauler.  Medication transferred pursuant to this  
             paragraph shall be transferred with documentation that identifies  
             the drug name, strength, and quantity of the medication, and the  
             donation facility from where the medication originated shall be  
             identified on medication packaging or in accompanying  
             documentation. 

           h)   Medication that is donated to the Program that does not meet  





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             the above requirements shall not be distributed or transferred  
             under this program and shall be either destroyed or returned to a  
             reverse distributor. 

           i)   Medication donated to the Program shall be maintained in the  
             donated packaging units until dispensed to an eligible patient  
             under this program, who presents a valid prescription. When  
             dispensed to an eligible patient under the Program, the  
             medication shall be in a new and properly labeled container,  
             specific to the eligible patient and ensuring the privacy of the  
             individuals for whom the medication was initially dispensed.  
             Expired medication shall not be dispensed.

           j)   Medication donated to the Program shall be segregated from the  
             participating entity's other drug stock by physical means, for  
             purposes including, but not limited to, inventory, accounting,  
             and inspection.

           aa)  A participating entity shall keep complete records of the  
             acquisition and disposition of medication donated to, and  
             transferred, dispensed, and destroyed under the Program. These  
             records shall be kept separate from the participating entity's  
             other acquisition and disposition records and be readily  
             retrievable.

           bb)  Local and county protocols established conform to the Pharmacy  
             Law regarding packaging, transporting, storing, and dispensing  
             all medications.

           cc)  County protocols established for packaging, transporting,  
             storing, and dispensing medications that require refrigeration,  
             including, but not limited to, any biological product as defined  
             in Section 351 of the Public Health Service Act (42 U.S.C. Sec.  
             262), an intravenously injected drug, or an infused drug, shall  
             include specific procedures to ensure that these medications are  
             packaged, transported, stored, and dispensed at appropriate  
             temperatures and in accordance with USP standards and the  
             Pharmacy Law.

           dd)  A participating entity shall follow the same procedural drug  
             pedigree requirements for donated drugs as it would follow for  
             drugs purchased from a wholesaler or directly from a drug  
             manufacturer. 

        1)Provides that a prescription drug manufacturer, wholesaler,  
          governmental entity, participating entity, pharmacist or physician  





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          who accepts or dispenses prescription drugs and a licensed health or  
          care facility or a pharmacy are not subject to criminal or civil  
          liability for injury caused when donating, accepting or dispensing  
          prescription drugs under a Program.  (HSC � 150205)
        
        This bill:

        1) Establishes a licensure category under the authority of the Board  
           for a "surplus medication collection and distribution intermediary"  
           (Intermediary) operating for the purpose of facilitating the  
           donation of medications to, or transfer of medications between,  
           participating entities under a county's unused medication  
           repository and distribution program (Program).   

        2) Requires an Intermediary to provide the Board information on a form  
           as part of its application for licensure, including the name,  
           address, usual occupation, and professional qualifications, if any,  
           of the applicant.  Provides that if the applicant is an entity  
           other than a natural person, the application shall state the  
           information as to each person beneficially interested in that  
           entity. Provides that the Intermediary license shall be renewed  
           annually.  

        3) Provides that in any case where the Intermediary licensure  
           applicant is a charitable organization described in Section 501 (c)  
           (3) of the Internal Revenue Code, the applicant shall furnish the  
           Board with the organization's Articles of Incorporation and the  
           names of the controlling members.

        4) Establishes an Intermediary licensure and renewal fee of $300.   
           Exempts an Intermediary that is government owned or nonprofit  
           organization from the fee requirement. 

        5) Exempts an Intermediary licensee from licensure as a wholesaler.

        6) Requires an Intermediary to keep and maintain for three years  
           complete records for which it facilitated the donation of  
           medications to, or transfer of medications between, participating  
           entities under the Program.   

        7) Defines "donor organization" as any of the following health and  
           care facilities that may donate centrally stored unused medications  
           under the Program:

           a)   A licensed general acute care hospital.






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           b)   A licensed acute psychiatric hospital.

           c)   A licensed skilled nursing facility, including a skilled  
             nursing facility designated as an institution for mental disease.

           d)   A licensed intermediate care facility.

           e)   A licensed intermediate care facility/developmentally  
             disabled-rehabilitative facility.

           f)   A licensed intermediate care facility/developmentally  
             disabled-nursing facility.

           g)   A licensed correctional treatment center.

           h)   A licensed psychiatric health facility.

           i)   A licensed chemical dependency recovery hospital.

           j)   A licensed residential care facility for the elderly with 16  
             or more residents.

           aa)  An approved mental health rehabilitation center.

        8)Adds an Intermediary to the list of existing persons and entities  
          persons which shall not be subject to criminal or civil liability  
          for injury caused when donating, accepting, or dispensing  
          prescription drugs in compliance with the Program.

        9)Prohibits an Intermediary from taking possession, custody, or  
          control of dangerous drugs and devices.

        10)Requires an Intermediary to ensure that notification is provided to  
          participating entities that a package has been shipped, when the  
          surplus medication collection and distribution intermediary has  
          knowledge of the shipment and provided logistical support to  
          facilitate a shipment directly from a donor organization.
             
        11)Prohibits an Intermediary from directing a donor organization to  
          select a specific participating entity to receive surplus  
          medications.

        12)Authorizes an Intermediary to charge membership, administrative, or  
          overhead fees sufficient to cover the reasonable costs of the  
          support and services provided in facilitating the donation of  
          medications to, or transfer of medications between, participating  





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          entities.

        13)Authorizes an Intermediary to contract directly with a county to  
          facilitate the donation of medications to, or transfer of  
          medications between, participating entities and provide general  
          support in the Program.

        FISCAL EFFECT:  Unknown.  This bill is keyed "fiscal" by Legislative  
        Counsel.

        COMMENTS:
        
        1. Purpose.  The  Author  is the Sponsor of this measure.  According to  
           the Author, current law accounts for wholesale activities and the  
           appropriate licensing for those activities, but does not account  
           for third party intermediaries.  Third party intermediaries provide  
           significantly different services than a wholesaler, and therefore  
           need licensing that reflects those services.  

        2. Background.  The issue of rising prescription drug costs, coupled  
           with concerns about methods for disposal of unused or expired  
           medication has led to efforts throughout the nation to reuse or  
           recycle medication from certain, controlled health care settings  
           and in turn make that medication available to indigent patients.  

           Estimates of American prescription drug spending have reached as  
           far as the hundreds of billions of dollars annually.  According to  
           the 2009 California Health Interview Survey conducted by the  
           University of California Los Angeles, 5.4 million Californians, or  
           14.5 percent of the state's population, were uninsured. Of the  
           insured in California, 7 percent or 2.2 million people did not have  
           coverage for prescription drugs.  
               
           For many years, a common practice at many health care facilities  
           has been to dispose of unused pharmaceuticals by flushing them down  
           the toilet or pouring them down the drain, which in turn impacts  
           water quality and water supply.  According to a report by the  
           Environmental Protection Agency (EPA), Unused Pharmaceuticals in  
           the Health Care Industry, this practice stems from certain  
           regulations governing acceptable methods for destroying unused  
           drugs, as well as factors like size, ease and access of disposal  
           and cost.  Certain federal regulations constrain how some  
           medications are destroyed or disposed, including the Controlled  
           Substances Act (which includes disposal down the drain as an  
           acceptable destruction option), Resource Conservation and Recovery  
           Act (which requires certain types of medication and other hazardous  





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           wastes to be transported in approved containers to permitted  
           hazardous waste disposal facilities by a hazardous waste  
           transporter, a costly effort for many health facilities) and the  
           Health Insurance Portability and Accountability Act (which requires  
           long-term care facilities to destroy all pharmaceutical labels that  
           contain personal information).  The report states that some  
           facilities are flushing to sewers as a primary means of disposal  
           because it is easy and accessible, and in the past, public health  
           agencies and health-related organizations advised the public to  
           destroy unused medications this way as well.           

        3. California's Efforts to Donate Unused Medication.   SB 798   
           (Simitian, Chapter 444, Statutes of 2005) took effect in 2006,  
           authorizing California counties to establish a "surplus  
           prescription drug collection and distribution program" (Program)  
           for the distribution of unused, unexpired medication to medically  
           indigent patients.  Under the Program, counties could adopt an  
           ordinance to establish such a Program, under which skilled nursing  
           facilities (SNFs), and SNFs that are institutions for mental  
           disease, drug wholesalers, and drug manufacturers could donate  
           unused medications to county-owned pharmacies, or pharmacies that  
           contract with the county for dispensing to medically indigent  
           patients free of charge.  Prior to the enactment of SB 798, SNFs  
           were required to either destroy the drugs in the presence of a  
           pharmacist or nurse, or return the drugs to the issuing pharmacy  
           (if unopened and in a sealed container) for disposition.  

            SB 1329  (Simitian, Chapter 709, Statutes of 2012) made a number of  
           changes to the way a Program could be authorized and the entities  
           eligible to donate medications under a Program.   The bill  
           authorized a county public health officer, as delegated by a county  
           board of supervisors, to implement a Program, in addition to  
           Program implementation via county ordinance as authorized in SB  
           798.  SB 1329 also added several categories of licensed health care  
           facilities that may donate medications.  The bill also allowed both  
           primary care clinic pharmacies and primary care clinics that have  
           Board licensees, to administer and dispense medication, provided  
           these Board licensees are in good standing with the Board.  SB 1329  
           established procedures relating to county and Board approval of  
           participating entities, as well as authority for a county and the  
           Board to prohibit a certain entity from participating in a Program.  
            

           To date, two counties in California (Santa Clara and San Mateo)  
           have established a Program through ordinance, although the Santa  
           Clara Program is the only current operational program.  As a result  





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           of changes in SB 1329, medication can be donated from a number of  
           organizations, facilities and entities throughout the state, but  
           the only recipients of donated medications must be located within  
           Santa Clara County:

           Program efforts in Santa Clara County are coordinated by Supporting  
           Initiatives to Redistribute Unused Medication (SIRUM) and are  
           estimated to have resulted in significant impact and savings since  
           2009:

                "            772,000 units of medicine have been  
                     redistributed;
                "            $2 million of medicine have been donated;
                "            Thousands of estimated uninsured patients have  
                     been assisted;
                "            150 medicine donors are participating.

        1. Similar Programs in Other States.  According to the National  
           Conference of State Legislatures (NCSL), as of September 2012, at  
           least 38 states and Guam have enacted similar laws and programs  
           which are similar to the Program a county may establish under  
           current California law. While not all authorized programs are  
           operational, California is unique in that a Program is established  
           at the county level, while many other state programs exist at the  
           state level or as part of a statewide effort. 

           The majority of laws throughout the nation authorizing the creation  
           of a Program have the following characteristics: 

                     Authorize the return of prescription drugs in single use  
                or sealed packaging from state programs, nursing homes and  
                other medical facilities.

                     Provisions in place for the financial terms of the  
                                                           donations or regulating sales.

                     Restrictions are in place aimed at assuring purity,  
                safety and freshness of the products.

           According to NCSL,  all  Programs provide that: 

                     Donated drugs must not be expired and must have a  
                verified future expiration date.

                     Controlled substances defined by the DEA must be  
                excluded.





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                     A state-licensed pharmacist or pharmacy must be part of  
                the verification and distribution process.

                     Each patient receiving a drug must have a valid  
                prescription form. 

           Examples of similar programs to California's:

                      Connecticut  (HB 6002, 2000) allows long-term care  
                facilities to donate prescription drug products to vendor  
                pharmacies or the state Department of Social Services for drug  
                repackaging and reimbursement. The drugs are then donated to  
                eligible patients. The drugs must be sealed in individually  
                packaged units, returned to the vendor pharmacy within the  
                recommended shelf, inspected by a licensed pharmacist, and  
                cannot be a controlled substance. 

                      Ohio  (HB 221, 2003) allows any person, drug  
                manufacturer, or healthcare facility to donate prescription  
                drugs to any pharmacy, hospital, or nonprofit clinic that has  
                elected to participate in the program and meets certain  
                eligibility requirements established in rules adopted by their  
                Pharmacy Board. The drugs can then be donated to individuals  
                with a prescription. The drugs must be in their original  
                sealed tamper-evident unit dose packaging. 

                      Arkansas  (HB 1031, 2005) allows a nearby nursing  
                facility to donate drugs to charitable clinic pharmacies. The  
                drugs are then donated to qualified indigent patients who are  
                not eligible for Medicaid and cannot afford private health  
                insurance. The charitable pharmacy can only accept drugs in  
                their original sealed and tamper-evidence packaging, and it  
                cannot accept controlled substances. 

                      Iowa  (HF 724, 2005) allows any person to donate  
                prescription drugs and supplies to participating medical  
                facilities or pharmacies. The drugs are donated to individuals  
                or other eligible facilities or pharmacies for use. The drugs  
                must be inspected and in their original sealed and tamper  
                evidence packaging. The program is operated by the Iowa  
                Prescription Drug Corporation, a non-profit organization that  
                contracts with the State Department of Public Health. 

                      Oklahoma  (SB 1640, 2006) which inspired SB 798, allows  
                pharmaceutical manufacturers and certain medical and skilled  





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                care facilities to donate unused prescription drugs to state,  
                county, and city pharmacies and charitable clinics for the  
                purpose of distributing the medications. The drugs are then  
                donated to Oklahoma residents who are medically indigent.  
                Controlled substances are not accepted. 

                      Guam  established medicine banks in 2004 which distribute  
                donated drugs to indigent individuals. 

            Colorado  ,  Florida  ,  Kentucky  ,  Minnesota  , and  Nebraska  have also  
           enacted programs but only for cancer drugs.

            Michigan  ,  New Mexico  ,  Alabama  and I  ndiana  programs allow donations  
           between correctional facilities. 

            New Hampshire  only allows manufacturer's samples to be donated.

            New York  allows donations back to the specific pharmacy that  
           initially distributed it.

            North Carolina  ,  Oregon  ,  South Carolina  , and  West Virginia  have  
           state medication repurposing policies but do not allow  
           repositories. 

        1. Prior Legislation.   SB 1329  (Simitian, Chapter 709, Statutes of  
           2012) revised and recasted provisions authorizing a county to  
           establish a drug repository and distribution program, to authorize  
           a program to be established by an action of the county board of  
           supervisors, or by the county public health officer, as specified  
           and expanded the types of entities that are eligible to participate  
           in a program.  

            SB 798  (Simitian, Chapter 444, Statutes of 2005) authorized the  
           establishment of a voluntary prescription drug collection and  
           distribution program for the purpose of distributing surplus  
           prescription drugs to medically indigent patients free of charge.
         
         6.Board of Pharmacy Position.  At its October meeting, the Board of  
          Pharmacy adopted a "Support If Amended" position on this bill. The  
          Board's position reflects a prior version of the measure which did  
          not specify the term and renewal requirements of the new  
          Intermediary license.  The January 7 version of the bill authorizes  
          the Board to issue an annual Intermediary license which shall be  
          renewed annually.  







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        SUPPORT AND OPPOSITION:
        
         Support:  

        Bethesda Home
        California Association of Health Facilities
        Californians Against Waste
        Lincoln Glen Manor and Nursing Facility
        Santa Clara County Board of Supervisors
        Supporting Initiatives to Redistribute Unused Medication (SIRUM)
         
        Support if Amended:
         
        Board of Pharmacy
         
        Opposition:  

        None received as of January 8, 2014



        Consultant:Sarah Mason and Vincent Chee