BILL ANALYSIS                                                                                                                                                                                                    �



                                                                  SB 204
                                                                  Page  1

          Date of Hearing:  June 17, 2014

                            ASSEMBLY COMMITTEE ON HEALTH
                                 Richard Pan, Chair
                    SB 204 (Corbett) - As Amended:  June 10, 2014

           SENATE VOTE  :  Not relevant. 
           
          SUBJECT  :  Prescription drugs: labeling.

           SUMMARY  :  Requires Board of Pharmacy (BOP) to survey pharmacists  
          and electronic health record (EHR) vendors to determine  
          utilization of standardized prescription directions for use  
          adopted pursuant to Board regulations.  Specifically,  this bill  :  
           

          1)Requires the BOP survey pharmacists to collect data on whether  
            and how often pharmacists utilize standardized directions for  
            use, challenges or barriers for use, and other directions used  
            by pharmacists. 

          2)Requires the BOP to conduct a survey of vendors that provide  
            EHRs to pharmacies and prescribers to determine the type of  
            directions for use included in the software.  Requires the  
            survey to include, but not be limited to, whether standardized  
            directions for use are used in the software, challenges or  
            barriers for use, and other directions used by the vendor. 

          3)Specifies the surveys to be conducted with other surveys  
            performed during routine course of business. 

          4)Requires the BOP to report the finding of the surveys at the  
            July 2016 BOP meeting, and publish the findings on its  
            Internet Website. 

          5)Sunsets the provisions of this bill on January 1, 2020. 

           EXISTING LAW  :  

          1)Provides for the practice of pharmacy and the licensing and  
            regulation of pharmacies and pharmacists by the BOP within the  
            Department of Consumer Affairs.

          2)Specifies certain requirements regarding the dispensing and  
            furnishing of dangerous drugs and devices and prohibits a  








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            person from furnishing any dangerous drug or device except as  
            prescribed by a physician, dentist, podiatrist, optometrist,  
            or veterinarian.

          3)Requires that each prescription dispensed by a pharmacist to  
            be in a container meeting state and federal specification, and  
            requires the label to include certain information, including:

             a)   Unless otherwise ordered by the prescriber, the  
               manufacturer's trade name of the drug or the generic name  
               and the name of the manufacturer, as specified;

             b)   The directions for the use of the drug;

             c)   The name of the patient or patients;

             d)   The name of the prescriber, as specified;

             e)   The date of issue;

             f)   The name and address of the pharmacy and prescription  
               number or other means of identifying the prescription;

             g)   The strength of the drug or drugs dispensed;

             h)   The quantity of the drug or drugs dispensed;

             i)   The expiration date of the effectiveness of the drug  
               dispensed;

             j)   The condition or purpose for which the drug was  
               prescribed if the condition or purpose is indicated on the  
               prescription; and,

             aa)  The physical description of the dispensed medication,  
               including its color, shape, and any identification code  
               that appears on the tablets or capsules.

           EXISTING REGULATIONS  :

          1)Requires labels on drug containers dispensed to patients in  
            California to conform to the following format:

             a)   Each of the following must be clustered into one area of  
               the label that comprises at least 50% of the label and be  








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               printed in at least 10-point sans serif typeface, or, if  
               requested by the consumer, at least a 12-point typeface,  
               and listed in the following order:

               i)     Name of the patient;
               ii)    Name of the drug and strength of the drug;
               iii)   Directions for the use of the drug; and, 
               iv)    The condition or purpose for which the drug was  
                 prescribed if the condition or purpose is indicated on  
                 the prescription.

             b)   Requires for added emphasis, the label to highlight in  
               bold typeface or color, or use blank space to set off the  
               items listed in 1) a) above; and,

             c)   Requires the remaining elements that are required to be  
               printed on a label, as well as any other items of  
               information appearing on the label or the container, to be  
               printed so as not to interfere with the legibility or  
               emphasis of the primary elements specified in 1) a) above.   


          2)Requires the BOP, by October 1, 2011, and updated as  
            necessary, to publish on its Website translation of specified  
            directions for use into at least five languages other than  
            English, to facilitate their use by California pharmacies.   
            Specifies phrases that are required to be used for  directions  
            for use  , including:

             a)   Take 1 [insert appropriate dosage form] at bedtime;
             b)   Take 1 [insert appropriate dosage form] in the morning;
             c)   Take 1 [insert appropriate dosage form] in the morning,  
               and Take 1 [insert appropriate dosage form] at bedtime;
             d)   Take 1 [insert appropriate dosage form] in the morning,  
               1 [insert appropriate dosage form] at noon, and l [insert  
               appropriate dosage form] in the evening; or,
             e)   If you have pain, take [insert appropriate dosage form]  
               at a time. Wait at least __ hours before taking again. Do  
               not take more than [appropriate dosage form] in one day.

          3)Requires the BOP to collect and publish on its Website  
            examples of labels conforming to these requirements, to aid  
            pharmacies in label design and compliance.

          4)Requires a pharmacy to have policies and procedures in place  








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            to help patients with limited or no English proficiency  
            understand the information on the label as specified in 1) a)  
            above in the patient's language.  Requires the pharmacy's  
            policies and procedures to be specified in writing and to  
            include, at a minimum, the selected means to identify the  
            patient's language and to provide interpretive services in the  
            patient's language.  Requires the pharmacy, at a minimum, to  
            provide interpretive services in the patient's language, if  
            interpretive services in such language are available, during  
            all hours that the pharmacy is open, either in person by  
            pharmacy staff or by use of a third-party interpretive service  
            available by telephone at or adjacent to the pharmacy counter.
           
          FISCAL EFFECT  :  This bill, as amended, has not yet been analyzed  
          by a fiscal committee.  
           
           COMMENTS  :

           1)PURPOSE OF THIS BILL  .  According to the author, although the  
            BOP adopted regulations to develop a patient-centered  
            prescription label and standardized directions for use in  
            2010, the BOP does not know how many doctors are using these  
            standardized directions, nor do they have any method for  
            determining whether or not pharmacies are utilizing them.  The  
            BOP also does not know and has no method for determining if  
            the vendors of EHRs are using the standardized directions for  
            use in the products that they market to prescribers and  
            pharmacies.  The author further states that the BOP should  
            determine if the standardized directions for use are being  
            utilized and what the barriers are to using the standardized  
            directions in prescriptions and EHRs for prescribers and  
            pharmacists.  These surveys will provide the BOP with the  
            necessary data to determine how to better ensure the use of  
            this important aspect of the patient-centered regulations.

           2)BACKGROUND  .  

             a)   Medication Errors.  SCR 49 (Speier), Resolution Chapter  
               123, Statutes of 2005, establishes the Medication Errors  
               Panel (Panel) which published a report in March 2007  
               entitled, "Prescription for Improving Patient Safety:  
               Addressing Medication Errors."  The report listed six  
               general goals to reduce medication errors.  Under each goal  
               were recommendations (12 in all) and methods to accomplish  
               each recommendation.  The Panel report states that "the  








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               information that consumers need to know about their  
               medication is often complex and may include unfamiliar  
               language or concepts.  Expecting a consumer to retain all  
               the pertinent knowledge from a brief verbal encounter may  
               not be reasonable in many instances."  Although the Panel  
               did not come to consensus on the most important subset of  
               consumers that are at "high risk" for medication errors, it  
               did acknowledge that there are a variety of factors which  
               may increase an individual's risk for experiencing a  
               medication error.  These include:  i) low health literacy;  
               ii) limited English proficiency; iii) cultural incongruence  
               with healthcare providers; iv) physical, cognitive, and/or  
               other impairments that make understanding and/or complying  
               with medication instructions difficult; v) age at either  
               end of the age spectrum (the variability of a medication's  
               response, metabolism, and dose increases in children and  
               seniors); vi) multiple medications; vii) multiple  
               prescribers; viii) non-prescription medication use  
               (including herbals, dietary supplements, alcohol, and  
               tobacco); and, ix) medication procurement from more than  
               one pharmacy including mail-order. The Panel did state that  
               these factors must be taken into consideration in the  
               development of any consumer education efforts.  

             One bill that was pursued in response to the Panel report was  
               SB 472 (Corbett), Chapter 470, Statutes of 2007.  SB 472  
               establishes the California Patient Medication Safety Act,  
               which requires the BOP to promulgate regulations on or  
               before January 1, 2011, that require a standardized,  
               patient-centered prescription drug label on all  
               prescription medicine dispensed to patients.  Additionally,  
               the BOP was required to report to the Legislature by  
               January 1, 2010, on its progress in implementing these  
               regulations.  

             b)   Report to the Legislature on the Implementation of SB  
               472.  Pursuant to SB 472, the BOP submitted its report  
               entitled, "Prescription Drugs: Labeling Requirements" to  
               the Legislature in January 2010.  The report indicated the  
               steps the BOP took prior to adopting the final regulations  
               to implement SB 472.  Specifically, the BOP established a  
               "SB 472 Medication Label Subcommittee" in January 2008 to  
               conduct public forums and to work with organizations and  
               individuals to develop recommendations to implement the  
               provisions of the law to establish a patient-centered  








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               prescription drug label.  In May 2008, the BOP developed an  
               open-ended prescription label survey for distribution at  
               public outreach events.  A total of 606 consumers completed  
               the surveys.  Specifically, when asked what to change on  
               the prescription label, 30.1% responded that print should  
               be larger or darker; 24.5% indicated nothing needs to be  
               changed on the label; and, 12% responded that the purpose  
               of the drug must be included.  The BOP considered testimony  
               and information provided from the public, the  
               pharmaceutical industry, pharmacy professionals, and  
               literacy subject matter experts on medical literacy  
               research, improved directions for use, improved font types  
               and sizes, the placement of information that is  
               patient-centered, the needs of patients with limited  
               English proficiency, the needs of senior citizens, and  
               technology requirements necessary to implement the  
               standards developed.  BOP members were also provided with  
               research articles on designing patient-centered labels.  In  
               2009, the BOP discussed the requirements of the regulation  
               at regularly scheduled meetings and the final regulations  
               were adopted in 2010.   
              
             c)   BOP Regulations on Translations and Interpretive  
               Services.  Regulations adopted by the BOP in 2010 entitled  
               "Patient-Centered Labels for Prescription Drug Containers"  
               require a standardized, patient-centered prescription drug  
               label on all prescriptions dispensed to patients.  Among  
               other requirements, the regulations require pharmacies to  
               have policies and procedures in place to help patients with  
               limited or no English proficiency to understand specified  
               information on the label in the patient's language.  The  
               pharmacy's policies and procedures must be specified in  
               writing and are required to include at minimum, the  
               selected means to identify the patient's language and to  
               provide interpretive services in the patient's language.   
               The pharmacy must provide interpretive services in the  
               patient's language, if interpretive services in such  
               language are available, during all hours that the pharmacy  
               is open, either in person by pharmacy staff or by use of  
               third-party interpretive service available by telephone at  
               or adjacent to the pharmacy counter.  

           3)SUPPORT  .  The California Pan Ethnic Health Network, sponsor of  
            this bill, states that a large percentage of patients  
            misunderstand dosage instructions on their labels.  Simple,  








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            explicit, and specific instructions can help alleviate  
            patients' misunderstanding.  Pursuant to previous legislation,  
            the BOP Pharmacy adopted standardized instruction, but there  
            is no data about whether pharmacies are actually using the  
            instructions. 

           4)DOUBLE REFERRAL  .  This bill is double referred, upon passage  
            of this Committee, it will be referred to the Assembly  
            Business, Professions & Consumer Protection Committee.

           5)PREVIOUS LEGISLATION  .  

             a)   SB 205 (Corbett) of 2013 would have required the  
               information on the prescription label to be printed in at  
               least a 12-point sans serif typeface.  SB 205 was vetoed by  
               the Governor, stating:

                 "The BOP of Pharmacy is required to provide an  
                 update of its 2010 labeling guidelines to the  
                 Legislature next month. I prefer to wait for their  
                 findings before mandating such a change."

             b)   AB 1136 (Levine), Chapter 304, Statutes of 2013,  
               requires a pharmacist to include a written label on the  
               drug container indicating that the drug may impair a  
               person's ability to operate a vehicle or vessel.  

             c)   SB 472 requires the BOP to promulgate regulations that  
               require, on or before January 1, 2011, a standardized,  
               patient-centered prescription drug label on all  
               prescription medication dispensed to patients in  
               California. 

             d)   SCR 49 establishes a panel to study the causes of  
               medication errors and recommend changes in the health care  
               system that would reduce errors associated with the  
               delivery of prescription and over-the-counter medication to  
               consumers.

             e)   SB 292 (Speier), Chapter 544, Statutes of 2003, requires  
               prescription labels to include a physical description of  
               the drug, including the color, shape, and any  
               identification code that appears on the tablet or capsule.

             f)   AB 2099 (Epple), Chapter 397, Statutes of 1993, requires  








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               that the condition for which the drug is being prescribed  
               must be included on the label if the patient requests that  
               information on the label.

           



          REGISTERED SUPPORT / OPPOSITION  :

           Support 
           
          California Pan Ethnic Health Network (sponsor)
          California Alliance for Retired Americans
          Latino Coalition for a Healthy California 
          Western Center on Law and Poverty
           
            Opposition  

          None on file for this version of the bill. 

           Analysis Prepared by  :    Dharia McGrew / HEALTH / (916) 319-2097