BILL ANALYSIS                                                                                                                                                                                                    �






                             SENATE COMMITTEE ON HEALTH
                          Senator Ed Hernandez, O.D., Chair

          BILL NO:       SB 1438
          AUTHOR:        Pavley
          AMENDED:       April 10, 2014
          HEARING DATE:  April 24, 2014
          CONSULTANT:    Diaz

           SUBJECT  :  Controlled substance: opioid antagonists.
           
          SUMMARY :  Adds peace officers to existing law regarding the use  
          and administration of an opioid antagonist. Requires the  
          Emergency Medical Services Authority to develop training and  
          standards and to promulgate regulations for the use and  
          administration of naloxone hydrochloride by all prehospital  
          emergency care personnel. Allows local emergency medical  
          services agencies to develop training and standards and to  
          promulgate regulations for the use and administration of  
          naloxone hydrochloride by prehospital emergency care personnel  
          under their jurisdiction in lieu of those developed by the  
          Emergency Medical Services Authority. Authorizes hospitals and  
          trauma centers to share information, as specified, regarding  
          controlled substances overdose trends.

          Existing law:
           Civil Code
           1.Defines "opioid antagonist" as naloxone hydrochloride  
            (naloxone) that is approved by the federal Food and Drug  
            Administration (FDA) for the treatment of an opioid overdose.

          2.Allows a licensed health care provider who is authorized to  
            prescribe naloxone to prescribe and dispense or distribute the  
            medication to a person at risk of an overdose or to a family  
            member, friend, or other person in a position to assist the  
            person at risk of overdose. Allows a licensed health care  
            provider to issue standing orders for these purposes.

          3.Requires a person who is prescribed or possesses naloxone  
            pursuant to a standing order to receive training by an  
            overdose prevention and treatment training program, as  
            specified. Specifies that a person who is prescribed naloxone  
            directly from a licensed prescriber, and not through a  
            standing order, is not subject to the training requirement.

          4.Exempts a health care provider who acts with reasonable care  
                                                         Continued---



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            in issuing a prescription for naloxone and any person who  
            possesses, distributed, or administers naloxone, with  
            reasonable care, from professional review, civil action, or  
            criminal prosecution.
           
          Health and Safety Code
           5.Requires the Emergency Medical Services Authority (EMSA) to  
            establish training and standards for all prehospital emergency  
            care personnel, as defined, regarding the characteristics and  
            method of assessment and treatment of anaphylactic reactions  
            and the use of epinephrine. Requires EMSA to promulgate  
            regulations for use by all prehospital emergency care  
            personnel.

          6.Requires the Attorney General to encourage research on the  
            misuse and abuse of controlled substances. Allows the Attorney  
            General to develop new and improved approaches, techniques,  
            systems, equipment, and devices to strengthen enforcement of  
            the Controlled Substances Act, and to enter into contracts  
            entities, as specified, to conduct demonstrations or special  
            projects that bear directly on the misuse and abuse of  
            controlled substances.
          
          This bill:
          1.Adds peace officers to the list of people who can receive a  
            prescription for an opioid antagonist for the purpose of  
            assisting a person at risk of an opioid-related overdose. Adds  
            peace officers to the list of people who can receive standing  
            orders for the distribution of an opioid antagonist for this  
            purpose.

          2.Requires EMSA to establish training and standards for all  
            prehospital emergency care personnel on the use and  
            administration of naloxone and other opioid antagonists and to  
            promulgate regulations for this purpose. Allows EMSA to  
            designate existing training and standards for this purpose.

          3.Allows a local emergency medical services agency to develop  
            training and standards and to promulgate regulations for  
            prehospital emergency medical care personnel under its  
            jurisdiction who use and administer naloxone in lieu of those  
            developed by EMSA.

          4.Authorizes hospitals and trauma centers to share information  
            with local law enforcement and local emergency medical  
            services agencies about controlled substance overdose trends.  




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            Specifies that this information shall only include the number  
            of overdoses and the substances suspected as the primary cause  
            of the overdoses and shall ensure patient confidentiality.

           FISCAL EFFECT  :  This bill has not been analyzed by a fiscal  
          committee.

           COMMENTS  :  
           1.Author's statement.  According to the author, California and  
            the nation are in the midst of a drug abuse crisis.  
            Prescription opioid and heroin abuse have precipitated a  
            public health epidemic marked by a spike in fatal overdoses.  
            While naloxone, an opiate antidote that reverses opiate  
            overdoses, has been used by paramedics and emergency medical  
            technicians (EMTs) in the state (now known as "Advanced EMTs")  
            to save lives for the last few decades, current law is unclear  
            about the ability of other first emergency responders, such as  
            law enforcement, to use this medication.   

            Recently, California has taken several steps to prevent  
            overdose fatalities. Legislation enacted last year expanded  
            the use of naloxone for health care providers, family,  
            friends, and other persons who may assist overdose victims,  
            but the law has been interpreted to lack specific clarity  
            about law enforcement's ability to carry and administer the  
            drug. 

            While paramedics and emergency medical technicians are often  
            the first to respond to a medical emergency, some localities  
            report that peace officers are increasingly the first to  
            encounter an overdose victim. A recent internal survey within  
            the San Diego Sheriff's Department found that sheriff's  
            deputies responded to over 200 overdose-related emergency  
            calls in the first nine months of 2013. In over 50 percent of  
            those cases, the sheriff's deputy was the first emergency  
            responder on the scene. Last month, in recognition of the  
            nationwide surge in opiate overdoses, U.S. Attorney General  
            Eric Holder echoed the plea made by the director of the White  
            House Office of National Drug Control Policy to train and  
            equip law enforcement officers with naloxone.  
            
          2.Deaths related to opioid overdose.  According to the Centers  
            for Disease Control and Prevention (CDC), there were nearly  
            37,000 drug overdose deaths in the United States in 2008 and  
            approximately 4,300 drug poisoning deaths in California.  




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            Counties experiencing the highest numbers of overdose deaths  
            were Alameda, Fresno, Kern, Los Angeles, Orange, Riverside,  
            Sacramento, San Bernardino, San Diego, San Francisco, and  
            Santa Clara. In 2009, 28,754 (91 percent) of all unintentional  
            poisoning deaths were caused most commonly by prescription  
            opioids, which include such drugs as methadone, hydrocodone  
            (Vicodin), and oxycodone (Oxycontin), followed by cocaine and  
            heroin. 

          3.Naloxone. According to the FDA, naloxone, which is not a  
            controlled substance, rapidly reverses the effects of opioid  
            overdose and is the standard treatment for overdose, which is  
            characterized by decreased breathing or heart rate or loss of  
            consciousness. The National Institute on Drug Abuse's Web site  
            states that, as of March 2014, 17 states have passed laws that  
            allow for wider prescribing of naloxone to those who can help  
            prevent overdoses, such as family and friends of drug addicts  
            and a wide array of emergency personnel, like police and  
            firefighters. Some overdose prevention programs use syringes  
            fitted with atomizers to enable to medication to be sprayed  
            into the nose. 

            In April 2014, the FDA announced the approval of a new  
            hand-held auto-injector to reverse opioid overdose. The  
            medication is injected into the muscle or under the skin. The  
            new device provides verbal instruction, similar to an  
            automated defibrillator. The FDA granted a fast-track  
            designation, which is designed to facilitate development and  
            to expedite the review of drugs to treat serious conditions  
            and fill unmet medical need, according to the FDA's Web site. 

          4.Results of naloxone distribution and administration. A 2012  
            CDC report on programs known to distribute naloxone documented  
            the reversal of more than 10,000 heroin overdoses. The  
            programs provided opioid overdose education and naloxone to  
            drug users and to those who might be present during a drug  
            overdose in order to help reduce overdose deaths. However, of  
            the 48 programs that responded, nearly half reported problems  
            in obtaining naloxone related to cost and a shortage of  
            supply.

            According to the Drug Policy Alliance's (DPA) Web site,  
            naloxone has been safely and effectively used for more than 40  
            years in ambulances and emergency rooms across the country.  
            Naloxone has no potential for abuse and side effects are rare.  
            DPA also cites ongoing research showing that expanding access  




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            to naloxone does not promote increased drug use or risk-taking  
            behavior that results in unintended overdoses.

          5.Double referral. This bill has been double referred. Should it  
            pass out of this committee, it will be referred to Senate  
            Public Safety Committee. 

          6.Related legislation. AB 1535 (Bloom) would authorize a  
            pharmacist to furnish naloxone if the pharmacist provides a  
            consultation to ensure the education of the person to whom the  
            drug is furnished and notification to the patient's primary  
            care provider of drugs or devices furnished to the patient.  
            Prohibits a pharmacist from permitting a person to waive the  
            consultation. Requires a pharmacist to complete a training  
            program on the use of opioid antagonists prior to furnishing  
            naloxone. This bill is currently in the Assembly  
            Appropriations Committee.

          7.Prior legislation. AB 635 (Ammiano), Chapter 707, Statutes of  
            2013, expanded the program in AB 2145 (Ammiano) Chapter 545,  
            Statues of 2010. statewide; deleted the sunset date and the  
            reporting requirements; and, modified the limited liability  
            provisions for both licensed health care professionals who  
            prescribe, dispense, or distribute naloxone and unlicensed  
            persons who act with reasonable care to administer naloxone to  
            a person who is experiencing or is suspected to be  
            experiencing an overdose.  
            
            AB 2145 (Ammiano) extended the sunset date of the seven-county  
            pilot program established under SB 767 (Ridley-Thomas),  
            Chapter 477, Statutes of 2007,  to January 1, 2016; extended  
            to January 1, 2015, the deadline for the requirement of local  
            health jurisdictions operating an overdose prevention program  
            to report, as specified, to the Senate and Assembly Committees  
            on Judiciary; and, added immunity for unlicensed trained  
            people who administer an opioid antidote in emergency  
            situations during which they believe that a person is  
            experiencing a drug overdose.  

            SB 767 (Ridley-Thomas) established a seven-county pilot  
            program until January 1, 2010, in which licensed health care  
            providers were given immunity from civil liability or criminal  
            prosecution when they prescribed naloxone to a person in  
            connection with an opioid overdose prevention and training  
            program on how to recognize and respond to an opiate overdose.  




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            Required local health jurisdictions operating an overdose  
            prevention program to report, as specified, to the Senate and  
            Assembly Committees on Judiciary by January 1, 2010.

            SB 1695 (Escutia), Chapter 678, Statutes of 2002,  authorized  
            counties to establish training and certification programs to  
            permit an EMT-I to administer naloxone by means other than  
            intravenous injection if he or she has completed training and  
            passed a test. Required EMSA to develop guidelines relating to  
            the county certification programs.

            SB 1134 (Escutia) of 2001 contained, among other things, the  
            provisions in SB 1695 above. SB 1134 was vetoed by Governor  
            Davis who cited cost reasons related to provisions in the bill  
            that required grants for drug overdose prevention programs.

            SB 851 (Oller) of 2001 required the EMSA to develop and  
            implement procedures and protocols to permit EMT-I's in Sierra  
            County to obtain training and certification to safely  
            administer emergency medical procedures, including naloxone,  
            that are outside of their scope of practice. This bill was  
            never heard in the Senate Health and Human Services Committee.

             8.   Support. DPA writes in support that SB 1438 is an  
               urgently needed measure to allow first responders to  
               administer opiate overdose reversal medication, naloxone,  
               to a person at risk of a fatal overdose. Naloxone has been  
               extensively researched and widely used by a number of  
               health care entities for decades and several states have  
               already expanded usage to peace officers with no reports of  
               negative outcomes for patient safety. DPA believes this  
               bill is part of a comprehensive strategy to combat the  
               epidemic of opiate overdoses in California. 



             9.   Policy Comment.
               a.     Local EMS agencies. This bill allows a local EMS  
                 agency to develop training, standards, and regulations  
                 for prehospital emergency medical care personnel for the  
                 use and administration of naloxone, in lieu of those  
                 developed by the EMSA. To help prevent a conflict,  
                 Committee staff suggests the following amendment to  
                 ensure that both local EMS agency and EMSA training,  
                 standards, and regulations are in line with best  
                 practices in the Substance Abuse and Mental Health  




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                 Administration's Opioid Overdose Prevention Toolkit.
                 
                 Section 1797.197 of the Health and Safety Code:

                 (a) The authority shall establish training and standards  
                 for all prehospital emergency care personnel, as defined  
                 pursuant to in paragraph (2) of subdivision (a) of  
                 Section 1797.189, regarding the characteristics and  
                 method of assessment and treatment of anaphylactic  
                 reactions and the use of epinephrine. The authority shall  
                 promulgate regulations regarding these matters for use by  
                 all prehospital emergency care personnel.
                 (b) (1) The authority shall establish training and  
                 standards for all prehospital emergency care personnel,  
                 as defined in paragraph (2) of subdivision (a) of Section  
                 1797.189, regarding the use and administration of  
                 naloxone hydrochloride and other opioid antagonists. The  
                 authority shall promulgate regulations regarding these  
                 matters for use by all prehospital emergency care  
                 personnel. The authority may designate existing training  
                 and standards for the use and administration of naloxone  
                 hydrochloride or another opioid antagonist to satisfy the  
                 requirements of this section.
                 (2) A local EMS agency may develop its own training and  
                 standards, and may promulgate regulations, in lieu of the  
                 training and standards and regulations developed by the  
                 authority pursuant to paragraph (1),  for the purpose of  
                 considering local need,  regarding the use and  
                 administration of naloxone hydrochloride and other opioid  
                 antagonists by prehospital emergency care personnel under  
                 the jurisdiction of that local EMS agency.
                  (3) The training, standards, and regulations in  
                 paragraphs (1) and (2) of subdivision (b) shall be in  
                 line with best practices in the Substance Abuse and  
                 Mental Health Services Administration's Opioid Overdose  
                 Prevention Toolkit.
                  (   3  4  ) The training described in paragraphs (1) and (2)  
                 shall satisfy the requirements of paragraph (1) of  
                 subdivision (d) of Section 1714.22 of the Civil Code.

                 
           SUPPORT AND OPPOSITION  :
          Support:  California State Sheriffs' Association
                    Drug Policy Alliance
                    California Chapter of the American College of  




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                    Emergency Physicians (prior version)
                    
          Oppose:   None received



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